B.R. Hartley, P. Tsokas, C. Hsieh, A.A. Fenton,
S. Marquez and T.C. Sacktor. SUNY Downstate Med. Ctr. and
NYU.
A351
534.7
Mapping the anatomical connectivity in the
language-specific cerebrocerebellar network.
I. George, S.
Christ and K. Aldridge. Univ. of Missouri-Columbia.
A352
534.8
The involvement of programmed cell death
(PDCD5) in the regulation of apoptosis in cerebral ischemia/
reperfusion injury.
C. Zhou, C. Chen, Z. Jiang, J. Yan and
Y. Chen. Peking Univ. Hlth. Sci. Ctr. and Ctr. for Human Dis.
Genomics.
535. NEUROBIOLOGY: NEURAL CELL BIOLOGY
Poster
s
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. 7:30
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A353
535.1
Molecular organization of the endocannabinoid
signaling system in the superficial spinal dorsal horn of rodents.
M. Antal. Univ. of Debrecen, Hungary.
A354
535.2
Myenteric Dogiel II neurons express nerve
growth factor.
M.D. Kawaja and C.N. Petrie. Queen’s Univ.,
Canada.
A355
535.3
Nuclear factor one controls a voltage-sensitive
developmental switch required for late neuronal maturation.
B.
Ding, W. Wang and D.L. Kilpatrick. Univ. of Massachusetts
Med. Sch.
A356
535.4
Expression of mineralocorticoid and
glucocorticoid receptors in pre-autonomic neurons of the rat
paraventricular nucleus.
J. Chen, C.E. Gomez-Sanchez, P.J.
May and E.P. Gomez-Sanchez. Univ. of Mississippi Med. Ctr.,
Univ. of Mississippi Med. Ctr. and G.V. (Sonny) Montgomery VA
Med. Ctr.
A357
535.5
Dysregulation of brain divalent metals ions
as a possible cause for lead-induced deficits in learning
and memory.
K.M. Khan, A. Rahman, S.M. Attur and T.S.
Srikumar. Kuwait Univ.
A358
535.6
Neurotensinergic periaqueductal gray-rostral
ventromedial medulla-spinal dorsal horn pathway.
Y. Li. Fourth
Military Med. Univ., China.
536. NEUROBIOLOGY: NEURONAL AND SPINAL
CORD DEGENERATION, REPAIR AND
REGENERATION
Poster
s
un
. 7:30
am
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Presentation time: 12:30
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-2:00
pm
A359
536.1
Levels of nitric oxide synthase and
cholecystokinin mRNA in the upper gastrointestinal tract of rats
following experimental spinal cord injury.
E. Swartz and G.M.
Holmes. Penn State Col. of Med.
A360
536.2
The effect of electrical stimulation and
testosterone on the expression of regeneration-associated
genes.
R.M. Meadows, K.P. McMillan, R.J. Batka, T.J. Brown
and K.J. Jones. Indiana Univ. Sch. of Med. and Richard L.
Roudebush VA Med. Ctr.
ANATOMY SUNDAY
149
S
U
N
537. NEUROBIOLOGY: NEUROPROTECTION AND
NEUROIMMUNOLOGY
Poster
s
un
. 7:30
am
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C
onvention
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Presentation time: 12:30
pm
-2:00
pm
A361
537.1
In response to damage-activated microglia
enhance neuronal differentiation and survival.
J. Chen and A.
Shibata. Creighton Univ.
A362
537.2
Ameliorative role of alpha lipoic acid in sodium
arsenite induced neurotoxicity in developing rat cerebellum.
P.
Dhar, P. Kaushal and R.D. Mehra. All India Inst. of Med. Sci.,
New Delhi.
A363
537.3
Taurine protection against endoplasmic
reticulum stress in an animal stroke model of cerebral artery
occlusion and stroke related conditions in primary neuronal
cell culture.
P. MohammadGharibani, J. Modi, J. Menzi, H.
Prentice and J.Y. Wu. Florida Atlantic Univ.
A364
537.4
Ethanol downregulates microglia inflammatory
responses augmented by endoplasmic reticulum stress.
J.
Goral and A. Meyer. Midwestern Univ., IL.
Biochemistry and Molecular Biology
538. GENOME REPLICATION AND REPAIR
Poster
s
un
. 7:30
am
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C
onvention
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Presentation time: 12:25
pm
-1:55
pm
C1
538.1
Investigating the regulation of DNA replication
origin licensing during cellular quiescence.
K.E. Coleman,
F. Yan, B. Major and J.G. Cook. Univ. of North Carolina at
Chapel Hill.
C2
538.2
Single molecular analysis of the encounter of
replication forks with DNA interstrand crosslinks.
J. Huang,
S. Liu, Y. Wang, A.K. Thazhathveetil, W. Wang and M.M.
Seidman. NIA, NIH, Baltimore, Univ. of California, Riverside
and Northwestern Univ.
C3
538.3
UmuD participates in a primitive DNA damage
checkpoint by interacting with DNA pol III
a and SSB. M.C.
Silva, K.R. Chaurasiya, C. Ruslie, L. Voortman, E.A. Ronayne,
P. Nevin, S. Lone, M. Chan, M.C. Williams and P.J. Beuning.
Northeastern Univ. and Bridgewater State Univ.
C4
538.4
Interplay of DNA polymerase lambda,
protection of telomeres 1 and TERRA in telomere elongation.
G. Maga, J. Lingner and U. Hübscher. Inst. of Molec. Genet.,
CNR, Pavia, Fed. Polytech. Sch. of Lausanne and Univ. of
Zürich-Irchel.
C5
538.5
Investigation of the pre-sensor 1 hairpin in
minichromosome maintenance proteins 2-7.
S.K.W. Lam, T.
Sing, C.J. Brandl and M.J. Davey. Univ. of Western Ontario
and Univ. of Toronto.
C6
538.6
Sequence analysis of PTEN in Castanea
dentata and PINK1 in Caenhorabditis elegans.
T.L. DeGennaro,
M.M. Dwyer, M.E. Gallagher, R. Korolyshun, O.E. Riccardi
and M.J. Paolella. Sacred Heart Acad., Hamden, CT.
C7
538.7
A single residue unique to DinB-like proteins
limits formation of the Pol IV multi-protein complex in
Escherichia coli.
T.M. Cafarelli, T.J. Rands, R.W. Benson, P.A.
Rudnicki, I. Lin and V.G. Godoy. Northeastern Univ.
539. MECHANISM AND CONTROL OF REPLICATION
INITIATION
Poster
s
un
. 7:30
am
—B
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C
onvention
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Presentation time: 12:25
pm
-1:55
pm
C8
539.1
Inhibition of pokeweed antiviral protein by
turnip mosaic virus genome-linked protein.
A. Domashevskiy
and D.J. Goss. John Jay Col. of Criminal Justice, Grad. Ctr.,
CUNY and Hunter Col., CUNY.
C9
539.2
Modulation of Mcm2-7 activity by Cdt1.
L.F.
DaSilva, T. Kolaczyk, X. Ma and M.J. Davey. Univ. of Western
Ontario.
C10
539.3
RNA polymerase primed DNA synthesis in
T7 bacteriophage system.
D. Nandakumar and S.S. Patel.
UMDNJ, Piscataway.
540. DNA ENZYMES
Poster
s
un
. 7:30
am
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onvention
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Presentation time: 12:25
pm
-1:55
pm
C11
540.1
DNA mismatch synthesis complexes
provide insights into base selectivity.
S. Xia, J. Wang and W.
Konigsberg. Yale Univ.
C12
540.2
DNA polymerase phylogeny recapitulates
virioplankton biology.
H.F. Schmidt, E.G. Sakowski, S.J.
Williamson, S.W. Polson and K.E. Wommack. Univ. of
Delaware and Lake Pend Oreille Waterkeeper, Sandpoint, ID.
C13
540.3
SAMHD1, a new actor in the regulation of
DNA precursors in mammalian cells.
V. Bianchi, E. Franzolin,
C. Rampazzo, P. Ferraro, C. Miazzi, G. Pontarin and P.
Reichard. Univ. of Padua.
C14
540.4
Dead DNA transport: a mutational analysis of
a competence helicase/translocase.
S.S. Chilton and B.M.
Burton. Harvard Univ.
SUNDAY ANATOMY/BIOCHEMISTRY
150
541. DNA REPLICATION MECHANISMS
Poster
s
un
. 7:30
am
—B
oston
C
onvention
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a-B
Presentation time: 12:25
pm
-1:55
pm
C15
541.1
Conformational analysis of processivity clamps
demonstrates that tertiary structure does not correlate with
structural dynamics.
P. Nevin, J. Fang, J.R. Engen and P.J.
Beuning. Northeastern Univ.
C16
541.2
Probing the nucleic acid binding modes of
the single-stranded DNA binding protein of the bacteriophage
T4 replication complex.
D. Jose, S.E. Weitzel and P.H. von
Hippel. Inst. of Molec. Biol., Eugene, OR.
C17
541.3
Successful computational prediction of
active site and distal residues essential for function in DNA
polymerase III alpha subunit.
R. Parasuram, P.J. Beuning and
M.J. Ondrechen. Northeastern Univ.
C18
541.4
Regulation of origin activation during
Drosophila follicle cell gene amplification.
B. Hua, S. Li, J.C.
Kim and T.L. Orr-Weaver. Whitehead Inst., Cambridge, MA.
C19
541.5
Structure-functional study of proteins that
regulate cell proliferation and differentiation.
G. Zhu and B.
Zhou. The Hong Kong Univ. of Sci. and Tech.
C20
541.6
Differential replication fork progression during
Drosophila follicle cell gene amplification.
J.L. Alexander and
T.L. Orr-Weaver. Whitehead Inst. for Biomed. Res. and MIT.
C21
541.7
Consistent mutations in type II topoismerases
of Vibrio cholerae O1 and global reduction in fluoroquinolone
susceptibility.
P. Kumar, D.N. Bhatt, N.C. Sharma, M. Jain,
D.K. Mishra, A.K. Goel and P.K. Yadava. Sch. of Life Sci.,
Jawaharlal Nehru Univ., M.V.I.D.H., New Delhi and D.R.D.E.,
Gwalior, India.
542. GENOME STABILITY AND DNA REPAIR
Poster
s
un
. 7:30
am
—B
oston
C
onvention
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a-B
Presentation time: 12:25
pm
-1:55
pm
C22
542.1
RECQL5 plays both co-operative and
complementary roles with WRN syndrome helicase.
V. Popuri,
J. Huang, R. Mahesh, T. Tadokoro, C.L. Deborah and V.A.
Bohr. NIA, NIH, Baltimore.
C23
542.2
Postmortem time affects the integrity of DNA
exracted from the brain and kidney of male albino Sprague
Dawley rats.
A.O. Ebuehi, A. Balogun, A. Fowora, O. Ebuehi,,
T. Amode and G. Ojieh. Univ. of Lagos, Nigeria.
C24
542.3
Biochemical analysis of S. cerevisiae Msh2-
Msh3 activity in triplet nucleotide repeat expansion.
X. Yu, S.
Sawant and M. Hingorani. Wesleyan Univ.
C25
542.4
The ATPase cycle of the tail-anchored protein
chaperone Get3.
M. Rome and S-o. Shan. Caltech.
C26
542.5
Investigating the properties of a repair
replication-fork in the budding yeast Saccharomyces cerevisiae.
R.P. Anand and J.E. Haber. Brandeis Univ.
C27
542.6
PCNA tyrosine phosphorylation by EGFR
promotes genome instability.
J. Ortega, J. Li, M. Ensor and
L. Gu. Univ. of Kentucky and Paul Laurence Dunbar H.S.,
Lexington.
C28
542.7
Role of the recombination enhancer in mating-
type switching in budding yeast.
A. Mehta and J. Haber.
Brandeis Univ.
C29
542.8
Disruption of de novo mitochondrial thymidylate
synthesis increases mtDNA content.
J.R. Alonzo and P.J.
Stover. Cornell Univ.
C30
542.9
Investigation of the functions of new
genes involved in repair of DNA double-strand breaks in
Saccharomyces cerevisiae.
B.A. Sanderson and L.K. Lewis.
Texas State Univ.-San Marcos.
C31
542.10 Functional characterization of Dbf4 interactions
with DNA replication and checkpoint factors.
D.R. Jones, L.A.
Matthews, B.J. McConkey, A. Guarné and B.P. Duncker.
Univ. of Waterloo and McMaster Univ., Canada.
C32
542.11 Localization to the nuclear pore complex
is required to prevent trinucleotide repeat instability.
X. Su,
V. Dion, S. Gasser and C. Freudenreich. Tufts Univ. and
Friedrich Miescher Inst., Basel.
C33
542.12 Interconverting conformations of slipped-DNA
junctions formed by trinucleotide repeats affect repair outcome.
M. Slean, K. Reddy, B. Wu, K. Nichol Edamura, M. Kekis,
F. Nelissen, R. Aspers, M. Tessari, O. Schärer, S. Wijmenga
and C. Pearson. Univ. of Toronto, Radboud Univ. Nijmegen,
Netherlands and Stony Brook Univ.
C34
542.13 Characterization of the role of Srs2 human
orthologs in triplet repeat maintenance.
J. Nguyen and C.
Freudenreich. Tufts Univ.
C35
542.14 Evidence of functional interactions between
the
a-subunit of Pol III and Pol IV (DinB) in Escherichia coli.
R.W. Benson, T.J. Rands and V.G. Godoy. Northeastern Univ.
C36
542.15 Sex-specific microRNA networks in cardiac
hypertrophy.
T. Burton, P. Malone, A. Baute and R. Waikel.
Eastern Kentucky Univ.
543. INHIBITORS OF DNA TRANSACTIONS
Poster
s
un
. 7:30
am
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Presentation time: 12:25
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-1:55
pm
C37
543.1
Identification and characterization of novel small
molecule inhibitors of the human Y-family DNA polymerases.
A.
Ketkar, M.K. Zafar, L. Maddukuri, N.R. Penthala, P. Crooks,
G.E. Coggins, R.S. Lloyd and R.L. Eoff. Univ. of Arkansas for
Med. Sci., Vanderbilt Univ. and Oregon Hlth. & Sci. Univ.
544. NUCLEOSOME AND CHROMATIN ASSEMBLY
Poster
s
un
. 7:30
am
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oston
C
onvention
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Presentation time: 12:25
pm
-1:55
pm
C38
544.1
Functional interplay of histone H1
phosphorylation and methylation.
L-J. Juan. Acad. Sinica,
Taipei.
C39
544.2
Structural and functional studies of the histone
chaperone Hif1, a component of the Hat1 chromatin assembly
complex.
M.J. Bagley and R.N. Dutnall. Univ. of San Diego.
BIOCHEMISTRY SUNDAY
151
S
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C40
544.3
Probing the histone binding requirements of
the Hif1 histone chaperone, a component of the Hat1 chromatin
assembly complex.
S. Szabo and R.N. Dutnall. Univ. of San
Diego.
545. SIGNALING RESPONSES TO DNA DAMAGE
Poster
s
un
. 7:30
am
—B
oston
C
onvention
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Presentation time: 12:25
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-1:55
pm
C41
545.1
Cisplatin-induced apoptosis in HeLa cells to
determine potential mechanisms for drug resistance.
M.M.
Shipley and A.J. Piefer. Hartwick Col., NY.
C42
545.2
The DNA damage checkpoint triggers
autophagy to regulate the initiation of anaphase.
V.V. Eapen,
F.J. Dotiwala, J.C. Harrison, A.A. Eden, V. Ranade, S.
Yoshida and J.E. Haber. Brandeis Univ.
C43
545.3
Pyrimidine dimer glycosylase mediated repair
of ultraviolet-induced mtDNA damage.
M.J. Calkins, R.S.
Lloyd and A.K. McCullough. Oregon Hlth. & Sci. Univ.
546. TELOMERES AND TELOMERASE
Poster
s
un
. 7:30
am
—B
oston
C
onvention
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Presentation time: 12:25
pm
-1:55
pm
C44
546.1
A role of heterogeneous nuclear
ribonucleoprotein A/Bs in telomere maintenance.
T-C.V. Wang
and P-R. Huang. Chang Gung Univ., Taiwan.
C45
546.2
A potential role for LIM protein Ajuba in
repression of DNA damage response in human cells.
S. Kalan,
A. Matveyenko and D. Loayza. Hunter Col., CUNY and CUNY
Grad. Ctr.
547. TRANSCRIPTION MECHANISMS
Poster
s
un
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
pm
-2:35
pm
C46
547.1
Bortezomib inhibits expression of
immunosuppressive cytokines IL-10 and TGF
b in cutaneous T
cell lymphoma.
T-P. Chang, S. Sanacora, S. Manna, B. Singha
and I. Vancurova. St. John’s Univ.
C47
547.2
The X-ray crystal structure of Escherichia coli
RNA polymerase
s
70
holoenzyme.
K. Murakami. Penn State.
C48
547.3
Structure-switching biosensors for the
quantitative measurement of protein:protein interactions
involved in aberrant transcriptional activity.
A.J. Bonham.
Metropolitan State Univ. of Denver.
C49
547.4
Regulation of VEGF expression in hypoxic
pulmonary artery endothelial cells by base excision DNA repair
(BER) activity.
V. Pastukh, G. Bardwell, V. Pastukh and M.
Gillespie. Univ. of South Alabama.
C50
547.5
Inhibition of GSK-3 activates CREB
transcriptional targets during induction of cardiomyocyte
hypertrophy.
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