T.J. Kalogeris, M. Wang and R.J. Korthuis. Univ. of
Missouri-Columbia.
B46
682.8
Hypoxia preconditioning lowers myocardial
matrix metalloproteinase activity.
L. Gonzalez, J. Estrada, R.T.
Mallet, H.F. Downey and J.L. Caffrey. Univ. of North Texas
Hlth. Sci. Ctr.
B47
682.9
Deleterious effect of acute administration of
nitric oxide donor GSNO on cardiac ischemia reperfusion injury
in a consomic rat model.
Q. Cheng, D. Nabor, D. Stowe, M.
Bienengraeber, J. Lazar and M. Riess. Med. Col. of Wisconsin
and VA Med. Ctr.
B48
682.10 Renal ischemia-reperfusion injury induces
a rapid activation of local inflammatory markers and causes
increased peritubular permeability.
O. Tenstad, L.M. Bivol,
B.M. Iversen, M. Hultström, R.K. Reed and H. Wiig. Univ. of
Bergen, Norway.
B49
682.11 Role of the angotensin II type 2 receptor in
thyroid hormone-induced cardiac hypertrophy in a model of
ischemia/reperfusion.
I.B. Silva, R.S. Santos and M.L.M.
Barreto-Chaves. Univ. of São Paulo and Fed. Univ. of Minas
Gerais, Brazil.
B50
682.12 Redox-dependent hepatocyte TNF
a secretion
following reoxygenation injury.
N.Y. Spencer, W. Zhou, Q. Li, Y.
Zhang, D. Abbott, B. Banfi and J.F. Engelhardt. Univ. of Iowa.
B51
682.13 Determining the mechanism of inhibition
of mitochondrial Ca
2+
overload by the cocoa flavanol
(-)-epicatechin as a means of conferring cardioprotection
during ischemia-reperfusion.
A. Herrera , J. Echeverri, P.
Khan and K. Yamazaki. California State Univ., Los Angeles.
683. INSTRUMENTATION, METHODOLOGY, AND
EXPERIMENTAL MODELS
Poster
(Sponsored by: The Microcirculatory Society)
s
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. 7:30
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Presentation time: 12:45
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B52
683.1
Helium ion microscopy of the rodent kidney
and male reproductive tract.
T.G. Paunescu, C. Huynh, L.
Lechner, B. Goetze, L. Stern, S. Breton and D. Brown.
Massachusetts Gen. Hosp., Harvard Med. Sch. and Carl Zeiss
Microscopy LLC, Peabody, MA.
B53
683.2
Validity, intra- and inter-test reliability of arterial
stiffness and wave reflection measured by the new brachial
cuff SphygmoCor Xcel.
M-H. Hwang, J-K. Yoo, H-K. Kim, C-L.
Hwang, K. Mackay, O. Hemstreet, E. Vasconez, K. Jacobs,
W.W. Nichols and D.D. Christou. Univ. of Florida.
PHYSIOLOGY SUNDAY
203
S
U
N
B54
683.3
High performance temperature and pressure
telemetry for rodents.
T.M. Clark, H. Millar, M. Lim, D.
McCormick, D. Russell, S-J. Guild, S. Malpas, P. Hu, B. Pauly
and D. Budgett. Univ. of Auckland and Millar Instruments,
Auckland, New Zealand.
B55
683.4
Recording of intracranial pressure in conscious
rats via telemetry.
S-J. Guild, D. McCormick, M. Lim, B. Pauly,
R. Kirton, D. Budgett, M. Kondo, E. Stehlin, C.J. Barrett
and S.C. Malpas. Univ. of Auckland, New Zealand and Millar
Instruments, Houston and Auckland.
B56
683.5
Localization of fluorescent particles with
nanometer precision using standard microscopy and a point
spread function approach.
A. Marki, E. Ermilov, T.W. Secomb
and A.R. Pries. Charité Med. Univ., Berlin and Univ. of Arizona.
B57
683.6
Novel model of thermoregulation based on
control theory used to evaluate peripheral microvascular
function.
V. Chekh, P. Soliz, S. Barriga, E. McGrew, N. Kanagy
and S. Luan. Univ. of New Mexico and VisionQuest Biomed.
LLC, Albuquerque.
B58
683.7
Relations of aortic pulse wave velocity and
augmentation index assessed by the new brachial cuff
SphygmoCor Xcel with other arterial stiffness measures.
C-L.
Hwang, M-H. Hwang, J-K. Yoo, H-K. Kim, K.R. Mackay, O.
Hemstreet, E. Vasconez, K. Jacobs, W.W. Nichols and D.D.
Christou. Univ. of Florida.
684. INFLAMMATION/LEUKOCYTE-ENDOTHELIUM
INTERACTION
Poster
(Sponsored by: The Microcirculatory Society)
s
un
. 7:30
am
—B
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C
onvention
& e
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C
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Presentation time: 12:45
pm
-3:00
pm
B59
684.1
Effect of acute moderate exercise on
vaccination induced inflammation and arterial function in older
adults.
S.M. Ranadive, R.M. Kappus, H. Yan, A.D. Lane, M.D.
Cook, J.A. Woods, K.W. Wilund, V. Vanar and B. Fernhall.
Mayo Clin., Univ. of Illinois at Chicago at Chicago and Univ. of
Illinois at Urbana-Champaign.
B60
684.2
Activation of NLRP3 inflammasome in alveolar
macrophages mediates mechanical stretch-induced lung
inflammation.
J. Wu, Z. Yan, A. Malik, D. Schwartz, J. Yu and
G. Hu. Univ. of Illinois at Chicago, Qilu Hosp. of Shandong
Univ., China.
B61
684.3
The in vivo effects of glucose and lipid on the
granulocytes and monocytes of type 2 diabetic male subjects.
P. Horvath, S.R. Oliver, F.P. Zaldivar, S. Radom-Aizik and
P.R. Galassetti. Univ. of California, Irvine.
B62
684.4
Renin/prorrenin receptor expression on
leukocytes associated with an experimental model of
preeclampsia.
E. Sanchez-Guerrero, M.E. Hernandez-
Campos, M.I. Trinidad-Gomez and P. Lopez-Sanchez. IPN-
Med. Sch., Mexico City.
B63
684.5
Endothelial and leukocyte interactions in
oxidative stress.
J. Chen and M. Kavdia. Wayne State Univ.
B64
684.6
Vascular SOD levels is more important than
leukocyte transmigration and smooth muscle cell activation on
vascular pathology.
S. Kar and M. Kavdia. Wayne State Univ.
B65
684.7
Effects of gender and race on interleukin-6
production in response to CRP in HUVECs.
C. Ling, J.
Kretzschmar, H. Grimm and M. Brown. Univ. of Illinois at
Chicago.
B66
684.8
Increased circulating microparticles in diabetic
rats are not only a result of cell activation but actively serve as
mediators of inflammatory signaling.
C. Stork and P. He. West
Virginia Univ.
685. ANGIOGENESIS/MICROVASCULAR
REMODELING/INJURY AND REPAIR
Poster
(Sponsored by: The Microcirculatory Society)
s
un
. 7:30
am
—B
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C
onvention
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C
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Presentation time: 12:45
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-3:00
pm
B67
685.1
Early protective joint motion influences gene
expression in a rat model of anterior cruciate complete rupture.
T. Kokubun, N. Kanemura, H. Maejima, T. Fujino, S. Morita
and K. Takayanagi. Saitama Prefect. Univ., Teikyo Univ. of Sci.,
Urawa Orthopead., Japan and Tokyo Med. and Dent. Univ.
B68
685.2
Impact of redox signaling inhibition on collateral
growth in young, healthy rats.
S.J. Miller, M. Wenning, R.G.
Bills, P. Sliva, C.A. Labarrere, M.R. Kelley, M.L. Fishel
and J.L. Unthank. Indiana Univ. and Methodist Res. Inst.,
Indianapolis.
B69
685.3
High salt diet suppresses the angiogenic
competency of bone marrow mononuclear cells.
J.R. Karcher
and A.S. Greene. Med. Col. of Wisconsin.
B70
685.4
Anti-angiogenic factors of tissue-engineered
oral mucosal epithelial cell sheets for corneal regeneration.
F.
Bardag-Gorce, J. Oliva Vilana, A. Wood, A. Makalinao, D.
Pan, H. Sota and Y. Niihara. LA BioMed at Harbor UCLA.
B71
685.5
Homocysteine disrupts actin organization and
vascular outgrowth by an iNOS-dependent mechanism during
angiogenesis.
J.N. Mayo, C-H. Chen and S.E. Bearden. Idaho
State Univ.
B72
685.6
Both Kdr and Flt1 play a vital role in
hypoxia-induced Src-PLD1-PKC
g-cPLA2 activation and
retinal neovascularization.
N.K. Singh, D.E. Hansen III, V.
Kundumani-Sridharan and G.N. Rao. Univ. of Tennessee
Hlth. Sci. Ctr., Memphis.
B73
685.7
Vascular endothelial growth factor-A signaling
in bone marrow-derived endothelial progenitor cells exposed to
hypoxia.
B.R. Hoffmann, J.R. Wagner, A.R. Prisco and A.S.
Greene. Med. Col. of Wisconsin.
B74
685.8
Monocyte recruitment during microvascular
arteriogenesis is induced by altered flow and influenced by
proximity of venules to collateral arterioles.
A. Bruce, J.K.
Meisner, R.J. Price and S.M. Peirce. Univ. of Virginia.
B75
685.9
Connexin43 modulates endothelial wound
healing, cell proliferation and locomotion.
C-H. Chen, J.N.
Mayo and S.E. Bearden. Idaho State Univ.
B76
685.10 20-HETE induces remodeling of renal
resistance arteries independent of blood pressure elevation in
androgen-induced hypertension.
Y. Ding, C-C. Wu, V. Garcia,
I. Dimitrova, A. Weidenhammer, F. Zhang, J. Falck, S. Mei, J.
Capdevila and M.L. Schwartzman. New York Med. Col., Univ.
of Texas Southwestern Med. Ctr. and Vanderbilt Univ. Med. Sch.
SUNDAY PHYSIOLOGY
204
B77
685.11 TRPV4 channel activation inhibits tumor
endothelial cell proliferation and migration via modulation of
ERK1/2 pathway.
R. Thoppil, R.K. Adapala, S. Cotman, S.
Paruchuri, W.M. Chilian, J.G. Meszaros and C.K. Thodeti.
Northeast Ohio Med. Univ. and Univ. of Akron.
B78
685.12 Identification of morphological and
hemodynamic biomarkers for tumor vascular perfusion through
mathematical modeling and high-resolution imaging.
S.K.
Stamatelos, E. Kim, A.P. Pathak and A.S. Popel. Johns
Hopkins Sch. of Med.
B79
685.13 Untangling tumor vasculature. G. Gruionu, D.
Bazou and J. Song. Massachusetss Gen. Hosp. and Harvard
Med. Sch., Charlestown.
B80
685.14 A potential role for autocrine VEGF signaling
in endothelial cell function.
E. Nwadozi, C. Uchida, E. Gee,
S.T.K. Liu and T.L. Haas. York Univ., Canada.
B81
685.15 Regulation of exercise-induced endothelial
sprout formation by FoxO1/3/4.
S.T.K. Liu, D. Slopack, E.
Roudier and T.L. Haas. York Univ., Canada.
B82
685.16 Role of FoxO within the microvasculature of the
skeletal muscle in diet-induced obesity.
E.A. Roudier, K. Alim,
V. Vu, Y. Liu, O. Birot and G. Sweeney. York Univ., Canada.
B83
685.17 Vascular islands increase during microvascular
network regression and proliferate during angiogenesis.
M.R.
Kelly-Goss, R.S. Sweat and W.L. Murfee. Tulane Univ.
B84
685.18 The impact of outward remodeling on
vasodilation in skeletal muscle resistance arteries.
R. Gallagher
and T.R. Cardinal. Cal Poly State Univ., San Luis Obispo.
B85
685.19 COMP-Ang1 prevents structural and functional
damage of the retina in a mouse model of central retinal artery
occlusion.
P.R. Olson, J.M. Cahoon, M.M. Flood, X.H. Zhang
and B.K. Ambati. Univ. of Utah.
B86
685.20 Skeletal muscle remodeling in myofiber VEGF-
deficient exercise trained mice.
H. Delavar, B. Rich, P.D.
Wagner and E.C. Breen. UCSD.
B87
685.21 Functional vasodilation is impaired in
arterialized capillaries following ischemia.
J.P. Cutts, F.
MacGabhann and T. Cardinal. Cal Poly San Luis Obispo and
Johns Hopkins Univ.
B88
685.22 Tumor cell interaction with sprouting blood
vessels in 3D microfluidic platform.
S.I. Ahn, S. Song and J.H.
Shin. KAIST, Daejeon, South Korea.
686. ATHEROSCLEROSIS/THROMBOSIS/PLATELETS
Poster
(Sponsored by: The Microcirculatory Society)
s
un
. 7:30
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Presentation time: 12:45
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-3:00
pm
B89
686.1
The pro-atherosclerotic mechanism of
lysosomal-free cholesterol accumulation in CD38,
-/-
macrophages.
F. Zhang and P-L. Li. Virginia Commonwealth
Univ.
B90
686.2
Differential role of complement 5a receptor
in microvascular thrombosis in two models of experimental
sepsis.
R. Stark and R. Rumbaut. Baylor Col. of Med. and
Michael E. DeBakey VA Med. Ctr.
B91
686.3
Elevation of extracellular NaCl increases
secretion of von Willebrand factor from endothelial cells.
N.I.
Dmitrieva and M.B. Burg. NHLBI, NIH.
B92
686.4
Non-invasive theranostic to predict and
assess response to atherosclerotic drugs.
A.J. Buckler, J.A.
Hamilton, A. Madabhushi and J.C. Keith. vascuVis Inc.,
Wenham, MA, Boston Univ., Case Western Reserve Univ. and
Keith Pharmacol. Res. Gp., Andover, MA.
B93
686.5
The effect of advanced glycation end products
on endothelial cell and platelet activation and their interactions.
Z. Maria, W. Yin and D.A. Rubenstein. Oklahoma State Univ.
B94
686.6
Anti-aggregatory effects of sulforaphane on in
vitro platelet function.
S. Gillespie, A. O’Malley, A. Solomon,
M. Emerson and F. Gavins. Imperial Col. London.
B95
686.7
Blood platelet insulin sensitivity in atherogenic
dieted rabbits fed fish oils with comparable eicosapentanoic
acid content.
E.L. Beard, S.E. Skelly and B.M. Bergens.
Loyola Univ. New Orleans.
B96
686.8
High dietary fat intake does not influence
endothelial fibrinolytic function in older adults.
J. Greiner, B.
Stauffer and C. DeSouza. Univ. of Colorado Boulder.
B97
686.9
Aquaporin 1 does not contribute to the
progression of abdominal aortic aneurysm in mice.
J. Stubbe,
S.H. Johansen, P.B.L. Hansen, P. Bie and B.L. Jensen. Univ.
of Southern Denmark.
B98
686.10 Alterations in the nitric oxide/soluble guanylyl
cyclase pathway enhance the risk of myocardial infarction.
C.
de Wit, F. Kaiser, Z. Aherrahrou, D. Koesling, H. Schunkert
and J. Erdmann. Univ. of Lübeck, Ruhr Univ. Bochum and
Tech Univ. Munich, Germany.
B99
686.11 Reversal of ATP-induced NLRP3
inflammasome activation and lipids deposition in macrophages
from mice lacking apoptosis-associated speck-like protein
(ASC) gene.
X. Li, Y. Zhang, M. Xia, K.M. Boini and P-L. Li.
Virginia Commonwealth Univ.
B100
686.12 Short sleep duration and endothelial t-PA
release in overweight/obese adults.
T.D. Bammert, C.A.
Beckstrom, J.J. Greiner, B.L. Stauffer and C.A. DeSouza.
Univ. of Colorado Boulder.
B101
686.13 Use of platelet proteomic profiles to distinguish
platelets activated by different agonists.
W. Yin, S.K.
Shanmugavelayudam and D.A. Rubenstein. Oklahoma
State Univ.
B102
686.14 Dematin binds to F-actin filaments in activated
platelets.
A.C. Azim and A. Hill. Chicago State Univ.
687. MICROCIRCULATION I
Poster
s
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. 7:30
am
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C
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Presentation time: 12:45
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-3:00
pm
B103
687.1
Ca
2+
-activated K
+
channels of small and
intermediate conductance control the activation of endothelial
cell connexin- and pannexin-formed hemichannels.
M. Lillo, P.
Gaete, M. Puebla and X. Figueroa. Pontifical Catholic Univ. of
Chile.
B104
687.2
Nitric oxide-mediated vasodilation is controlled
by pannexin-1-formed channels.
M. Puebla, P. Gaete, M. Lillo
and X. Figueroa. Pontifical Catholic Univ. of Chile.
B105
687.3
BK channels are not involved in the ryanodine-
induced vasoconstriction of the spiral modiolar artery.
G.
Krishnamoorthy, K. Reimann and P. Wangemann. Kansas
State Univ.
PHYSIOLOGY SUNDAY
205
S
U
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B106
687.4
Acute ischemia activates distinct ion currents
in endothelial cells and pericytes of capillaries in guinea pig
cochlear lateral wall.
Y. Yang, A.L. Nuttall and Z-G. Jiang.
Oregon Hlth. & Sci. Univ.
B107
687.5
Ischemic treatment hyperpolarizes cochlear
arteriolar smooth muscle and endothelial cells via different
channel mechanisms.
Z-G. Jiang and Y. Yang. Oregon Hlth. &
Sci. Univ.
B108
687.6
Distinct potentials in the myoendothelial
junction.
J.C. Brasen and N-H. Holstein-Rathlou. Univ. of
Copenhagen.
B109
687.7
Impaired vasodilation of human obese visceral
resistance arteries is improved by apocynin through hydrogen
peroxide and activation of SK and IK channels.
J-T. Bian, M.
Szczurek, A.T. Robinson and S.A. Phillips. Univ. of Illinois at
Chicago.
B110
687.8
Experimental diabetes impairs endothelial IK
Ca
channel function in uteroplacental arteries from pregnant rats.
N.I. Gokina, J.K. Phillips, A.D. Bonev, A.P. Gokin and G.
Goloman. Univ. of Vermont.
B111
687.9
EDHFs contribute to ACh-mediated
vasodilation in human skin in a dose-dependent manner.
V.E.
Brunt, N. Fujii and C.T. Minson. Univ. of Oregon.
B112
687.10 Nutrient overload causes rapid accumulation
of myeloperoxidase in the mesenteric fat.
K. Preston, I. Rom
and R. Scalia. Temple Univ. Sch. of Med.
B113
687.11 Mitochondrial reactive oxygen species
contribute to impaired flow-induced dilation in visceral but not
subcutaneous adipose tissue resistance arteries in human
obesity.
A.T. Robinson, M. Szczurek, J-T. Bian, A. Cavka, I.
Grizelj and S. Phillips. Univ. of Illinois at Chicago and Univ. of
Osijek, Croatia.
B114
687.12 Role of hydrogen peroxide and
epoxyeicosatrienoic acids in arachidonic acid-induced dilation
of human coronary arterioles.
N.S. Zinkevich, D.D. Gutterman
and D.X. Zhang. Med. Col. of Wisconsin and Carroll Univ.
B115
687.13 Functional capillary recruitment during
cephalic phase of digestion is blunted in obesity.
C. Buss, L.G.
Kraemer-Aguiar, P.A. Maranhão and E. Bouskela. State
Univ. of Rio de Janeiro.
B116
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