Aura 2016 Supplementary data


Table S3.8 Prevalence of antimicrobial use and infection in residential aged care facilities, by jurisdiction, remoteness and provider type, 2015



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Table S3.8 Prevalence of antimicrobial use and infection in residential aged care facilities, by jurisdiction, remoteness and provider type, 2015


Measure

Category

Number of facilities

Number of beds audited

Prevalence of antimicrobial use, n (%)

Prevalence of infection, n (%)

State

New South Wales

17

545

66 (12.1)

32 (5.9)

State

Queensland

7

481

31 (6.4)

17 (3.5)

State

South Australia

8

559

99 (17.7)

53 (9.5)

State

Tasmania

6

147

19 (12.9)

9 (6.1)

State

Victoria

130

4704

334 (7.1)

172 (3.7)

State

Western Australia

18

1153

310 (26.9)

61 (5.3)

Remoteness

Major cities

51

2881

397 (13.8)

127 (4.4)

Remoteness

Inner regional

81

3323

312 (9.4)

148 (4.5)

Remoteness

Outer regional

45

1245

123 (9.9)

50 (4.0)

Remoteness

Remote

8

128

25 (20.0)

17 (13.6)

Remoteness

Very remote

1

12

2 (16.7)

2 (16.7)

Provider type

Not for profit

37

2181

426 (19.5)

120 (5.5)

Provider type

Government

141

4963

395 (8.0)

207 (4.2)

Provider type

Private

8

445

38 (8.5)

17 (3.8)

National aggregate

na

186

7589

859 (11.3)

344 (4.5)

na = not applicable

Source: acNAPS, 2015


Table S3.9 World Health Organization defined daily doses for antibacterial agents included in the National Antimicrobial Utilisation Surveillance Program annual report

Table S3.9a J01A Tetracyclines


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01AA Tetracyclines

J01AA02

Doxycycline

0.1

O, P

J01AA Tetracyclines

J01AA08

Minocycline

0.2

O, P

J01AA Tetracyclines

J01AA12

Tigecycline

0.1

P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9b J01B Amphenicols


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01BA Amphenicols

J01BA01

Chloramphenicol

3

O, P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9c J01C β-lactam antibacterials, penicillins


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01CA Penicillins with extended spectrum 

J01CA01

Ampicillina

2

O, P

J01CA Penicillins with extended spectrum 

J01CA04

Amoxicillina

1

O, P

J01CE β-lactamase-sensitive penicillins 

J01CE01

Benzylpenicillina

3.6

P

J01CE β-lactamase-sensitive penicillins 

J01CE02

Phenoxymethylpenicillina

2

O

J01CE β-lactamase-sensitive penicillins 

J01CE08

Benzathine benzylpenicillina

3.6

P

J01CE β-lactamase-sensitive penicillins 

J01CE09

Procaine penicillina

0.6

P

J01CF β-lactamase-resistant penicillins 

J01CF01

Dicloxacillin

2

O, P

J01CF β-lactamase-resistant penicillins 

J01CF05

Flucloxacillin

2

O, P

J01CR Combinations of penicillins, including β-lactamase inhibitors

J01CR02

Amoxycillin and enzyme inhibitora

1

O

J01CR Combinations of penicillins, including β-lactamase inhibitors

J01CR03

Ticarcillin and enzyme inhibitorb

15

P

J01CR Combinations of penicillins, including β-lactamase inhibitors

J01CR05

Piperacillin and enzyme inhibitorb

14

P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

a Without antipseudomonal activity

b With antipseudomonal activity

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9d J01D Other β-lactam antibacterials


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01DB First-generation cephalosporins

J01DB01

Cefalexin

2

O

J01DB First-generation cephalosporins

J01DB03

Cefalotin

4

P

J01DB First-generation cephalosporins

J01DB04

Cefazolin

3

P

J01DC Second-generation cephalosporins 

J01DC01

Cefoxitin

6

P

J01DC Second-generation cephalosporins 

J01DC02

Cefuroxime

0.5

O

J01DC Second-generation cephalosporins 

J01DC04

Cefaclor

1

O

J01DD Third-generation cephalosporins 

J01DD01

Cefotaxime

4

P

J01DD Third-generation cephalosporins 

J01DD02

Ceftazidime

4

P

J01DD Third-generation cephalosporins 

J01DD04

Ceftriaxone

2

P

J01DE Fourth-generation cephalosporins 

J01DE01

Cefepime

2

P

J01DH Carbapenems 

J01DH02

Meropenem

2

P

J01DH Carbapenems 

J01DH51

Imipenem and enzyme inhibitor

2

P

J01DH Carbapenems 

J01DH03

Ertapenem

1

P

J01DH Carbapenems 

J01DH04

Doripenem

1.5

P

J01DF Monobactams

J01DF01

Aztreonam

4

P

J01DI Other cephalosporins

J01DI02

Ceftaroline

1.2

P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9e J01E Sulfonamides and trimethoprim


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01EA Trimethoprim and derivatives

J01EA01

Trimethoprim

0.4

O, P

J01EE Sulfonamides and trimethoprim

J01EE01

Sulfamethoxazole and trimethoprim

1.92

O, P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9f J01F Macrolides, lincosamides and streptogramins


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01FA Macrolides

J01FA01

Erythromycin

1

O, P

J01FA Macrolides

J01FA01

Erythromycin ethylsuccinate

2

O

J01FA Macrolides

J01FA06

Roxithromycin

0.3

O

J01FA Macrolides

J01FA09

Clarithromycin

0.5

O

J01FA Macrolides

J01FA10

Azithromycin

0.3

O

J01FA Macrolides

J01FA10

Azithromycin

0.5

P

J01FF Lincosamides

J01FF01

Clindamycin

1.2

O

J01FF Lincosamides

J01FF01

Clindamycin

1.8

P

J01FF Lincosamides

J01FF02

Lincomycin

1.8

O, P

J01FG Streptogramins

J01FG01

Pristinamycin

2

O

J01FG Streptogramins

J01FG02

Quinupristin/dalfopristin

1.5

P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9g J01G Aminoglycoside antibacterials


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01GB Other aminoglycosides

J01GB01

Tobramycin

0.24

P

J01GB Other aminoglycosides

J01GB01

Tobramycin

0.3

Inh solution

J01GB Other aminoglycosides

J01GB01

Tobramycin

0.112

Inh powder

J01GB Other aminoglycosides

J01GB03

Gentamicin

0.24

P

J01GB Other aminoglycosides

J01GB05

Neomycin

1

O

J01GB Other aminoglycosides

J01GB06

Amikacin

1

P

ATC = Anatomical Therapeutic Chemical; Inh = inhalation; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9h J01M Quinolone antibacterials


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01MA Fluoroquinolones

J01MA01

Ofloxacin (oral product not marketed in Australia but available through Special Access Scheme)

0.4

O

J01MA Fluoroquinolones

J01MA02

Ciprofloxacin

1

O

J01MA Fluoroquinolones

J01MA02

Ciprofloxacin

0.5

P

J01MA Fluoroquinolones

J01MA06

Norfloxacin

0.8

O

J01MA Fluoroquinolones

J01MA14

Moxifloxacin

0.4

O, P

ATC = Anatomical Therapeutic Chemical; O = oral; P = parenteral

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology


Table S3.9i J01X Other antibacterials


ATC code – chemical subgroup

ATC code

Generic name

Defined daily dose (grams)

Route

J01XA Glycopeptide antibacterials

J01XA01

Vancomycin

2

O, P

J01XA Glycopeptide antibacterials

J01XA02

Teicoplanin

0.4

P

J01XB Polymyxins

J01XB01

Colistin

3 MU

P, Inh

J01XC Steroid antibacterials

J01XC01

Fusidic acid

1.5

O, P

J01XD Imidazole derivatives

J01XD01

Metronidazole

1.5

P

J01XD Imidazole derivatives

J01XD01

Metronidazole

2

O, R

J01XD Imidazole derivatives

J01XD02

Tinidazole

2

O

J01XX Other antibacterials

J01XX08

Linezolid

1.2

O, P

J01XX Other antibacterials

J01XX09

Daptomycin

0.28

P

J04AB Antibiotics

J04AB02

Rifampicin

0.6

O, P

ATC = Anatomical Therapeutic Chemical; Inh = inhalation; MU = million units; O = oral; P = parenteral; R = rectal

Source: World Health Organization Collaborating Centre for Drug Statistics Methodology



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