Poster presentation
286
STUDY REACTION INTERACTION OF ACETOACET ETHER,
HOMOVERATRYLAMINES AND p-HYDROXYBEZALDEHYDE
A.A. Xudoyberdiyeva, S.B. Xolmatova, A. Sh Saidov
Sh. Samarkand State University named after Rashidov
For decades, the chemistry of heterocyclic compounds has been one of the most
important sciences in organic synthesis and pharmaceutical chemistry. In addition,
science and technology are moving to environmentally friendly and sustainable
processes. In this context, multi-component reactions have become one of the main
areas of synthetic organic chemistry. Compared to traditional methods, multicomponent
reactions show higher efficiency and diversity because of their selectivity and economy
of reaction steps, as well as the formation of carbon-carbon and carbon-heteroatom
bonds in one pot, as evidenced by the simplicity of the process. will give. Usually, the
purification of the products obtained as a result of multicomponent reactions is also
simple, since all organic reagents participate in the reaction process and are used for the
formation of the target products.
As
a
continuation
of
the
work,
we
dissolved
homoveratrylamine,
p-hydroxybenzaldehyde and acetylaceto in ethyl alcohol in a magnetic stirrer.
The progress of the reaction was monitored by thin-layer chromatography, and the
hexahydropyrimidinone derivative was synthesized as a result of the reaction.
The structure of the product was established on the basis of IR and NMR
spectroscopies.
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