TABLE OF CONTENTS
JANUARY 2016 • VOLUME 60 • NO. 1
CHALLENGING CLINICAL CASES IN ANTIMICROBIAL
RESISTANCE
Clinafloxacin for Treatment of Burkholderia cenocepacia
Infection in a Cystic Fibrosis PatientChallenging Clinical Case
Akshu Balwan, David P. Nicolau,
Minkey Wungwattana, Jonathan B.
Zuckerman, Valerie Waters
(Commentator)
1–5
CHEMISTRY; BIOSYNTHESIS
Synthesis, Bioactivity Evaluation, and Toxicity Assessment of
Novel Salicylanilide Ester Derivatives as Cercaricides against
Schistosoma japonicum and Molluscicides against Oncomelania
hupensis
Weisi Wang, Zhiqiang Qin, Dan Zhu,
Yufen Wei, Shizhu Li, Liping Duan
323–331
MECHANISMS OF ACTION: PHYSIOLOGICAL EFFECTS
Impact of a Cross-Kingdom Signaling Molecule of Candida
albicans on Acinetobacter baumannii Physiology
Xenia Kostoulias, Gerald L. Murray,
Gustavo M. Cerqueira, Jason B. Kong,
Farkad Bantun, Eleftherios Mylonakis,
Chen Ai Khoo, Anton Y. Peleg
161–167
Gallium Potentiates the Antibacterial Effect of Gentamicin
against Francisella tularensis
Helena Lindgren, Anders Sjöstedt
288 –295
Cardiac Effects of Echinocandins in Endotoxemic Rats
Christian Koch, Matthias Wolff,
Michael Henrich, Markus A. Weigand,
Christoph Lichtenstern, Florian Uhle
301–306
Penicillin Binding Protein 1 Is Important in the Compensatory
Response of Staphylococcus aureus to Daptomycin-Induced
Membrane Damage and Is a Potential Target for
-Lactam–Daptomycin Synergy
Andrew D. Berti, Erin Theisen,
John-Demian Sauer, Poochit Nonejuie,
Joshua Olson, Joseph Pogliano, George
Sakoulas, Victor Nizet, Richard A.
Proctor, Warren E. Rose
451– 458
Interactions of OP0595, a Novel Triple-Action
Diazabicyclooctane, with
-Lactams against OP0595-Resistant
Enterobacteriaceae Mutants
David M. Livermore, Marina Warner,
Shazad Mushtaq, Neil Woodford
554 –560
MECHANISMS OF RESISTANCE
Cooccurrence of Multiple AmpC
-Lactamases in Escherichia
coli, Klebsiella pneumoniae, and Proteus mirabilis in Tunisia
Thouraya Chérif, Mabrouka Saidani,
Dominique Decré, Ilhem Boutiba-Ben
Boubaker, Guillaume Arlet
44 –51
Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by
OXA-58 Class D
-Lactamase of Acinetobacter baumannii
Shivendra Pratap, Madhusudhanarao
Katiki, Preet Gill, Pravindra Kumar,
Dasantila Golemi-Kotra
75– 86
Genomic Characteristics of NDM-Producing Enterobacteriaceae
Isolates in Australia and Their bla
NDM
Genetic Contexts
Alexander M. Wailan, David L.
Paterson, Karina Kennedy, Paul R.
Ingram, Evan Bursle, Hanna E. Sidjabat
136 –141
Structural Basis of Metallo-
-Lactamase Inhibition by Captopril
Stereoisomers
Jürgen Brem, Sander S. van Berkel,
David Zollman, Sook Y. Lee, Opher
Gileadi, Peter J. McHugh, Timothy R.
Walsh, Michael A. McDonough,
Christopher J. Schofield
142–150
Continued on following page
Instructions to Authors are available at http://journalitas.asm.org/t/46519.
The Soil Microbiota Harbors a Diversity of Carbapenem-
Hydrolyzing
-Lactamases of Potential Clinical Relevance
Dereje Dadi Gudeta, Valeria Bortolaia,
Greg Amos, Elizabeth M. H.
Wellington, Kristian K. Brandt, Laurent
Poirel, Jesper Boye Nielsen, Henrik
Westh, Luca Guardabassi
151–160
Molecular Characterization of Carbapenem-Nonsusceptible
Enterobacterial Isolates Collected during a Prospective
Interregional Survey in France and Susceptibility to the Novel
Ceftazidime-Avibactam and Aztreonam-Avibactam
Combinations
Hervé Dupont, Olivier Gaillot, Anne-
Sophie Goetgheluck, Claire Plassart,
Jean-Philippe Emond, Marion Lecuru,
Nicolas Gaillard, Sarah Derdouri,
Baptiste Lemaire, Marion Girard de
Courtilles, Vincent Cattoir, Hedi
Mammeri
215–221
Activity of Isavuconazole and Other Azoles against Candida
Clinical Isolates and Yeast Model Systems with Known Azole
Resistance Mechanisms
Dominique Sanglard, Alix T. Coste
229 –238
Within-Host Selection of Drug Resistance in a Mouse Model of
Repeated Incomplete Malaria Treatment: Comparison between
Atovaquone and Pyrimethamine
Suci Nuralitha, Josephine E. Siregar,
Din Syafruddin, Jessica Roelands, Jan
Verhoef, Andy I. M. Hoepelman,
Sangkot Marzuki
258 –263
Role of Non-Active-Site Residue Trp-93 in the Function and
Stability of New Delhi Metallo-
-Lactamase 1
Asad U. Khan, M. Tabish Rehman
356 –360
Expression of Plasmodium vivax crt-o Is Related to Parasite
Stage but Not Ex Vivo Chloroquine Susceptibility
Zuleima Pava, Irene Handayuni,
Grennady Wirjanata, Sheren To, Leily
Trianty, Rintis Noviyanti, Jeanne Rini
Poespoprodjo, Sarah Auburn, Ric N.
Price, Jutta Marfurt
361–367
In Vitro Activity of
-Lactams in Combination with
-Lactamase Inhibitors against Multidrug-Resistant
Mycobacterium tuberculosis Isolates
Dan Zhang, Yufeng Wang, Jie Lu, Yu
Pang
393–399
Reactive Oxygen Species Contribute to the Bactericidal Effects of
the Fluoroquinolone Moxifloxacin in Streptococcus pneumoniae
M. J. Ferrándiz, A. J. Martín-Galiano,
C. Arnanz, T. Zimmerman, A. G. de la
Campa
409 – 417
Carriage of Enterobacteria Producing Extended-Spectrum
-Lactamases and Composition of the Gut Microbiota in an
Amerindian Community
María José Gosalbes, Jorge F. Vázquez-
Castellanos, Cécile Angebault,
Paul-Louis Woerther, Etienne Ruppé,
María Loreto Ferrús, Amparo Latorre,
Antoine Andremont, Andrés Moya
507–514
Plasmid-Mediated OqxAB Is an Important Mechanism for
Nitrofurantoin Resistance in Escherichia coli
Pak-Leung Ho, Ka-Ying Ng, Wai-U Lo,
Pierra Y. Law, Eileen Ling-Yi Lai, Ya
Wang, Kin-Hung Chow
537–543
Extracellular DNA Acidifies Biofilms and Induces
Aminoglycoside Resistance in Pseudomonas aeruginosa
Mike Wilton, Laetitia Charron-Mazenod,
Richard Moore, Shawn Lewenza
544 –553
Preservation of Acquired Colistin Resistance in Gram-Negative
Bacteria
Ji-Young Lee, Myung-Jin Choi, Hyeon
Jin Choi, Kwan Soo Ko
609 – 612
Novobiocin Inhibits the Antimicrobial Resistance Acquired
through DNA Damage-Induced Mutagenesis in Acinetobacter
baumannii
Luis M. Jara, María Pérez-Varela, Jordi
Corral, Marta Arch, Pilar Cortés,
Germán Bou, Jesús Aranda, Jordi Barbé
637– 639
Double Copies of bla
KPC-3
::Tn4401a on an IncX3 Plasmid in
Klebsiella pneumoniae Successful Clone ST512 from Italy
Daniela Fortini, Laura Villa, Claudia
Feudi, João Pires, Celestino Bonura,
Caterina Mammina, Andrea
Endimiani, Alessandra Carattoli
646 – 649
Complete Sequences of IncU Plasmids Harboring Quinolone
Resistance Genes qnrS2 and aac(6= )-Ib-cr in Aeromonas spp.
from Ornamental Fish
Hana Dobiasova, Petra Videnska,
Monika Dolejska
653– 657
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
Characterization of a cfr-Carrying Plasmid from Porcine
Escherichia coli That Closely Resembles Plasmid pEA3 from the
Plant Pathogen Erwinia amylovora
Rongmin Zhang, Bin Sun, Yang Wang,
Lei Lei, Stefan Schwarz, Congming Wu
658 – 661
Acquired Flucytosine Resistance during Combination Therapy
with Caspofungin and Flucytosine for Candida glabrata Cystitis
Caroline Charlier, Carine El Sissy,
Sophie Bachelier-Bassi, Anne Scemla,
Gilles Quesne, Emilie Sitterlé,
Christophe Legendre, Olivier
Lortholary, Marie-Elisabeth Bougnoux
662– 665
fosI Is a New Integron-Associated Gene Cassette Encoding
Reduced Susceptibility to Fosfomycin
Karla de Oliveira Pelegrino, Juliana
Coutinho Campos, Suely Carlos
Ferreira Sampaio, Karina Lezirovitz,
Bruna Mara Seco, Mayne de Oliveira
Pereira, Darlan Augusto da Costa
Rocha, Thomas Jové, Antonio Carlos
Nicodemo, Jorge Luiz Mello Sampaio
686 – 688
Heterologous Expression and Functional Characterization of
the Exogenously Acquired Aminoglycoside Resistance
Methyltransferases RmtD, RmtD2, and RmtG
Laís L. Corrêa, Marta A. Witek, Natalia
Zelinskaya, Renata C. Picão, Graeme L.
Conn
699 –702
Genome Analysis of Kingella kingae Strain KWG1 Reveals How
a
-Lactamase Gene Inserted in the Chromosome of This
Species
Philippe Bidet, Romain Basmaci, Julien
Guglielmini, Catherine Doit, Christelle
Jost, André Birgy, Stéphane Bonacorsi
703–708
Emergence of Carbapenem-Resistant Serotype K1 Hypervirulent
Klebsiella pneumoniae Strains in China
Rong Zhang, Dachuan Lin,
Edward Wai-chi Chan, Danxia Gu,
Gong-Xiang Chen, Sheng Chen
709 –711
SUSCEPTIBILITY
Microbicides Alter the Expression and Function of RND-Type
Efflux Pump AdeABC in Biofilm-Associated Cells of
Acinetobacter baumannii Clinical Isolates
Suvarna Krishnamoorthy,
Bhavikkumar P. Shah, Hiu Ham Lee,
Luis R. Martinez
57– 63
Escherichia coli Overexpressing a Baeyer-Villiger
Monooxygenase from Acinetobacter radioresistens Becomes
Resistant to Imipenem
Daniela Minerdi, Ivan Zgrablic, Silvia
Castrignanò, Gianluca Catucci, Claudio
Medana, Maria Elena Terlizzi, Giorgio
Gribaudo, Gianfranco Gilardi, Sheila J.
Sadeghi
64 –74
In Vitro and In Vivo Antimicrobial Activities of Minocycline in
Combination with Azithromycin, Clarithromycin, or
Tigecycline against Pythium insidiosum
Francielli P. K. Jesus, Érico S. Loreto,
Laerte Ferreiro, Sydney H. Alves, David
Driemeier, Suyene O. Souza, Raqueli T.
França, Sonia T. A. Lopes, Maiara B.
Pilotto, Aline Ludwig, Maria I. Azevedo,
Tatiana C. Ribeiro, Juliana S. M.
Tondolo, Janio M. Santurio
87–91
Antimicrobial Susceptibilities of Aerobic and Facultative Gram-
Negative Bacilli from Intra-abdominal Infections in Patients
from Seven Regions in China in 2012 and 2013
Hui Zhang, Qiwen Yang, Kang Liao,
Yuxing Ni, Yunsong Yu, Bijie Hu,
Ziyong Sun, Wenxiang Huang, Yong
Wang, Anhua Wu, Xianju Feng,
Yanping Luo, Zhidong Hu, Yunzhuo
Chu, Shulan Chen, Bin Cao, Jianrong
Su, Bingdong Gui, Qiong Duan,
Shufang Zhang, Haifeng Shao, Haishen
Kong, Robert E. Badal, Yingchun Xu
245–251
In Vitro Activity of Ceftaroline against Staphylococcus aureus
Isolated in 2012 from Asia-Pacific Countries as Part of the
AWARE Surveillance Program
Douglas J. Biedenbach, Richard A. Alm,
Sushmita D. Lahiri, Edina Reiszner,
Daryl J. Hoban, Daniel F. Sahm,
Samuel K. Bouchillon, Jane E. Ambler
343–347
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
Activity of Tobramycin against Cystic Fibrosis Isolates of
Burkholderia cepacia Complex Grown as Biofilms
Sarah Kennedy, Trevor Beaudoin,
Yvonne C. W. Yau, Emma Caraher,
James E. A. Zlosnik, David P. Speert,
John J. LiPuma, Elizabeth Tullis,
Valerie Waters
348 –355
Type III Secretion-Dependent Sensitivity of Escherichia coli
O157 to Specific Ketolides
Romina J. Fernandez-Brando, Nao
Yamaguchi, Amin Tahoun, Sean P.
McAteer, Trudi Gillespie, Dai Wang,
Sally A. Argyle, Marina S. Palermo,
David L. Gally
459 – 470
Multidrug-Resistant Neisseria gonorrhoeae Isolates from
Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase
Inhibitor, ETX0914 (AZD0914)
Xiao-Hong Su, Bao-Xi Wang,
Wen-Jing Le, Yu-Rong Liu, Chuan
Wan, Sai Li, Richard A. Alm, John P.
Mueller, Peter A. Rice
621– 623
Effect of High-Dose Antimicrobials on Biofilm Growth of
Achromobacter Species Isolated from Cystic Fibrosis Patients
Sean K. Tom, Yvonne C. W. Yau,
Trevor Beaudoin, John J. LiPuma,
Valerie Waters
650 – 652
High Prevalence of Biocide Resistance Determinants in
Staphylococcus aureus Isolates from Three African Countries
Teresa Conceição, Céline Coelho,
Hermínia de Lencastre, Marta
Aires-de-Sousa
678 – 681
Azole Resistance in Aspergillus fumigatus Clinical Isolates from
an Italian Culture Collection
Cristina Lazzarini, Maria Carmela
Esposto, Anna Prigitano, Massimo
Cogliati, Gabriella De Lorenzis,
Anna Maria Tortorano
682– 685
Susceptibility of Clostridium difficile Isolates of Varying
Antimicrobial Resistance Phenotypes to SMT19969 and
11 Comparators
Jane Freeman, Jonathan Vernon,
Richard Vickers, Mark H. Wilcox
689 – 692
ANALYTICAL PROCEDURES
Bioassay for Determining Voriconazole Serum Levels in Patients
Receiving Combination Therapy with Echinocandins
Maria Siopi, Efthymios Neroutsos,
Kalliopi Zisaki, Maria Gamaletsou,
Maria Pirounaki, Panagiotis Tsirigotis,
Nikolaos Sipsas, Aristides Dokoumetzidis,
Evgenios Goussetis, Loukia Zerva, Georgia
Valsami, Joseph Meletiadis
632– 636
ANTIVIRAL AGENTS
Generation and Characterization of ALX-0171, a Potent Novel
Therapeutic Nanobody for the Treatment of Respiratory
Syncytial Virus Infection
Laurent Detalle, Thomas Stohr,
Concepción Palomo, Pedro A. Piedra,
Brian E. Gilbert, Vicente Mas, Andrena
Millar, Ultan F. Power, Catelijne
Stortelers, Koen Allosery, José A.
Melero, Erik Depla
6 –13
Drug Interactions with the Direct-Acting Antiviral Combination
of Ombitasvir and Paritaprevir-Ritonavir
Prajakta S. Badri, Sandeep Dutta,
Haoyu Wang, Thomas J. Podsadecki,
Akshanth R. Polepally, Amit Khatri,
Jiuhong Zha, Yi-Lin Chiu, Walid M.
Awni, Rajeev M. Menon
105–114
Antiretrovirals, Methamphetamine, and HIV-1 Envelope
Protein gp120 Compromise Neuronal Energy Homeostasis in
Association with Various Degrees of Synaptic and Neuritic
Damage
Ana B. Sanchez, Giuseppe P. Varano,
Cyrus M. de Rozieres, Ricky Maung,
Irene C. Catalan, Cari C. Dowling,
Natalia E. Sejbuk, Melanie M. Hoefer,
Marcus Kaul
168 –179
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
Alkyl Amine Bevirimat Derivatives Are Potent and Broadly
Active HIV-1 Maturation Inhibitors
Emiko Urano, Sherimay D. Ablan,
Rebecca Mandt, Gary T. Pauly, Dina M.
Sigano, Joel P. Schneider, David E.
Martin, Theodore J. Nitz, Carl T. Wild,
Eric O. Freed
190 –197
Modification of the Host Cell Lipid Metabolism Induced by
Hypolipidemic Drugs Targeting the Acetyl Coenzyme A
Carboxylase Impairs West Nile Virus Replication
Teresa Merino-Ramos, Ángela
Vázquez-Calvo, Josefina Casas,
Francisco Sobrino, Juan-Carlos Saiz,
Miguel A. Martín-Acebes
307–315
Intracellular Activation of Tenofovir Alafenamide and the Effect
of Viral and Host Protease Inhibitors
Gabriel Birkus, Rujuta A. Bam,
Madeleine Willkom, Christian R. Frey,
Luong Tsai, Kirsten M. Stray, Stephen R.
Yant, Tomas Cihlar
316 –322
No Need for Lopinavir Dose Adjustment during Pregnancy: a
Population Pharmacokinetic and Exposure-Response Analysis
in Pregnant and Nonpregnant HIV-Infected Subjects
Ahmed Hamed Salem, Aksana Kaefer
Jones, Marilia Santini-Oliveira,
Graham P. Taylor, Kristine B.
Patterson, Angela M. Nilius,
Cheri Enders Klein
400 – 408
Incompatible Natures of the HIV-1 Envelope in Resistance to
the CCR5 Antagonist Cenicriviroc and to Neutralizing
Antibodies
Takeo Kuwata, Ikumi Enomoto,
Masanori Baba, Shuzo Matsushita
437– 450
Insights into the Molecular Mechanism of Polymerization and
Nucleoside Reverse Transcriptase Inhibitor Incorporation by
Human PrimPol
Andrea C. Mislak, Karen S. Anderson
561–569
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor
Targeting Dengue Virus RNA-Dependent RNA Polymerase
Hong-Tao Xu, Susan P. Colby-
Germinario, Said Hassounah, Peter K.
Quashie, Yingshan Han, Maureen
Oliveira, Brent R. Stranix, Mark A.
Wainberg
600 – 608
C5A Protects Macaques from Vaginal Simian-Human
Immunodeficiency Virus Challenge
Ronald S. Veazey, Udayan Chatterji,
Michael Bobardt, Kasi E. Russell-Lodrigue,
Jian Li, Xiaolei Wang, Philippe A. Gallay
693– 698
EPIDEMIOLOGY AND SURVEILLANCE
Antibiotic Resistance among Clinical Ureaplasma Isolates
Recovered from Neonates in England and Wales between 2007
and 2013
Michael L. Beeton, Victoria J. Chalker,
Lucy C. Jones, Nicola C. Maxwell,
O. Brad Spiller
52–56
Risk Factors and Outcomes for Bloodstream Infections
Secondary to Clostridium difficile Infection
Marco Falcone, Alessandro Russo,
Federica Iraci, Paolo Carfagna, Paola
Goldoni, Vincenzo Vullo, Mario
Venditti
252–257
A Two-Year Surveillance in Five Colombian Tertiary Care
Hospitals Reveals High Frequency of Non-CG258 Clones of
Carbapenem-Resistant Klebsiella pneumoniae with Distinct
Clinical Characteristics
Ana M. Ocampo, Liang Chen, Astrid V.
Cienfuegos, Gustavo Roncancio,
Kalyan D. Chavda, Barry N. Kreiswirth,
J. Natalia Jiménez
332–342
Quantitative Analysis of Single-Nucleotide Polymorphism for
Rapid Detection of TR
34
/L98H- and TR
46
/Y121F/T289A-Positive
Aspergillus fumigatus Isolates Obtained from Patients in Iran
from 2010 to 2014
Faezeh Mohammadi, Seyed Jamal
Hashemi, Jan Zoll, Willem J. G.
Melchers, Haleh Rafati, Parvin
Dehghan, Sasan Rezaie, Ali Tolooe,
Yalda Tamadon, Henrich A. van der
Lee, Paul E. Verweij, Seyedmojtaba
Seyedmousavi
387–392
Fluoroquinolone and Macrolide Exposure Predict Clostridium
difficile Infection with the Highly Fluoroquinolone- and
Macrolide-Resistant Epidemic C. difficile Strain BI/NAP1/027
Jeffrey T. Wieczorkiewicz, Bert K.
Lopansri, Adam Cheknis, James R.
Osmolski, David W. Hecht, Dale N.
Gerding, Stuart Johnson
418 – 423
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
Emergence of Mutations in the K13 Propeller Gene of
Plasmodium falciparum Isolates from Dakar, Senegal, in
2013-2014
Agathe Boussaroque, Bécaye Fall,
Marylin Madamet, Cheikhou Camara,
Nicolas Benoit, Mansour Fall, Aminata
Nakoulima, Pierre Dionne, Kadidiatou Ba
Fall, Bakary Diatta, Yaya Diémé,
Boubacar Wade, Bruno Pradines
624 – 627
EXPERIMENTAL THERAPEUTICS
Biofilms of Pathogenic Nontuberculous Mycobacteria Targeted
by New Therapeutic Approaches
Thet Tun Aung, Joey Kuok Hoong
Yam, Shuimu Lin, Shuhaida Mohamed
Salleh, Michael Givskov, Shouping Liu,
Nyein Chan Lwin, Liang Yang,
Roger W. Beuerman
24 –35
Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial
Activity and Inhibit Indoleamine Dioxygenase
Esther Jortzik, Kathleen Zocher, Antje
Isernhagen, Boniface M. Mailu, Stefan
Rahlfs, Giampietro Viola, Sergio
Wittlin, Nicholas H. Hunt, Heiko
Ihmels, Katja Becker
115–125
Molecule Targeting Glucosyltransferase Inhibits Streptococcus
mutans Biofilm Formation and Virulence
Zhi Ren, Tao Cui, Jumei Zeng, Lulu
Chen, Wenling Zhang, Xin Xu, Lei
Cheng, Mingyun Li, Jiyao Li, Xuedong
Zhou, Yuqing Li
126 –135
In Vitro Pharmacodynamics of Human Simulated Exposures of
Telavancin against Methicillin-Susceptible and -Resistant
Staphylococcus aureus with and without Prior Vancomycin
Exposure
Abrar K. Thabit, David P. Nicolau,
Joseph L. Kuti
222–228
Contribution of Oxazolidinones to the Efficacy of Novel
Regimens Containing Bedaquiline and Pretomanid in a Mouse
Model of Tuberculosis
Rokeya Tasneen, Fabrice Betoudji,
Sandeep Tyagi, Si-Yang Li, Kathy
Williams, Paul J. Converse, Véronique
Dartois, Tian Yang, Carl M. Mendel,
Khisimuzi E. Mdluli, Eric L.
Nuermberger
270 –277
In Vivo Synergy of Amphotericin B plus Posaconazole in
Murine Aspergillosis
Adela Martin-Vicente, Javier Capilla,
Josep Guarro
296 –300
Cefotaxime and Amoxicillin-Clavulanate Synergism against
Extended-Spectrum-
-Lactamase-Producing Escherichia coli in
a Murine Model of Urinary Tract Infection
B. Rossi, J. F. Soubirou, F. Chau, L.
Massias, S. Dion, R. Lepeule, B. Fantin,
A. Lefort
424 – 430
Fosfomycin plus
-Lactams as Synergistic Bactericidal
Combinations for Experimental Endocarditis Due to
Methicillin-Resistant and Glycopeptide-Intermediate
Staphylococcus aureus
A. del Río, C. García-de-la-Mària, J. M.
Entenza, O. Gasch, Y. Armero, D. Soy,
C. A. Mestres, J. M. Pericás, C. Falces,
S. Ninot, M. Almela, C. Cervera, J. M.
Gatell, A. Moreno, P. Moreillon, F.
Marco, J. M. Miró, the Hospital Clinic
Experimental Endocarditis Study
Group
478 – 486
Antimicrobial Peptide CMA3 Derived from the CA-MA Hybrid
Peptide: Antibacterial and Anti-inflammatory Activities with
Low Cytotoxicity and Mechanism of Action in Escherichia coli
Jong-kook Lee, Chang Ho Seo, Tudor
Luchian, Yoonkyung Park
495–506
In Vitro Activity of ASP2397 against Aspergillus Isolates with or
without Acquired Azole Resistance Mechanisms
Maiken Cavling Arendrup,
Rasmus Hare Jensen, Manuel
Cuenca-Estrella
532–536
Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In
Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate
with Sensitivity of Cryptosporidium parvum Growth in Cell
Culture
Theresa B. Kuhlenschmidt, Florentine U.
Rutaganira, Shaojun Long, Keliang
Tang, Kevan M. Shokat, Mark S.
Kuhlenschmidt, L. David Sibley
570 –579
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
Characterization of the Antimicrobial Peptide Penisin, a Class Ia
Novel Lantibiotic from Paenibacillus sp. Strain A3
Piyush Baindara, Vasvi Chaudhry,
Garima Mittal, Luciano M. Liao,
Carolina O. Matos, Neeraj Khatri,
Octavio L. Franco, Prabhu B. Patil,
Suresh Korpole
580 –591
Development of an Intracellular Screen for New Compounds
Able To Inhibit Mycobacterium tuberculosis Growth in Human
Macrophages
Flavia Sorrentino, Ruben
Gonzalez del Rio, Xingji Zheng, Jesus
Presa Matilla, Pedro Torres Gomez,
Maria Martinez Hoyos, Maria Esther
Perez Herran, Alfonso Mendoza
Losana, Yossef Av-Gay
640 – 645
Efficacy of Extended-Interval Dosing of Micafungin Evaluated
Using a Pharmacokinetic/Pharmacodynamic Study with
Humanized Doses in Mice
A. Lepak, K. Marchillo, J. VanHecker,
N. Azie, D. Andes
674 – 677
CLINICAL THERAPEUTICS
Large Cohort Study of Central Venous Catheter Thrombosis
during Intravenous Antibiotic Therapy
Stéphanie Guillet, Valérie Zeller,
Vincent Dubée, Françoise Ducroquet,
Nicole Desplaces, Marie Hélène
Horellou, Simon Marmor, Jean Marc
Ziza
36 – 43
Serum Levels of Antituberculosis Drugs and Their Effect on
Tuberculosis Treatment Outcome
Jong Sun Park, Jae-Yeon Lee, Yeon Joo
Lee, Se Joong Kim, Young-Jae Cho,
Ho Il Yoon, Choon-Taek Lee, Junghan
Song, Jae Ho Lee
92–98
Nonimpact of Decolonization as an Adjunctive Measure to
Contact Precautions for the Control of Methicillin-Resistant
Staphylococcus aureus Transmission in Acute Care
Lance R. Peterson, Marc O. Wright,
Jennifer L. Beaumont, Vanida
Komutanon, Parul A. Patel, Donna M.
Schora, Bryan H. Schmitt, Ari Robicsek
99 –104
Population Pharmacokinetics of Doripenem in Critically Ill
Patients with Sepsis in a Malaysian Intensive Care Unit
Mohd H. Abdul-Aziz, Azrin N. Abd
Rahman, Mohd-Basri Mat-Nor, Helmi
Sulaiman, Steven C. Wallis, Jeffrey
Lipman, Jason A. Roberts, Christine E.
Staatz
206 –214
Case-Control Study of Telavancin as an Alternative Treatment
for Gram-Positive Bloodstream Infections in Patients with
Cancer
Anne-Marie Chaftari, Ray Hachem,
Mary Jordan, Kumait Garoge, Zainab
Al Hamal, Aline El Zakhem, George M.
Viola, Bruno Granwehr, Victor
Mulanovich, Andrew Gagel, Ruth
Reitzel, Ammar Yousif, Ying Jiang,
Issam Raad
239 –244
Neutropenia Associated with Long-Term Ceftaroline Use
Katherine W. LaVie, Scott W.
Anderson, Hollis R. O’Neal, Jr.,
Todd W. Rice, Tatiana C. Saavedra,
Catherine S. O’Neal
264 –269
Treatment Outcomes with Fluoroquinolone-Containing
Regimens for Isoniazid-Resistant Pulmonary Tuberculosis
Hyun Lee, Byeong-Ho Jeong, Hye Yun
Park, Kyeongman Jeon, Hee Jae Huh,
Nam Yong Lee, Won-Jung Koh
471– 477
An Amphipathic Undecapeptide with All
D
-Amino Acids Shows
Promising Activity against Colistin-Resistant Strains of
Acinetobacter baumannii and a Dual Mode of Action
Alberto Oddo, Thomas T. Thomsen,
Susanne Kjelstrup, Ciara Gorey, Henrik
Franzyk, Niels Frimodt-Møller, Anders
Løbner-Olesen, Paul R. Hansen
592–599
The Clinically Tested Gardos Channel Inhibitor Senicapoc
Exhibits Antimalarial Activity
Venée N. Tubman, Pedro Mejia,
Boris E. Shmukler, Amy K. Bei, Seth L.
Alper, James R. Mitchell, Carlo
Brugnara, Manoj T. Duraisingh
613– 616
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
In Vitro Activity of Ceftolozane-Tazobactam against Anaerobic
Organisms Identified during the ASPECT-cIAI Study
Eliana S. Armstrong, David J. Farrell,
Melissa Palchak, Judith N. Steenbergen
666 – 668
Ertapenem-Containing Double-Carbapenem Therapy for
Treatment of Infections Caused by Carbapenem-Resistant
Klebsiella pneumoniae
Jessica B. Cprek, Jason C. Gallagher
669 – 673
PHARMACOLOGY
Validation and Application of a Dried Blood Spot Ceftriaxone
Assay
Madhu Page-Sharp, Troy Nunn, Sam
Salman, Brioni R. Moore, Kevin T.
Batty, Timothy M. E. Davis, Laurens
Manning
14 –23
Pharmacokinetics/Pharmacodynamics of Peptide Deformylase
Inhibitor GSK1322322 against Streptococcus pneumoniae,
Haemophilus influenzae, and Staphylococcus aureus in Rodent
Models of Infection
Jennifer Hoover, Thomas
Lewandowski, Robert J. Straub,
Steven J. Novick, Peter DeMarsh, Kelly
Aubart, Stephen Rittenhouse,
Magdalena Zalacain
180 –189
Pharmacokinetic-Pharmacodynamic Model for the Effect of
L
-Arginine on Endothelial Function in Patients with Moderately
Severe Falciparum Malaria
Janneke M. Brussee, Tsin W. Yeo,
Daniel A. Lampah, Nicholas M. Anstey,
Stephen B. Duffull
198 –205
Pharmacodynamics of Isavuconazole in a Dynamic In Vitro
Model of Invasive Pulmonary Aspergillosis
Helen Box, Joanne Livermore, Adam
Johnson, Laura McEntee, Timothy W.
Felton, Sarah Whalley, Joanne
Goodwin, William W. Hope
278 –287
Pharmacodynamics of Ceftazidime and Avibactam in
Neutropenic Mice with Thigh or Lung Infection
Johanna Berkhout, Maria J. Melchers,
Anita C. van Mil, Seyedmojtaba
Seyedmousavi, Claudia M. Lagarde,
Virna J. Schuck, Wright W. Nichols,
Johan W. Mouton
368 –375
Network Meta-analysis and Pharmacoeconomic Evaluation of
Fluconazole, Itraconazole, Posaconazole, and Voriconazole in
Invasive Fungal Infection Prophylaxis
Ying Jiao Zhao, Ai Leng Khoo, Gloria
Tan, Monica Teng, Caroline Tee,
Ban Hock Tan, Benjamin Ong,
Boon Peng Lim, Louis Yi Ann Chai
376 –386
Influence of Colistin Dose on Global Cure in Patients with
Bacteremia Due to Carbapenem-Resistant Gram-Negative
Bacilli
Gabrielle A. Gibson, Seth R. Bauer,
Elizabeth A. Neuner, Stephanie N. Bass,
Simon W. Lam
431– 436
Model-Based Evaluation of Higher Doses of Rifampin Using a
Semimechanistic Model Incorporating Autoinduction and
Saturation of Hepatic Extraction
Maxwell T. Chirehwa, Roxana
Rustomjee, Thuli Mthiyane, Philip
Onyebujoh, Peter Smith, Helen
McIlleron, Paolo Denti
487– 494
Pharmacodynamics of Ceftolozane plus Tazobactam Studied in
an In Vitro Pharmacokinetic Model of Infection
Alasdair P. MacGowan, Alan R. Noel,
Sharon G. Tomaselli, Donna Nicholls,
Karen E. Bowker
515–521
Population Pharmacokinetics and Pharmacodynamics of
Extended-Infusion Piperacillin and Tazobactam in Critically Ill
Children
Kristen Nichols, Eun Kyoung Chung,
Chad A. Knoderer, Lauren E. Buenger,
Daniel P. Healy, Jennifer Dees,
Ashley S. Crumby, Michael B. Kays
522–531
Effect of SLCO1B1 Polymorphisms on Rifabutin
Pharmacokinetics in African HIV-Infected Patients with
Tuberculosis
Stefanie Hennig, Suhashni Naiker,
Tarylee Reddy, Deirdre Egan, Tracy
Kellerman, Lubbe Wiesner, Andrew
Owen, Helen McIlleron, Alexander
Pym
617– 620
Cadazolid Does Not Promote Intestinal Colonization of
Vancomycin-Resistant Enterococci in Mice
Peter Seiler, Michel Enderlin-Paput,
Philippe Pfaff, Maria Weiss, Daniel
Ritz, Martine Clozel, Hans H. Locher
628 – 631
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Continued on following page
LETTER TO THE EDITOR
Effect of Meropenem Concentration on the Detection of Low
Numbers of Carbapenem-Resistant Enterobacteriaceae
Windy D. Tanner, Robyn M. Atkinson,
Ramesh K. Goel, Christina A.
Porucznik, Lowell Scott Benson,
James A. VanDerslice
712–713
ERRATA
Erratum for Bueno et al., Coproduction of 16S rRNA
Methyltransferase RmtD or RmtG with KPC-2 and CTX-M
Group Extended-Spectrum
-Lactamases in Klebsiella
pneumoniae
Maria Fernanda C. Bueno, Gabriela R.
Francisco, Jessica A. O’Hara,
Doroti de Oliveira Garcia, Yohei Doi
714
Erratum for Antonov et al., “Erratum for Antonov et al., High
Prevalence of Pupirocin Resistance in Staphylococcus aureus
Isolates from a Pediatric Population”
Nina K. Antonov, Maria C. Garzon,
Kimberly D. Morel, Susan Whittier,
Paul J. Planet, Christine T. Lauren
715
JANUARY 2016 • VOLUME 60 • NUMBER 1
Continued from preceding page
Dostları ilə paylaş: |