Common Names: aloe Latin Names: Aloe vera, Aloe africana, Aloe arborescens, Aloe barbadensis Background

What Do We Know About Safety?

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  Topical use of aloe gel is generally well tolerated. However, there have been occasional reports of burning, itching, and eczema with topical use of aloe gel. Oral use of aloe latex can cause abdominal pain and cramps. Oral consumption of aloe leaf extracts (for as little as 3 weeks and as long as 5 years) has been related to cases of acute hepatitis.
  
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  Animal studies have noted an association between aloe vera leaf extract taken orally and gastrointestinal cancer in rats and mice; however, concerns were expressed about the differences in the product used in that study and those commonly used by consumers. Thus, more research is needed to assess the relevance to human health.
  
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  Overuse of aloe latex may increase the risk of adverse effects from the drug digoxin, used for some heart problems.
  
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  Aloe—both in gel and latex form—when taken by mouth may be unsafe during pregnancy and while breastfeeding.
  

Keep in Mind

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  Take charge of your health—talk with your health care providers about any complementary health approaches you use. Together, you can make shared, well-informed decisions.
  

For More Information

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  Using Dietary Supplements Wisely
  
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  Know the Science: How Medications and Supplements Can Interact
  
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  Know the Science: 9 Questions To Help You Make Sense of Health Research
  

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