Debridement



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defining Stalled wounds

Stalled wounds are generally considered those that do not heal at least 15% in two weeks.  For example:

n

  Pressure ulcers that do not progress at least 39% in two weeks may not heal in a timely fashion



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n

  Venous leg ulcers that do not heal at least 30% in two weeks will probably not heal in six months



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n

   Diabetic ulcers that do not heal 30% in two weeks have only a 9% chance of healing in three months



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goal 

Prepare the wound bed and promote moist wound healing.

Tissue management

T

Moisture balance



M

Epithelial  

(edge) advancement

E

I



Infection and  

inflammation control



time Management

Proper wound bed preparation is essential to promoting the wound healing process.  Utilizing the Time 

Management protocol will help to keep that wound on track.



Autolytic debridement

 

uses the body’s own enzymes 



and moisture to re-hydrate, soften and finally liquefy eschar 

and slough.  During autolysis, enzymes present in the wound 

have the effect of liquefying non-viable tissue.  Clinicians foster 

autolytic debridement by utilizing moist wound dressings.  By 

maintaining a moist wound environment, the body is able to 

use its own processes to eliminate necrotic tissue.  Autolytic 

debridement can be achieved with the use of occlusive or  

semi-occlusive dressings which maintain wound fluid in contact 

with the necrotic tissue. It is virtually painless for the patient and 

safe, yet is generally  slower than other forms of debridement. 

It can be used on its own, after surgical debridement, or in 

conjunction with enzymatic or mechanical debridement. 

Mechanical debridement

 is a process in which force is 

exerted on the necrotic tissue to rip, pull, push or abrade away 

the devitalized tissue from the healthy tissue.  Mechanical 

debridement is often non-selective and may remove or cause 

damage to healthy tissue as well as necrotic tissue.  Examples 

of mechanical debridement include wet-to-dry dressings, wound 

irrigation, pulsitile lavage, whirlpool, contact ultrasound and 

scrubbing the surface with gauze.  Wet-to-dry dressings do not 

provide a moist wound healing environment and are not optimal 

for wound care once the wound is free of necrotic tissue. 

Sharp debridement

 is the removal of devitalized tissue by 

a skilled clinician, typically using a scalpel, scissors, curette 

or other sharp instrument.  Clinicians use conservative sharp 

debridement to remove loosely adherent nonviable tissue at 

the bedside or in a clinical setting.  Surgical debridement is 

done by a physician usually in the operating room, under 

anesthesia, with instruments and/or a laser when the tissue 

removal needs are extensive, or when the patient has a 

serious infection associated with the wound.  Although 

sharp debridement is fast, it is non-selective and can be 

very painful to the patient. 

Enzymatic debridement,

 or chemical debridement, 

makes use of certain enzymes and other compounds to 

dissolve necrotic tissue.  It requires a prolonged period 

of enzyme activity, and a moist wound environment with 

appropriate pH and temperature.  Enzymes are inactivated 

by metals in some wound care products (silver, zinc).

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The enzyme used in the U.S., collagenase, digests collagen 



in necrotic tissue by dissolving the collagen “anchors” that 

secure the avascular tissue to the wound bed.  Collagenase 

has been shown to be most active within a pH range of 6 

to 8.


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Biologic debridement



 uses maggots grown from the 

sterilized eggs of Lucilia sericata.  The larvae are placed 

in the wound bed, where it is theorized that they secrete 

proteolytic enzymes that break down necrotic tissue, which 

they then ingest.  This is considered an option when the 

patient is not a surgical candidate and has not responded 

to other methods of debridement.

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Types of Debridement



2,4,5

The standard methods of debridement are autolytic, mechanical, enzymatic, sharp and biologic.  The method 

of debridement used, often depends on the amount of necrotic tissue present in the wound bed, the extent of 

the wound, and the patient’s medical history and overall condition.  Clinicians sometimes use more than one 

debridement method in conjunction in order to achieve the most successful removal of necrotic tissue.

Continual vs. intermittent debridement

It has been found that rates of healing increase when wounds are debrided more frequently.

4

  With the increased 



knowledge of biofilms and their ability to repopulate, as well as the damaging effects of elevated proteases (MMP’s) 

of the chronic wound, more focus has been placed on continual debridement vs. single or intermittent debridement. 

Continual debridement provides a consistent action of removing necrotic tissue from the wound bed over a period of time, 

unlike single or intermittent methods.  The ability to provide continual and consistent removal of necrotic tissue helps to 

create an optimal environment for healing and allows for less disruption to the wound bed.



The Role of

 

MEDIHONEY



®

The overall goal for wound bed preparation is to remove factors that delay healing.

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  These factors in a 



stalled or chronic wound include necrotic tissue and altered levels and composition of wound exudates. 

MEDIHONEY

®

 dressings, containing Active Leptospermum Honey (ALH), address factors that cause 



delayed healing in chronic wounds.  As demonstrated in multiple RCTs and 100s of clinical papers, 

ALH helps to jump start wounds and promote autolytic debridement due to its multiple mechanisms of 

action.  MEDIHONEY

®

’s osmotic effect addresses multiple aspects of debridement quickly for optimal 



patient care.  The high sugar content of MEDIHONEY

®

 aids in the increased flow of fluid to support the 



continual cleansing of the wound environment, helping to remove devitalized or necrotic tissue through 

an osmotic effect.

21, 22

  Additionally, the low pH of MEDIHONEY



®

 helps to lower the pH levels within 

the wound environment,

9,27


 which has been shown to have wound healing benefits.

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5




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