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Significance
While many of the ideas of calculus had been developed earlier in Greece, China, India, Iraq, Persia, and Japan, the use of calculus began in Europe, during the 17th century, when Isaac Newton and Gottfried Wilhelm Leibniz built on the work of earlier mathematicians to introduce its basic principles. The development of calculus was built on earlier concepts of instantaneous motion and area underneath curves.
Applications of differential calculus include computations involving velocity and acceleration, the slope of a curve, and optimization. Applications of integral calculus include computations involving area, volume, arc length, center of mass, work, and pressure. More advanced applications include power series and Fourier series.
Calculus is also used to gain a more precise understanding of the nature of space, time, and motion. For centuries, mathematicians and philosophers wrestled with paradoxes involving division by zero or sums of infinitely many numbers. These questions arise in the study of motion and area. The ancient Greek philosopher Zeno of Elea gave several famous examples of such paradoxes. Calculus provides tools, especially the limit and the infinite series, that resolve the paradoxes.