General microbiology

E. Binding of mast cell-fixed IgE
32. A 27- year-old woman has dropped penicillin containing eye drops. In few minutes there appeared feeling of itching, burning of the skin, lips and eyelids edema, whistling cough, decreasing of BP. What antibodies take part in the development of this allergic reaction?
A. IgA and IgM B. IgM and IgG C. IgM and IgD
D. IgG and IgD E. IgE and IgG
33. Skin samples of a patient with bronchial asthma revealed allergen sensitization of poplar fuzz. What factor of immune system plays the main part in development of this immunopathological state?
A. IgE B. IgD C. IgM
D. Sensitized Т-lymphocytes E. –
34. A youth, aged 15, from childhood suffers from atopic dermatitis and allergy to the shellfish. In the last 3 months after acquiring aquarium fish, rhinitis, conjunctivitis, itching in the nose developed. What level of immunologic index should be defined in this case?
A. IgE B. IgG C. IgM
D. IgA E. Circulating immunocomplexes
35. A 7-year-old child complains of itching, papular erythematous rash, dry skin. Objectively: there is lichenification in the popliteal fossae and antecubital spaces. What immunologic indicator if found in the blood serum will verify the diagnosis (atopic dermatitis)?
A. Total IgE B. Secretory IgA
C. IgM D. IgG E. IgD
36. What condition may develop 15-30 minutes after re-administration of the antigen as a result of the increased level of antibodies, mainly IgE, that are adsorbed on the surface of target cells, namely tissue basophils (mast cells) and blood basophils?
A. Anaphylaxis B. Antibody-dependent cytotoxicity
C. Delayed-type hypersensitivity
D. Immune complex hyperresponsiveness E. Serum sickness
37. A 22-year-old woman ate some seafood. 5 hours later the trunk and the distal parts of limbs got covered with small itchy papules which were partially fused together. After one day, the rash disappeared spontaneously. Specify the hypersensitivity mechanism underlying these changes:
A. Atopy (local anaphylaxis) B. Systemic anaphylaxis
C. Cellular cytotoxicity D. Immune complex hypersensitivity
E. Antibody-dependent cell-mediated cytolysis
38. A 30-year-old patient has dyspnea fits, mostly at night. He has been diagnosed with bronchial asthma. What type of allergic reaction according to the Gell-Coombs classification is most likely in this case?
A. Anaphylactic B. Cytotoxic C. Stimulating
D. Immune complex E. Delayed-type hypersensitivity
39. During surgical manipulations a patient has been given novocaine injection for anesthesia. 10 minutes later the patient developed paleness, dyspnea, hypotension. What type of allergic reaction is it?
A. Anaphylactic immune reaction B. Cellulotoxic immune reaction
C. Aggregate immune reaction D. Stimulating immune reaction
E. Cell-mediated immune reaction
40. A 50 year old man who was referred to the hospital for treatment of cervical lymphadenitis underwent test for individual sensitivity to penicillin. 30 seconds after he went hot all over, AP dropped down to 0 mm Hg that led to cardiac arrest. What type of hypersensitivity reaction is it?
A. Anaphylactic B. Delayed-type hypersensitivity
C. Complement-mediated cytotoxic
D. Immunocomplex-mediated E. –
41. A 50-year-old patient has been referred for treatment of neck lymphadenitis. His individual penicillin sensitivity was tested. In 30 seconds fullbody fever raised in the patient and his arterial blood pressure dropped to 0mm Hg followed by cardiac arrest. Resuscitation was unsuccessful. Autopsy revealed acute venous hyperemia of viscera. Histological study revealed mastcells (tissue basocytes) degranulation in the skin (at the area of injections), myocardium and lungs. What kind of hypersensitivity reaction occurred in the patient?