Guideline Development Group


Table 2: Level Of Evidence



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Table 2: Level Of Evidence


Level

Criteria

I

Evidence obtained from high-quality diagnostic studies, prognostic or prospective studies, cohort studies or randomized controlled trials, meta-analyses or systematic reviews (critical appraisal score > 50% of criteria)

II

Evidence obtained from lesser-quality diagnostic studies, prognostic or prospective studies, cohort studies or randomized controlled trials, meta-analyses or systematic reviews (eg, weaker diagnostic criteria and reference standards, improper randomization, no blinding, <80% follow-up)

(critical appraisal score <50% of criteria)



III

Case-controlled studies or retrospective studies

IV

Case studies and case series

V

Expert opinion



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