J O U R N A L O F WO U N D C A R E Vo l 2 2 . N o 1 . E W M A D o c u M E N t 2 0 1 3
beads measuring 0.1–0.3mm in diameter, or as
a paste with polyethylene glycol. The product
consists of unbranched dextran-polymer chains
which are interconnected by gycerol bridges into a
three-dimensional network.
Indication
Absorptive dressings are recommended for the
treatment of exudative wounds (low, medium or
high), with yellow sloughy surfaces.
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Mechanismofaction
Absorptive dressings are highly hydrophilic and
rapidly absorb exudate from the necrotic, sloughy
mass. One gramme of dextranomer can absorb up
to 4g of fluid. Prostaglandins, hormones and other
small molecules enter the matrix of the absorptive
dressings, while larger particles, such as bacteria
and wound debris, become concentrated at the
surface of the dressing layer. When the dressings are
changed, or the beads are washed out, the absorbed
and trapped necrotic material is removed.
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Administration
Dextranomer should be applied in a thickness of a
least 3mm on to wounds that have previously been
cleaned with solutions. When the wound is dressed,
there must be some room for expansion, as the
dressing absorbs a lot of fluid. The absorbent dressing
should be replaced after 1–3 days, depending on the
extent of exudation. When it assumes a grey–yellow
colour, it is saturated and should be removed.
Benefits
Absorptive dressings are easy-to-handle products
that can be used even with highly exudative
wounds and thus support the exudate management.
Contraindications
As with absorptive dressings with autolytic
properties, absorptive dressings should not be
used near the eyes, in deep wounds with narrow
openings, or wounds in body cavities. Other
contraindications are known contact sensitisation
to ingredients of the dressings.
Sideeffects
Beside some reports of erythema, slightly blistered
skin or dehydration of the wound bed,
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the most
important adverse effect is pain on removal of the
saturated dressing from the wounds. This effect is
the result of the adherence effects.
Honey
Background
The first records of the use of honey in
wound management are already more than
4000 years old.
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Honey can be characterised
as a combination products but is, as a purely
natural substance, placed in a separate chapter.
It is a viscous, supersaturated, sugar solution,
containing approximately 30% glucose, 40%
fructose, 5% sucrose and 20% water, as well as
many other substances, such as amino acids,
vitamins, minerals and enzymes. As well as honey
preparations in tubes for wound treatments,
dressing pads pre-impregnated with honey are
also commercially available.
Indications
Honey has been used to treat a wide range of
wound types with necrotic tissue or slough. Other
indications are wound infections, even when they
are caused by, for example, Pseudomonas aeruginosa
or meticillin-resistant Staphylococcus aureus (MRSA).
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Action
Honey osmotically draws fluid from the
surrounding tissue. This reduce wound oedema
and, along with the increased exudate, results in
autolytic debridement. The claimed antimicrobial
effectiveness of honey may be partly explained by
an osmotic dehydration, a low pH-value of 3.0–4.5
and the release of small amounts of hydrogen
peroxide or methylglyoxal.
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Since honey is a
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