Lstm, Ronald Ross and malaria

LSTM, Ronald Ross 

and malaria 

A brief history

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Ronald Ross’ career

 

1857:

 Ronald Ross is born in Almora (present 

day Uttarakhand), India

1894:

 Sir Patrick Manson, the ‘founding father’ 

of Tropical Medicine, introduces the surgeon 

Ronald Ross to malaria research

1897:

 Ronald Ross discovers the malaria 

parasite inside the Anopheles mosquito during 

his work for the Indian Medical Service

1898:

 Ross demonstrates the transmission 

of the malarial parasite from infected to non-

infected birds via Culex mosquitoes

1899:

 LSTM appoints Ronald Ross as its first 

lecturer

1902:

 Ross wins the Nobel Prize for Medicine 

for his work on malaria, becoming the first 

British Nobel laureate

1903:

 Professor of Tropical Medicine at LSTM

1912:

 Physician for Tropical Diseases at King’s 

College Hospital in London

1917:

 Honorary Consultant in Malariology in 

British War Office.

1918:

 Consultant in Malaria in the Ministry of 

Pensions and National Insurance

1926:

 Director of the Ross Institute and 

Hospital for Tropical Diseases in London

1932:

 Ross dies in London

1898:

 LSTM is founded, following a donation 

of £350 by shipping magnate Sir Alfred Jones.

1899:

 First scientific expedition to Sierra Leone 

where Ross and others study malaria

1905:

 Ross multiple expeditions overseas lead 

to recommended use of bednets to reduce 

malaria transmission

1922:

 J.W.W. Stephens discovers the 

Plasmodium ovale, a species of parasitic 

protozoa that causes tertian malaria in humans

1926:

 Lecturer, entomologist and explorer 

Dr Alwen Evans publishes ‘Breeding places 

of Anopheline mosquitoes in and around 

Freetown, Sierra Leone’

1939:

 New insectaries with temperature 

and humidity controls are being installed for 

transmission experiments

1941:

 Warrington Yorke demonstrates 

acquired resistance in a malaria parasite to an 

antimalarial drug

1942:

 Researchers develop the anti-malarial 

drug Paludrine with Imperial Chemical Industries

1945:

 Professor (and later Dean) Maegraith 

starts work on the pathogenesis of malaria

1949:

 LSTM’s Adams & Lourie report 

plasmodium vivax and plasmodium falciparum 

resistance to Paludrine

1958:

 Researchers begin studies to identify 

malaria toxins

1966:

 Professor Peters’ research leads to 

the use of drug combinations to control the 

emergence of drug resistance in malaria

1970:

 Carol Homewood publishes her work on 

the mechanism of chloroquine resistance

1986:

 Studies start on the pathology of 

cerebral malaria and early clinical studies on 

artemisinin

1999:

 First newly registered antimalarial, 

chlorproguanil/dapsone (sold commercially as 

Lapdap), to be delivered through a Product 

Development Partnership (PDP)

2005:

 LSTM sets up IVCC, a product 

development partnership (PDP) to develop new 

insecticides for public health vector control

2014:

 Researchers unlock the secret of 

multiple insecticide resistance in mosquitoes

2015:

 R. Heyderman and M.E. Molyneux 

co-author study linking cerebral malaria deaths 

to brain swelling in children

LSTM & its malaria research

 

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Vision:

To save lives in resource poor countries through research, 

education and capacity strengthening

Mission:

To reduce the burden of sickness and mortality in disease endemic countries 

through the delivery of effective interventions which improve human health and are 

relevant to the poorest communities

Values:

•  Making a difference to health and wellbeing

•  Excellence in innovation, leadership and science

•  Achieving and delivering through partnership

•  An ethical ethos founded on respect, accountability and honesty

•  Creating a great place to work and study

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