Name of journal: World Journal of Transplantation esps manuscript no: 18452 Manuscript Type: Original Article Retrospective Study



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Background

Contemporary healthcare have greatly improved the survival rates in spinal cord injuries (SCI) cases as well as their life expectancy, leading to the overall growth of the national economic burden. However, current healthcare advances have not led to any breakthrough in restoration of the functions of spinal cord after the injury, and ever since the Edwin Smith Papyrus the SCI has been classified as the ailment not to be treated. To date SCI is a verdict that entails impossibility to return to previous way of life, to restore previous working capacity and reproductive functions, resulting in tremendous social and economic losses. Inefficiency of the available SCI therapies used to be explained by the absence of the regeneration potential in adults, and the restoration of the damaged neural cells has been demonstrated only recently.



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