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Complications of intrathecal application of HSCS AND HPS
During 12 years of follow up we observed no life threatening complications resulting from the HSCs and HPs transplantation. The complications of HSCs and HPs administration were evaluated at three stages: stage 1 after the first transplantation; stage 2 after one year of the therapy that included 5.3 ± 0.5 administrations; stage 3 two years of regular administrations (10.1 ± 1.1). The complications were summed up in Table 4. We observed one case of cancer (femoral carcinoma) of 202 followed up cases. However, according to the conclusion of the experts of the Russian Cancer Research Centre, it was not associated with HSCs and HPs transplantation. Surprisingly, in the control group of 20 cases we registered one case of spontaneous brain cancer development (pituitary adenoma) too, for which the patient was operated on.
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