Test and treat for Helicobacter pylori (HP) in dyspepsia
QUICK REFERENCE GUIDE AUTHORS
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QUICK REFERENCE GUIDE AUTHORS Prof Cliodna McNulty, Head of Primary Care Unit and Honorary Visiting Professor, Public Health England and Cardiff University Dr Philippa Moore, Consultant Microbiologist, Gloucestershire Hospitals NHS Foundation Trust Dr Teh Li Chin, Consultant Microbiologist, North Bristol NHS Trust Dr Gerry Morrow, Clinical Editor, Clinical Knowledge Summaries Sarah Alton, Guidance Research Assistant, Public Health England QUICK REFERENCE GUIDE REVIEWERS Dr Mahableshwar Albur, Consultant Microbiologist, North Bristol NHS Trust Alice Alcock, Senior Biomedical Scientist, University Hospitals of North Staffordshire NHS Trust Prof John Atherton, Professor of Gastroenterology, University of Nottingham Elizabeth Beech, Prescribing Advisor, NHS Bath and North East Somerset Clinical Commissioning Group Dr John Cheesbrough, Consultant Microbiologist, Teaching Hospitals NHS Foundation Trust EY Cheung, Deputy Head of Medicines Management, NHS Camden Clinical Commissioning Group Dr David Clements, Consultant Physician/Gastroenterologist, Airedale NHS Foundation Trust Alison Dossetter, Senior Pharmaceutical Advisor, NHS East and North Hertfordshire Clinical Commissioning Group Dr Paul Edelstein, Director of Clinical Microbiology, Hospital of the University of Pennsylvania Prof Emad El-Omar, Professor of Gastroenterology, Aberdeen University Dr Keith George, Senior Consultant Gastroenterologist, Torbay and South Devon NHS Foundation Trust Dr Gauri Godbole, Consultant Medical Microbiologist, Public Health England Dr Andrew Goddard, Consultant Gastroenterologist, Royal College of Physicians Dr Stephen Grainger, Consultant Gastroenterologist, Spire Roding Hospital Dr Katherine Groves, Consultant Microbiologist, Homerton University Hospital Foundation Trust Jyoti Gupta, Senior Prescribing Advisor, NHS Camden Clinical Commissioning Group Dr Diane Harris, Lead Antimicrobial Pharmacist, NHS Southern Derbyshire Clinical Commissioning Group Hazel Steele, Specialist Pharmacist – Antimicrobials (Primary Care), NHS Tayside Dr Brendan Healy, Consultant in Microbiology and Infectious Diseases, Public Health England Dr Mathis Heydtmann, Consultant Hepatologist and Gastroenterologist, NHS Greater Glasgow and Clyde Dr Simon Hill, Consultant Microbiologist/Director of Infection Prevention and Control, Poole Hospital NHS Foundation Trust Prof Amanda Howe, Professor of Primary Care, University of East Anglia Dr Subash Jayakumar, General Practitioner, NHS Brent Clinical Commissioning Group Hannah Jones, Practice Pharmacist, IntraHealth Dr Priya Khanna, Consultant Microbiologist, London North West Healthcare NHS Trust Suzanne Lever, Pharmaceutical Advisor, Barnet Clinical Commissioning Group Michelle Liddy, Regional Technical Advisor, National Institute for Health and Care Excellence Hao Lu, Pharmacy Manager, United Family Healthcare Ayuen Lual, Features Editor, Society for Applied Microbiology Brian MacKenna, Deputy Head of Medicines Management, NHS Islington Clinical Commissioning Group Dr Sarah Meisner, Consultant Microbiologist, Royal United Hospitals NHS Foundation Trust Dr Alastair Miller, Consultant Physicians, Royal Liverpool and Broadgreen University Hospitals NHS Trust Layla Mohammadi, Lead Pharmacist – Antimicrobials, Lewisham and Greenwich NHS Trust Dr Rohinton Mulla, Lead Consultant Medical Microbiologist, Luton and Dunstable Hospital NHS Foundation Trust Dr Aaron Nagar, Consultant Microbiologist, Belfast Health and Social Care Trust Dr John O’Donohue, Consultant Physician and Gastroenterologist, Lewisham Healthcare NHS Trust Dr Ewan Olson, Consultant Microbiologist, NHS Lothian Dr Tamsin Oswald, Consultant Microbiologist, Northumbria Healthcare NHS Foundation Trust Elizabeth Ozogolu, Senior Prescribing Advisor, City and Hackney Clinical Commissioning Group Sarah Partridge, Antimicrobial Pharmacist, Nottingham University Hospitals NHS Trust Dr Terry Riordan, Consultant Medical Microbiologist, Royal Devon and Exeter Healthcare NHS Trust Dr Andrew Stacey, Consultant Microbiologist, Royal Berkshire NHS Foundation Trust Dr Rebecca Tilley, Consultant Microbiologist (Antibiotic Lead), West Suffolk NHS Foundation Trust Jane Usher, Biomedical Head of Serology/Virology, Public Health England Dr Chloe Walsh, Microbiology Registrar, Leeds Teaching Hospitals NHS Trust Rob Wise, Medicines Management Pharmacist, NHS Bassetlaw Clinical Commissioning Group Primary Care Clinicians from Concord Medical Centre, Bristol Primary Care Clinicians from Hanham Health Centre, Bristol Members of the Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection (ARHAI) Members of the British Infection Association (BIA) Members of the British Society for Antimicrobial Chemotherapy (BSAC) Members of the British Society of Gastroenterology (BSG) Members of the Public Health England (PHE) Standards Unit Members of the Royal College of General Practitioners (RCGP) Members of the Royal College of Nursing (RCN) Any conflicts of interest have been declared prior to the development and dissemination of this guidance. Abbreviations 13C = 13Carbon BD = Twice daily CI = Confidence interval CLAR = Clarithromycin CYP2C19 = Cytochrome P450 2C19 DU = Duodenal ulcer ECP = Enhanced compliance programme ELISA = Enzyme-linked immunosorbent assay g = Gram GORD = Gastro-oesophageal reflux disease GU = Gastric ulcer gyrA = DNA gyrase subunit A H2A = Histamine H2-receptor antagonist HP = Helicobacter pylori HTA = Health technology assessment IgA = Immunoglobulin A IgG = Immunoglobulin G IgM = Immunoglobulin M ITT = Intention to treat LR+ = Positive likelihood ratio LR- = Negative likelihood ratio LRs = Likelihood ratios MALToma = Mucosa-associated lymphoid tissue lymphoma MIC = Minimum inhibitory concentration mg = Milligram MZ = Metronidazole NPV = Negative predictive value NSAID = Non-steroidal anti-inflammatory drug pH = Potential of hydrogen PPI = Proton pump inhibitor QALYs = Quality adjusted life years QDS = Four times daily RR = Relative risk SAT = Stool antigen test UBT = Urea breath test UHD = Ulcer healing drug Yüklə 136,75 Kb. 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