The effects of diabetes mellitus include long-term damage, dysfunction and failure of various organs


About 80% of adults apparently with recently diagnosed Type 2 diabetes but with GAD auto-antibodies (i.e. LADA) progress to insulin requirement within 6 years



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About 80% of adults apparently with recently diagnosed Type 2 diabetes but with GAD auto-antibodies (i.e. LADA) progress to insulin requirement within 6 years.

  • About 80% of adults apparently with recently diagnosed Type 2 diabetes but with GAD auto-antibodies (i.e. LADA) progress to insulin requirement within 6 years.

  • The potential value of identifying this group at high risk of progression to insulin dependence includes:

    • the avoidance of using metformin treatment
    • the early introduction of insulin therapy


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