Hydroxylation of procollagen



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Hydroxylation of procollagen



PROLINE --> HYDROXYPROLINE

  • PROLINE --> HYDROXYPROLINE

  • TRYPTOPHAN --> SERATONIN

  • TYROSINE --> NOREPINEPHRINE

  • OSTEOBLASTS --> WOUND REPAIR

  • VASO-HUMORAL --> BLOOD FLOW

  • TOXICANTS -->MIXED Fn OXIDASES

  • STEROIDS -->STEROLS

  • Fe3+ -->Fe2+

  • Cu2+ -->Cu1+

  • Se4+ --> Se2+

  • CHOLESTEROL -> BILE ACIDS







Ascorbic acid also provides the reducing factor to convert tyrosine to the hormone norepinephrine.

  • Ascorbic acid also provides the reducing factor to convert tyrosine to the hormone norepinephrine.



Osteoblasts are the first cells formed in tissue wound repair, and cellular restructure. Ascorbic acid is involved in the synthesis of hydroxyproline amino acid that is a major component of the cellular membrane.

  • Osteoblasts are the first cells formed in tissue wound repair, and cellular restructure. Ascorbic acid is involved in the synthesis of hydroxyproline amino acid that is a major component of the cellular membrane.



The elastic characteristics of the vascular system are determined by the hydroxyproline constituants, which are dependent upon ascorbate reserves during formation of the fiberous tissues.

  • The elastic characteristics of the vascular system are determined by the hydroxyproline constituants, which are dependent upon ascorbate reserves during formation of the fiberous tissues.



The first tissue reaction to toxicants is hydroxylation of the chemical compounds involved. The mixed function oxidases require ascorbate in the oxidation-reduction process involved.

  • The first tissue reaction to toxicants is hydroxylation of the chemical compounds involved. The mixed function oxidases require ascorbate in the oxidation-reduction process involved.



The conversion of steroids to sterols involves ascorbic acid in the hydroxylation in the oxidation reduction process involved.

  • The conversion of steroids to sterols involves ascorbic acid in the hydroxylation in the oxidation reduction process involved.



Ascorbic acid is a reducing agent for the conversion of ferric to ferrous ions.

  • Ascorbic acid is a reducing agent for the conversion of ferric to ferrous ions.



Ascorbic acid acts as a reducing agent to change copper state in compounds involved in intermediary metabolism.

  • Ascorbic acid acts as a reducing agent to change copper state in compounds involved in intermediary metabolism.



Ascorbic acid acts as the major intracellular reducing agent to reduce selenium to an active state for glutathione peroxidase reduction of lipid peroxides to alcohols.

  • Ascorbic acid acts as the major intracellular reducing agent to reduce selenium to an active state for glutathione peroxidase reduction of lipid peroxides to alcohols.


































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