Interactions Studies conducted with Hypnovel Ampoules
Ketoconazole increased the plasma concentration of intravenous midazolam by 5-fold while the terminal half-life increased by about 3-fold. If parenteral midazolam is co-administered with the strong CYP3A inhibitor ketoconazole, it should be done in an...
Cimetidine and ranitidine
HIV Protease Inhibitors
Saquinavir and other HIV protease inhibitors: Upon co-administration with ritonavir boosted lopinavir, the plasma concentrations of intravenous midazolam increased by 5.4-fold, associated with a similar increase in terminal half-life. If parenteral mi...