898.12 Individual microvascular units are critical to
cardiac performance.
S. Egginton, D. Hauton, J. Winter and
R.D. Evans. Univ. of Birmingham, Univ. of Leicester and Oxford
Univ., U.K.
B29
898.13 Influence of short-term high salt diet and acute
exercise on microvascular reactivity in humans.
A. Cavka, I.
Grizelj, M. Goslawski, I. Drenjancevic, J-T. Bian and S.A.
Phillips. Sch. of Med., JJ Strossmayer Univ. of Osijek, Croatia
and Col. of Applied Hlth. Sci., Univ. of Illinois at Chicago.
B30
898.14 The effects of AT1 receptor blockade on skin
microcirculatory blood flow and thromboxane A2 production
in young healthy women.
A. Cavka, I. Grizelj, A. Cosic, A.
Koller, B. Jelakovic, J.H. Lombard, S.A. Phillips and I.
Drenjancevic. Sch. of Med., JJ Strossmayer Univ. of Osijek,
Croatia, Med. Sch., Univ. of Pecs, Hungary, Univ. Hosp. Ctr.
Zagreb, Croatia, Med. Col. of Wisconsin and Col. of Applied
Hlth. Sci., Univ. of Illinois at Chicago.
B31
898.15 Role of K-channels in microvascular flow-
induced dilation of subcutaneous and visceral arterioles in
human obesity.
I. Grizelj, A. Cavka, J-T. Bian, I. Drenjancevic
and S.A. Phillips. Sch. of Med., Univ. of Osijek, Croatia and
Univ. of Illinois at Chicago.
B32
898.16 Flow-induced structural adaptation of tumor
vasculature by selective micro-laser ablation.
G. Gruionu, L.
Gruionu and L.L. Munn. Massachusetss Gen. Hosp. and
Harvard Med. Sch., Charlestown, Univ. of Med. and Pharm. of
Craiova and Univ. of Craiova, Romania.
B33
898.17 Effect of SNAP-generated NO on PO
2
and VO
2
in contracting skeletal muscle.
A.S. Golub, B.K. Song and
R.N. Pittman. Virginia Commonwealth Univ.
B34
898.18 The effects of brief ischemia and reperfusion
on interstitial PO
2
in the rat spinotrapezius muscle.
S.C. Dodhy,
A.S. Golub and R.N. Pittman. Virginia Commonwealth Univ.
B35
898.19 Flow modulation and recruitment in a
theoretical model for blood flow regulation in heterogeneous
microvascular networks.
B.C. Fry and T.W. Secomb. Univ. of
Arizona.
B36
898.20 Evidence of centrally-induced cholinergic
vasodilatation in skeletal muscle during voluntary one-legged
cycling and motor imagery.
K. Ishii, K. Matsukawa, N. Liang,
K. Endo, M. Idesako, T. Kataoka, K. Ueno and H. Hamada.
Grad. Sch. of Biomed. and Hlth. Sci., Hiroshima Univ.
B37
898.21 Effects of perfluorocarbon emulsions on
microvascular blood flow and O
2
transport in a model of severe
arterial gas embolism.
L. Torres, B. Spiess and I. Torres Filho.
Virginia Commonwealth Univ.
B38
898.22 Enhanced oxygen transport by perfluorocarbon
emulsion mixed with flowing human blood studied in vitro.
I.
Torres Filho, J.R. Pedro, S. Narayanan, S. Roseff, N. Nguyen,
B. Berger, L. Torres and B. Spiess. Virginia Commonwealth
Univ.
B39
898.23 Effects of genetic strain and light intensity
on blood physiological variables of broilers grown to heavy
weights.
H.A. Olanrewaju, J.L. Purswell, S.D. Collier and S.L.
Branton. USDA, Starkville, MS.
PHYSIOLOGY MONDAY
291
M
O
N
899. MICROVASCULAR MECHANICS/
HEMODYNAMICS/RHEOLOGY
Poster
(Sponsored by: The Microcirculatory Society)
m
on
. 7:30
am
—B
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C
onvention
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C
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,
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Presentation time: 12:45
pm
-3:00
pm
B40
899.1
Transmission of pulsatility in the
microcirculation: Where and how damping occurs?
Q. Pan, R.
Wang, B. Reglin, J. Yan, G. Ning and A.R. Pries. Zhejiang
Univ. and Hosp., China and Charité and German Heart Inst.,
Berlin.
B41
899.2
Numerical study of blood flow in a microchannel
bifurcation with the large deformation model.
S.S. Ye, M. Ju,
Y.C. Ng, K.S. Tan and S. Kim. Natl. Univ. of Singapore.
B42
899.3
Topology, angioarchitecture and
hemodynamics of chick chorioallantoic vascular networks.
M. Maibier, B.E. Reglin, B. Nitzsche, M. Höpfner and A.R.
Pries. Charité Med. Univ. Berlin.
B43
899.4
A mechanistic collagen recruitment model can
explain passive property differences in resistance arteries from
salt-sensitive, fawn-hooded and Brown Norway rats on low
salt diets.
Q. Hao, B.D. Weinberg, J.H. Lombard and B.E.
Carlson. Med. Col. of Wisconsin.
900. MICROVASCULAR PATHOPHYSIOLOGY —
PHARMACOLOGY, THERAPEUTICS AND
TRANSLATIONAL ASPECTS
Poster
(Sponsored by: The Microcirculatory Society)
m
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. 7:30
am
—B
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C
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a-B
Presentation time: 12:45
pm
-3:00
pm
B44
900.1
Mechanistic studies of AVE3085 against
homocysteine in endothelial protection.
Q. Yang, H-M. Xue
and C-M. Yu. The Chinese Univ. of Hong Kong, TEDA Intl.
Cardiovasc. Hosp., Med. Col., Nankai Univ., Hong Kong and
Hebei Med. Univ., China.
B45
900.2
In isolated vessels H
2
S is a less effective
scavenger of exogenous superoxide than SOD.
Z. Springo, M.
Solymar, P. Cseplo, P. Toth, G. Berta, J. Hamar and A. Koller.
Univ. of Pecs Med. Sch., Hungary, Univ. of Oklahoma Hlth. Sci.
Ctr. and New York Med. Col., Valhalla.
B46
900.3
cAMP agonists stabilize the microvascular
barrier in ischemia-reperfusion.
A.H. Korayem, D.D. Kim, R.J.
Rana, M. Paris-Roncayolo and W.N. Duran. Grad. Sch. of
Biomed. Sci., UMDNJ-New Jersey Med. Sch.
B47
900.4
Platelets of humans with type 2 diabetes
(DM2) exhibit fewer prostacyclin receptor (IPR) binding sites
as well as decreased iloprost-mediated cAMP accumulation.
S.
Knebel, R. Sprague, M. Ellsworth and A. Stephenson. Saint
Louis Univ.
B48
900.5
Glucagon-like peptide-1 attenuates agonist-
stimulated cytosolic free calcium ([Ca
2+
]
i
) signaling and the
production of F2
a-isoprostane in endothelial cells. V.A.
Richardson, C.S. Weber, R.M. Lynch and B.B. Dokken. Univ.
of Arizona.
B49
900.6
Depressive symptoms, inflammation and
microvascular dysfunction: presence of a gender disparity.
S.C.
Stanley, J.T. Butcher, S.J. Frisbee, A.C. d’Audiffret and J.C.
Frisbee. West Virginia Univ.
B50
900.7
SKA-31, a positive modulator of SK
Ca
andIK
Ca
channels, increases systemic conductance and lowers arrterial
pressure in an anesthetized pig model.
R.C. Mishra, J.
Mitchell, H. Wulff, I. Belenkie, J.V. Tyberg and A.P. Braun.
Univ. of Calgary, Canada and Univ. of California, Davis.
B51
900.8
Loss of endothelial caveolae leads to eNOS
uncoupling and impaired flow-mediated dilation in human
coronary arterioles in diabetes.
J. Cassuto, A. Feher, A. Szabo
and Z. Bagi. Med. Col. of Georgia.
B52
900.9
Adipose tissue artery-derived TNF impairs
dilation of skeletal muscle resistance arteries in obesity.
A.
Feher, A. Szabo and Z. Bagi. Med. Col. of Georgia.
B53
900.10 Effects of resuscitation fluids on endothelial
glycocalyx and coagulation in severe hemorrhagic shock.
L.
Torres, J. Sondeen, L. Ji, M. Dubick and I. Torres Filho. U.S.
Army Inst. of Surg. Res., San Antonio.
B54
900.11 Effects of resuscitation fluids following
hemorrhagic shock on venular glycocalyx in rats.
I. Torres
Filho, L. Torres, J. Sondeen, L. Ji and M. Dubick. U.S. Army
Inst. of Surg. Res., Fort Sam Houston, TX.
901. VASOMOTOR CONTROL: ENDOTHELIUM/
SMOOTH MUSCLE/NERVES
Poster
(Sponsored by: The Microcirculatory Society)
m
on
. 7:30
am
—B
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C
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& e
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C
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Presentation time: 12:45
pm
-3:00
pm
B55
901.1
Inhibition of neutral sphingomyelinase prevents
high pressure-induced shift in the mediator of endothelium-
dependent dilation from NO to H
2
O
2
.
J.K. Freed, A.M. Beyer
and D.D. Gutterman. Med. Col. of Wisconsin.
B56
901.2
Sensory nerve-dependent prolonged opening
of pannexin-1-based channels controls eNOS phosphorylation
in mesenteric arteries.
P. Gaete, M. Lillo and X. Figueroa.
Pontifical Catholic Univ. of Chile.
B57
901.3
Aging attenuates spontaneous endothelial
Ca
2+
events with altered perivascular nerve function in mouse
mesenteric arteries in vivo.
E.B. Westcott and S.S. Segal.
Univ. of Missouri-Columbia.
B58
901.4
Metabolic syndrome and endothelin-1
mediated vasoconstrictor tone in overweight/obese adults.
N.G.
Rocha, D.L. Templeton, J.J. Greiner, B.L. Stauffer and C.A.
DeSouza. Fluminense Fed. Univ., Brazil and Univ. of Colorado
at Boulder.
B59
901.5
The effect of chronic low grade hyperglycemia
on basal nerve blood flow values in Sprague-Dawley rats.
T.D.
Olver, K.N. Grise, M.M. McDonald, A. Dey, E.G. Noble, C.W.J.
Melling, J.C. Lacefield and J.K. Shoemaker. Western Univ.,
Canada.
B60
901.6
Simultaneous measurement of microvascular
blood flux and tissue oxygenation in human skin.
G. Clough, K.
Kuliga, K. McCormick, R. Gush and A. Chipperfield. Univ. of
Southampton and Moor Instruments Ltd., Axminster, U.K.
MONDAY PHYSIOLOGY
292
B61
901.7
Interference with PPAR
g in endothelium
accelerates angiotensin II-mediated vascular dysfunction.
C.
Hu, F.M. Faraci and C.D. Sigmund. Roy J. & Lucille A. Carver
Col. of Med., Univ. of Iowa.
B62
901.8
Multiscale computational models of
microvascular reactivity from ion channels to intercellular
signaling.
A. Kapela, J. Parikh and N.M. Tsoukias. Florida Intl.
Univ.
B63
901.9
Vascular endothelial cell protein expression
of adiponectin is related with vascular endothelial function in
healthy older adults.
J-K. Yoo, M-H. Hwang, H-K. Kim, M.J.
Luttrell, T.H. Meade, M.W. English and D.D. Christou. Univ.
of Florida and Texas A&M Univ. Hlth. Sci. Ctr.
B64
901.10 TRPV4-mediated responses of the rat isolated
cremaster muscle artery.
T.V. Murphy, A. Kanagarajah, S.
Senadheera and S.L. Sandow. Sch. of Med. Sci., Univ. of New
South Wales, Australia.
B65
901.11 Differential impact of dilator stimuli on
increased myogenic activation of cerebral and skeletal muscle
resistance arterioles in obese Zucker rats.
J.T. Butcher, S.C.
Stanley and J.C. Frisbee. West Virginia Univ.
B66
901.12 Novel methodology to simultaneously image
endothelial and smooth muscle function in pressurized arteries.
C. Wilson, C. Saunter, J.M. Girkin and J.G. McCarron.
Strathclyde Univ. and Durham Univ., U.K.
B67
901.13 Positive feedback influence of K
Ca
3.1 channels
on stimulated endothelial Ca
2+
dynamics.
M.S. Taylor, R.
Köhler, F. Michael and X. Qian. Univ. of South Alabama, Univ.
of Southern Denmark and ARIAD and Aragonese Inst. of Hlth.
Sci., Zaragoza, Spain.
B68
901.14 Crosstalk between NO and cAMP signaling
in basilar arteries from young and old mice.
G. Pfitzer, L.T.
Lubomirov, J. Welter, K. Weckmueller, N. Todorovic and S.
Papadopoulos. Univ. of Cologne.
B69
901.15 Neuronal nitric oxide synthase inhibition
and regional sympathetic nerve discharge: implications for
peripheral vascular control.
S.W. Copp, D.M. Hirai, G.E. Sims,
T.I. Musch, M.J. Kenney and D.C. Poole. Kansas State Univ.
B70
901.16 Vasodilators produced during active hyperemia
interact: potassium attenuates the vasodilatory effect of nitric
oxide.
I.R. Lamb and C.L. Murrant. Univ. of Guelph, Canada.
902. MICROCIRCULATION II
Poster
(Sponsored by: The Microcirculatory Society)
m
on
. 7:30
am
—B
oston
C
onvention
& e
xhiBition
C
enter
,
e
xhiBit
h
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a-B
Presentation time: 12:45
pm
-3:00
pm
B71
902.1
Mechanisms underlying combined effects
of hypertension and hypercholesterolemia on microvascular
function.
A. Yildirim, A.L. Dozier and D.N. Granger. LSU Hlth.
Sci. Ctr., Shreveport.
B72
902.2
Evaluation of the subacute systemic thrombotic
and organ toxicity of nicotine in mice.
M.A. Fahim, A. Nemmar,
S. Al-Salam, S. Dhanasekaran, M. Shafiullah, J. Yasin and
M.Y. Hasan. Col. of Med. and Hlth. Sci., Al Ain, United Arab
Emirates.
B73
902.3
Role of thrombospondin-1 in the remodeling
induced by a chronic increase in flow in resistance arteries.
C. Grenier, A. Caillon, L. Grimaud, A. Ayer, B. Toutain, O.
Blanc-Brude, D. Henrion and L. Loufrani. CNRS, INSERM
1083, Angers and PARCC INSERM 970, Paris.
B74
902.4
Contribution of the actin cytoskeleton to the
viscoelastic characteristics of inwardly remodeled arterioles.
J.A. Castorena-Gonzalez, M.C. Staiculescu, G. Zhao and
L.A. Martinez-Lemus. Univ. of Missouri-Columbia.
B75
902.5
Post-nodal lymphatic vessels adapt to
sustained high flow conditions by becoming weaker pumps.
R.M. Dongaonkar, T.L. Nguyen, C.M. Quick, G.A. Laine, E.
Wilson, C. Heaps, J. Hardy and R.H. Stewart. Texas A&M
Univ.
B76
902.6
Intrinsic balance of small artery active and
passive diameter-tension relations.
B.G. Tuna, E.N.T.P. Bakker
and E. VanBavel. Acad. Med. Ctr., Amsterdam.
B77
902.7
Deletion of macrophage focal adhesion kinase
signaling impairs neither arteriogenesis nor angiogenesis in
the mouse ischemic hindlimb model.
K.P. Murrell, J. Meisner,
A. Bouton and R. Price. Univ. of Virginia.
B78
902.8
The impaired glycocalyx increases the
endothelial susceptibility to shear stress resulting in augmented
nitric oxide production in microvessels of diabetic rats.
S. Xu
and P. He. West Virginia Univ.
B79
902.9
Comparing the degree of collateral vessel
dilation necessary to compensate for a major arterial occlusion
in mouse and man.
J. Arciero, M. DiStasi and J. Unthank.
Indiana Univ.-Purdue Univ. Indianapolis and Indiana Univ. Sch.
of Med.
B80
902.10 Increased local production of homocysteine
elicits endothelial dysfunction via a mechanism of angiotensin-
dependent oxidative stress.
D. Sun, A. Huang and T.H. Hintze.
New York Med. Col.
B81
902.11 Estrogen-dependent methylation of sEHh gene
in mesenteric arteries of mice.
A. Huang and D. Sun. New York
Med. Col.
B82
902.12 Drag reducing polymers diminishing the near
vessel wall cell poor region.
J. Brands, M. Kameneva and J.
Pacella. Univ. of Pittsburgh.
B83
902.13 Pressor and renal regional hemodynamic
effects of urotensin II in neonatal pigs.
H. Soni and A. Adebiyi.
Univ. of Tennessee Hlth. Sci. Ctr.
B84
902.14 Treadmill running improves diabetes-induced
capillary regression in skeletal muscle through activation
of VEGF and angiopoietin pathways without inhibition of
thrombospondin-1.
H. Fujino, H. Kondo, S. Murakami, M.
Tanaka, F. Nagatomo, N. Fujita and A. Ishihara. Kobe Univ.,
Nagoya Women’s Univ. and Kyoto Univ., Japan.
POSTER PRESENTERS:
UPLOAD YOUR POSTER
Where: E-Poster Counter, Sun. – Tue. Hall A; Wed. Hall C
Deadline: Tue., April 23, 5:00
pm
; Wed., April 24, 3:00
pm
Uploaded posters will be available online to all
registered attendees following the meeting at
www. experimentalbiology.org
PHYSIOLOGY MONDAY
293
M
O
N
903. BLOOD PRESSURE REGULATION II
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
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C
enter
,
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a-B
Presentation time: 12:45
pm
-3:00
pm
B85
903.1
Effects of time of day on 24-h postexercise
blood pressure and mood in normotensive humans.
R. Sone, F.
Yamazaki and N. Tan. Univ. of Yamaguchi and Univ. of Occup.
and Envrn. Hlth., Japan.
B86
903.2
Combined exercise training attenuates cardiac
and autonomic dysfunctions in an experimental model of
menopause and diabetes.
I.C. Sanches, F.F. Conti, M.R.R.
Soares, H.G. Quinteiro, R. Sirvente, M-C. Irigoyen and K.
De Angelis. Univ. Nove de Julho and Heart Inst., São Paulo.
B87
903.3
Comparison of cardiovascular responses to
yoga and slow paced breathing.
S. Bertisch, J. Hamner, C.
Tan and J.A. Taylor. Beth Israel Deaconess Med. Ctr., Harvard
Med. Sch., Brookline and Spaulding Rehabil. Hosp., Harvard
Med. Sch., Cambridge.
B88
903.4
In vivo assessment of blood pooling and
muscle pump dynamics under orthostatic stress.
C. Leguy,
A. Blaber, J. Kuemmel, L. Beck, J. Zange and J. Rittweger.
Simon Fraser Univ., Canada and German Aerospace Inst.,
Cologne.
B89
903.5
High-intensity aerobic training restores the
ability to modulate sympathetic vasoconstriction in contracting
skeletal muscle of hypertensive and healthy middle-aged
individuals.
S.P. Mortensen, M. Nyberg, L. Gliemann,
P. Thaning and Y. Hellsten. Rigshospitalet and Univ. of
Copenhagen.
B90
903.6
Variability in the strength of AT
1
R Ca
2+
signaling.
L. Scott, K. Bernhem, H. Brismar and A. Aperia. Karolinska
Inst. and Royal Inst. of Technol., Stockholm.
B91
903.7
Bifurcating response to hemorrhage in a
population of mathematical models of the circulation.
W.A.
Pruett, G. Husband, K. Bellamy, M. Dakhlalla, T. Coleman
and R.L. Hester. Univ. of Mississippi Med. Ctr., Vanderbilt Univ.
and Mississippi State Univ.
B92
903.8
Increased expression of prorenin receptor
in the NTS of spontaneously hypertensive rats may be a
compensatory mechanism of hypertension.
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