1117. ASSESSING POSTGANGLIONIC SYMPATHETIC
NEURONAL DISCHARGE PATTERNS:
IMPLICATIONS FOR UNDERSTANDING
ABERRANT SYMPATHETIC OUTFLOW
(POSTERS)
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B109
1117.1 A case for a standardized method for the
normalization of muscle sympathetic nerve activity amplitude.
D.W. White, V.L. Kay, G. Moralez, W.L. Eubank and P.B.
Raven. Univ. of North Texas Hlth. Sci. Ctr. at Fort Worth.
B110
1117.2 Augmented response of renal sympathetic
nerve single units to chemoreceptor stimuli in rabbits with
angiotensin-induced hypertension.
G.A. Head, S.L. Burke
and E.V. Lukoshkova. Baker IDI Heart and Diabetes Inst.,
Melbourne and Natl. Cardiol. Res. Ctr., Moscow.
B111
1117.3 Sympathetic vascular transduction following
spontaneous MSNA bursts is augmented in young black men.
D.P. Credeur, S.W. Holwerda, S.T. Fairfax, D.M. Keller and
P.J. Fadel. Univ. of Missouri-Columbia and Univ. of Texas at
Arlington.
B112
1117.4 Sympathetic and cardiovagal baroreflex
sensitivity in humans: comparison of Valsalva’s maneuver
and spontaneous methodologies.
H. Yang and J.R. Carter.
Michigan Technol. Univ.
B113
1117.5 Sympathetic nerve activity and systemic
arterial pressure during obstructive sleep apnea in conscious
rats.
C. Sukeguchi and K. Miki. Nara Women’s Univ., Japan.
B114
1117.6 Effect of mental stress on skin sympathetic
nerve activity: are responses reproducible?
C.A. Ray, C.L.
Sauder and M.D. Muller. Penn State, Hershey.
B115
1117.7 Evaluation of muscle sympathetic nerve
activity in patients with chronic severe aortic insufficiency.
S.B.P.C. Souza, T.A.D. Accorsi, M. Katz, O.C. Bezerra, G.A.
Neves, M.B.P. Grinberg, F.M. Consolim-Colombo and F.B.P.
Tarasoutchi. Clin Hosp., Sch. of Med., Univ. of São Paulo.
1118. NEURAL CONTROL OF CARDIOVASCULAR
FUNCTION
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B116
1118.1 The effect of gender on sympathetic neural
responses to cold pressor testing in hypertensive seniors.
J.M.
Hendrix, T. Bivens, S. Best, Y. Okada, B.D. Levine and Q. Fu.
Univ. of Texas Southwestern Med. Ctr. and Inst. for Exercise
and Envrn. Med., Dallas.
B117
1118.2 Macrophage migration inhibitory factor
decreases neuroinflammation in the solitary tract nucleus
of spontaneously hypertensive rats.
A.H. Freiria-Oliveira,
G.T. Blanch, H. Li, D.S.A. Colombari, E. Colombari and C.
Sumners. FOAR-UNESP, Brazil, Univ. of Florida and Southern
Med. Univ., China.
LAST DAY TO
VISIT EXHIBITS
Tuesday, April 23
9:00 AM – 4:00 PM
PHYSIOLOGY TUESDAY
385
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B118
1118.3 Elderly blacks have a similar sympathetic
neural responsiveness but greater pressor response to cold
stress than elderly whites.
Y. Okada, J. Edwards, S.S. Jarvis,
S.A. Best, R.L. Meier, T.B. Bivens, W. Vongpatanasin, B.D.
Levine and Q. Fu. Texas Hlth. Presbyterian Hosp. Dallas and
Univ. of Texas Southwestern Med. Ctr.
B119
1118.4 P2Y1-receptors are expressed by C1 cells and
regulate peripheral chemoreceptor modulation of breathing and
blood pressure.
I.C. Wenker, C.R. Sobrinho, A.C. Takakura,
T.S. Moreira and D.K. Mulkey. Univ. of Connecticut and Univ.
of São Paulo.
B120
1118.5 Activation of NMDA receptors results in
different autonomic and cardiovascular responses along
the rostrocaudal axis of the insular cortex.
F.R. Marins, M.
Limborço-Filho, G.C. Vaz, C.H. Xavier and M.A.P. Fontes.
Fed. Univ. of Minas Gerais, Brazil.
B121
1118.6 Distension of central great vein decreases
sympathetic outflow in humans.
J. Cui, Z. Gao, C. Blaha, J.
Mast, M.D. Herr and L.I. Sinoway. Penn State Col. of Med.
B122
1118.7 Cardiovascular responses during static skeletal
muscle contraction following neuronal NOS blockade within the
ventrolateral medulla.
A. Ally and T.J. Maher. South Col. Sch.
of Pharm., KY and Massachusetts Col. of Pharm. & Hlth. Sci.
B123
1118.8 Respiratory influences on muscle sympathetic
nerve activity and limb vascular conductance in the steady-
state.
J.K. Limberg, B.J. Morgan, W.G. Schrage and J.A.
Dempsey. Sch. of Educ. and Sch. of Med. and Publ. Hlth., Univ.
of Wisconsin-Madison.
B124
1118.9 The exaggerated exercise pressor reflex in
heart failure: MAPK activation in peripheral dorsal root ganglia.
H. Wang, W. Wang, G.J. Rozanski and I.H. Zucker. Univ. of
Nebraska Med. Ctr.
B125
1118.10 Afferent vagal nerve stimulation resets the
baroreflex neural arc and inhibits sympathetic nerve activity.
K. Saku, K. Sakamoto, K. Hosokawa, T. Kakino, M. Ikeda,
Y. Oga, A. Nishizaki, T. Ide and K. Sunagawa. Kyushu Univ.,
Japan.
B126
1118.11 Hyperadrenergic activity and the postural
tachycardia syndrome.
D.A. Low, M.A. Akhtar, V. Iodice, L.
Watson and C.J. Mathias. Imperial Col. London and Natl.
Hosp. for Neurol. and Neurosurg., London.
B127
1118.12 Elevated brain-derived neurotrophic factor
levels in the paraventricular nucleus increase blood pressure,
heart rate and indices of sympathetic activity.
B. Erdos, I.
Backes, M.L. McCowen and D.A. Scheuer. Univ. of Florida.
B128
1118.13 Severe hemorrhage attenuates
cardiopulmonary chemoreflex control of renal and adrenal
sympathetic nerves via adenosine operating in the nucleus of
the solitary tract.
Z. Minic, C. Li, D.S. O’Leary and T.J. Scislo.
Wayne State Univ. Sch. of Med.
B129
1118.14 Sympathoinhibition in men during paced
breathing at 0.25 Hz.
N. Coverdale, C.W. Usselman, T.I.
Gimon, C.A. Nielsen, T.A. Luchyshyn and J.K. Shoemaker.
Western Univ., Canada.
B130
1118.15 Immunohistochemistry confirms the functional
evidence that the cardiopulmonary chemoreflex pathways in
the caudal nucleus of the solitary tract are directly inhibited by
A
1
adenosine receptors and indirectly inhibited by A
2a
receptor
Z. Minic, D.S. O’Leary, H.G. Goshgarian and T.J. Scislo.
Wayne State Univ. Sch. of Med.
B131
1118.16 Muscle metaboreflex-induced increases in
ventricular performance are limited in hypertension due to
exaggerated coronary vasoconstriction.
M.D. Spranger, J.A.
Sala-Mercado, J. Kaur, R. Abu-Hamdah and D.S. O’Leary.
Wayne State Univ. Sch. of Med.
B132
1118.17 Lack of interaction of co-existing TRPV1 and
CB1 receptors indicates differential control of separate basal
and synchronous glutamate release mechanisms in the
solitary tract nucleus.
M.C. Andresen, M.E. Hofmann and J.A.
Fawley. Oregon Hlth. & Sci. Univ.
B133
1118.18 Individual differences in cardiac and vascular
components of the pressor responses to isometric handgrip
exercise in humans.
K. Watanabe, M. Ichinose, R. Tahara and
T. Nishiyasu. Univ. of Tsukuba and Meiji Univ., Japan.
B134
1118.19 Hormone-phase dependence of muscle
sympathetic nerve activity in young healthy women using
hormonal contraceptives.
C.W. Usselman, T.A. Luchyshyn, T.I.
Gimon, C.A. Nielson, S.H.M. Van Uum and J.K. Shoemaker.
Sch. of Kinesiol. and Schulich Sch. of Med. and Dent., Western
Univ., Canada.
B135
1118.20 Rheumatoid arthritis and arterial baroreflex
function.
A.M. Adlan, G. Kitas, J.F.R. Paton, G.Y.H. Lip and
J.P. Fisher. Univ. of Birmingham, Russells Hall Hosp., Dudley,
Univ. of Bristol and City Hosp., Birmingham, U.K.
B136
1118.21 Diminished baroreflex function following
ovariectomy is a consequence of the reduced excitability
of a sex-specific population of low threshold myelinated
baroreceptor afferents in the rat.
G.C. Santa Cruz Chavez, B.
Li and J.H. Schild. Indiana Univ.-Purdue Univ. Indianapolis.
B137
1118.22 Auditory and visual stimuli evoke a
synchronized activation of sympathetic, respiratory and motor
outputs after disinhibition of midbrain colliculi.
F.C.F. Muller-
Ribeiro, M.P. Fontes, R.A.L. Dampney and A.K. Goodchild.
Macquarie Univ., Australia, Fed. Univ. of Minas Gerais, Brazil
and Sydney Univ.
B138
1118.23 Influence of age on respiratory modulation
of muscle sympathetic nerve activity and blood pressure
in humans.
A. Shantsila, D.B. McIntyre, G.Y.H. Lip, J.F.R.
Paton, P.J. Fadel, A.E. Pickering and J.P. Fisher. Univ.
of Birmingham and City Hosp., U.K., Univ. of Bristol Sch. of
Physiol. & Pharmacol. and Univ. of Missouri-Columbia.
B139
1118.24 Gene expression of NMDA receptor subunits
using laser capture microdissection in the rostral ventrolateral
medulla of sedentary versus physically active rats.
M.
Subramanian, A.G. Holt and P.J. Mueller. Wayne State Univ.
B140
1118.25 Immunofluorescence identifies the
a1 subunit
of the GABA
A
receptor on spinally projecting neurons in rostral
ventrolateral medulla.
M.D. Dombrowski, I.J. Llewellyn-Smith
and P.J. Mueller. Wayne State Univ. Sch. of Med. and Flinders
Med. Ctr., Australia.
B141
1118.26 Water drinking enhances the gain of arterial
baroreflex control of muscle sympathetic nerve activity in
healthy humans.
L.C. Vianna, I.A. Fernandes, D.G. Martinez,
B.M. Silva, P.J. Fadel and A.C. Nobrega. Fluminense Fed.
Univ. and Salgado Oliveira Univ., Brazil and Univ. of Missouri-
Columbia.
B142
1118.27 Heart rate variability and cardiorespiratory
fitness in African American men.
R.L. Herron and M.R. Esco.
Univ. of Alabama and Auburn Univ. Montgomery.
B143
1118.28 Neurocardiovascular effects of V1b receptor
blockade within paraventricular nucleus in conscious Sprague
Dawley rats.
W.M. El Werfali, M. Maliszewska-Scislo, H.
Chen and N.F. Rossi. Wayne State Univ. and John D. Dingell
VA Med. Ctr.
B144
1118.29 Sympatho-inhibition in an ovine model of septic
shock: cardiovascular and renal effects.
C. May, R. Bellomo
and P. Calzavacca. Florey Inst. of Neurosci. and Ment. Hlth.
and Austin Hlth., Melbourne.
TUESDAY PHYSIOLOGY
386
B145
1118.30 Increasing leptin sensitivity via PTP1B deletion
does not increase blood pressure through an increased
sympathetic tone in mice on a Balb/c background.
B.R. Butler,
J.B. Norman, M.L. Tremblay and E.J. Belin de Chantemele.
Georgia Hlth. Sci. Univ. and McGill Univ.
B146
1118.31 Continuous and intermittent electrical
stimulation of the aortic depressor nerve in conscious rats:
time course of the hemodynamic responses.
H. Salgado, F.
Brognara, D.P.M. Dias, J.A. Castania and R. Fazan, Jr. Univ.
of São Paulo, Ribeirão Preto.
B147
1118.32 Technique-dependent considerations when
assessing racial differences in arterial baroreflex function.
D.M.
Keller, S.W. Holwerda, D.P. Credeur and P.J. Fadel. Univ. of
Texas at Arlington and Univ. of Missouri-Columbia.
B148
1118.33 Carotid baroreflex control of heart rate is
enhanced during whole-body heat stress.
D. Krnjajic, C.L.
Butts, W.S. Warren, M.R. Samels and D.M. Keller. Univ. of
Texas at Arlington.
B149
1118.34 Arterial baroreflex control of sympathetic
nerve activity during acute hypotension is enhanced in young
normotensive black men.
S.W. Holwerda, D.M. Keller, D.P.
Credeur and P.J. Fadel. Univ. of Missouri-Columbia and Univ.
of Texas at Arlington.
B150
1118.35 Astrocytes influence SON and PVN
neurosecretory and presympathetic neuronal excitability
via activation of an extrasynaptic NMDA/A-type K
+
channel
coupling mechanism.
K. Naskar and J.E. Stern. Georgia Hlth.
Sci. Univ.
B151
1118.36 A novel relationship between estrogen, insulin
resistance, and cardiovagal baroreflex sensitivity in obese
PCOS women.
J.A. Miner, J.C. Miner, V.E. Brunt, P.F. Kaplan
and C.T. Minson. Univ. of Oregon and Oregon Hlth. & Sci. Univ.
B152
1118.37 An inverse relationship between testosterone
and muscle sympathetic nerve activity: an investigation in lean
healthy females.
E.E. Madison, J.C. Miner, J.A. Miner, P.F.
Kaplan and C.T. Minson. Univ. of Oregon and Oregon Hlth. &
Sci. Univ.
B153
1118.38 The neurosteroid metabolite of progesterone,
3
a-OH-dihydroprogesterone, is required for attenuated
baroreflex mediated sympathoexcitation in pregnancy.
J.G.
Phaup, E.M. Hasser and C.M. Heesch. Univ. of Missouri-
Columbia.
B154
1118.39 Testosterone increases muscle sympathetic
nerve activity in young healthy males.
J.C. Miner, J.A. Miner,
P.F. Kaplan and C.T. Minson. Univ. of Oregon and Oregon
Hlth. & Sci. Univ.
B155
1118.40 Autonomic reflexes may contribute to the
symptomatology of mal de debarquement syndrome.
T.E.
Wilson, A.D. LePorte, K. Toma, J.S. Thomas and B.C. Clark.
Ohio Univ. Heritage Col. of Osteo. Med.
B156
1118.41 Mindfulness meditation lowers blood pressure
and sympathetic activity in hypertensive patients with chronic
kidney disease.
J. Park and S. Bauer-Wu. Emory Univ. Sch. of
Med. and Sch. of Nursing.
1119. NEURAL CONTROL OF CARDIOVASCULAR
FUNCTION: THE VASCULATURE
Poster
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B157
1119.1 Impaired hypoxic vasodilation in healthy older
adults: role for altered sympatho-adrenal control of vascular
tone.
J.C. Richards, A.R. Crecelius, B.S. Kirby, L.J. Garcia,
G.J. Luckasen, D.G. Larson and F.A. Dinenno. Colorado
State Univ. and Med. Ctr. of Rockies, Loveland, CO.
B158
1119.2 The role of
a-adrenergic receptors in mediating
beat-by-beat sympathetic vascular transduction in resting
humans.
S.T. Fairfax, D.P. Credeur, S.W. Holwerda, M.Y.
Zuidema, J.H. Medley, P.C. Dyke II and D.W. Wray. Univ. of
Missouri-Columbia and Univ. of Utah.
B159
1119.3 Alternative pathway to angiotensin converting
enzyme for angiotensin II generation in mouse mesenteric
artery.
C. Becari, M.A. Barbosa da Silva, H.C. Salgado,
R.C.A. Tostes, E.B. Oliveira and M.C.O. Salgado. Fac. of
Med. of Ribeirão Preto, Univ. of São Paulo.
B160
1119.4 Effects of the reversible acetylcholinesterase
inhibitor pyridostigmine on vascular reactivity of spontaneously
hypertensive rats.
R.M. Lataro, M.A.B. Silva, R.C.A. Tostes
and H.C. Salgado. Sch. of Med. of Ribeirão Preto, Univ. of São
Paulo.
B161
1119.5 The 5-HT
1A
receptor and sympathetic
neurotransmission to mesenteric blood vessels in salt-sensitive
hypertension.
J.D. Bomar and J.J. Galligan. Michigan State
Univ.
1120. NEURAL CONTROL OF VISCERAL AND
METABOLIC FUNCTION
Poster
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B162
1120.1 Further studies on the sensory motor
integration of gill lateral cilia in the bivalve mollusc Crassostrea
virginica.
P. Williams, P. Akande, E.J. Catapane and M.A.
Carroll. Medgar Evers Col., CUNY.
B163
1120.2 Glycemic control by the brain renin-angiotensin
system: role for peripheral AT2 receptors.
B.J. Weidemann,
N.K. Littlejohn, C.D. Sigmund and J.L. Grobe. Univ. of Iowa.
B164
1120.3 Shp2 signaling in Pomc neurons is important
for leptin’s actions on blood pressure, energy balance and
glucose homeostasis.
J.M. do Carmo, A.A. da Silva, P.O.
Sessums, S.H. Ebaad and J.E. Hall. Univ. of Mississippi Med.
Ctr.
B165
1120.4 Glucoprivation of hypothalamic neurons elicits
the counter-regulatory response in rats.
T.J. Verberne and
W.S. Korim. Univ. of Melbourne.
B166
1120.5 Systemic CCK increases brown adipose tissue
sympathetic nerve activity.
C.J. Madden. Oregon Hlth. & Sci.
Univ.
PHYSIOLOGY TUESDAY
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1121. BLOOD BRAIN BARRIER, BLOOD FLOW AND
METABOLISM
Poster
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B167
1121.1 In vitro modeling of inflammation-induced
blood-brain barrier dysfunction in sickle cell disease.
H.
Parfenova, T. Pestina, D. Persons and S. Basuroy. Univ. of
Tennessee, Memphis and St. Jude Children’s Res. Hosp.
B168
1121.2 Role of NOS in early-stage BBB disruption
following transient focal cerebral ischemia.
Z. Jiang, C. Li, D.M.
Arrick, S. Yang and H. Sun. LSU Hlth. Sci. Ctr.-Shreveport.
B169
1121.3 Cerebrovascular reactivity and implications
for understanding the pathophysiology of multiple sclerosis.
O. Pucci, A. Battisti-Charbonney, J. Fierstra, D.M. Mandell,
D. Mikulis, J. Poublanc, A. Crawley, J. Fisher and J. Duffin.
Univ. of Toronto and Univ. Hlth. Network, Toronto.
B170
1121.4 Cerebrovascular reactivity to carbon dioxide: a
theoretical examination.
O. Pucci, A. Battisti-Charbonney, J.
Fierstra, J. Poublanc, A. Crawley, D.M. Mandell, D. Mikulis, J.
Fisher and J. Duffin. Univ. of Toronto and Univ. Hlth. Network,
Toronto.
B171
1121.5 Role of fibrinogen in traumatic brain injury. N.
Muradashvili, R. Tyagi, R.L. Benton and D. Lominadze. Univ.
of Louisville.
B172
1121.6 Choroid plexus inorganic phosphate (Pi)
transport: stress-induced alteration of PiT-1 (Slc20A1)
localization.
J.L. Renfro, S.L. Parker and A. Bataille. Univ. of
Connecticut.
B173
1121.7 Aerobic training improves the integrity blood
brain barrier in spontaneously hypertensive rats.
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