This why a patient may die of multiple organ failure after traumatic hemorrhage, even when bleeding has been controlled and the patient resuscitated to normal vital signs and perfusion.
This why a patient may die of multiple organ failure after traumatic hemorrhage, even when bleeding has been controlled and the patient resuscitated to normal vital signs and perfusion.
The CNS is the prime trigger of the neuroendocrine response to shock, which maintains perfusion to the heart, kidney, and brain at the expense of other tissues.
Regional glucose uptake in the brain changes during shock.
Reflex activity and cortical electrical activity are both depressed during hypotension; these changes are reversible with mild hypoperfusion but become permanent with prolonged ischemia.