Anesthesiologists are involved: Anesthesiologists are involved

In a rat model of controlled hemorrhage, animals receiving LR solution showed an immediate increase in apoptosis in the liver and small intestine after resuscitation with LR.

Neither whole blood nor hypertonic saline increased the amount of apoptosis.

Hypertonic saline solutions, with or without the addition of polymerized dextran have been extensively studied in resuscitation from hemorrhagic shock.

• Hypertonic saline solutions, with or without the addition of polymerized dextran have been extensively studied in resuscitation from hemorrhagic shock.

• HS will draw fluid into the vascular space from the interstitium, HS a popular choice for fluid resuscitation

• Multiple studies of otherwise lethal hemorrhage in animals have demonstrated improved survival after resuscitation with HSD versus either normal saline solution or the components of HSD alone.

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