Bacterial Pathogenesis Pin Ling (凌 斌), Ph. D

Bacterial Pathogenesis

• Pin Ling (凌 斌), Ph.D.

• Department of Microbiology & Immunology, NCKU

• ext 5632

• [e-mail]

• References:

• 1. Murray, P. et al., Medical Microbiology (5th edition)

• 2. Samuel Baron, Medical Microbiology (4th edition)

Outline

Bacterial virulence factors

• Adhesins

• Pili (fimbriae)

• Nonfimbrial adhesins

• Invasion of host cells

• Tissue damage

• Growth byproducts

• Tissue-degrading enzymes

• Immunopathogenesis

• Toxins

• Exotoxins (cytolytic enzymes and A-B toxins); enterotoxins;

• superantigens;

• endotoxin and other cell wall components