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Helicase
-
motor proteins that separate two strands of hybridized DNA by moving in one direction along a
phosphodiester backbone
Replication forks
-
a multiprotein complex with DNA synthesis and helicase functions
DNA polymerase
-
enzymes that assemble nucleotides, the components of DNA, to form DNA molecules
Okazaki fragments
-
short DNA nucleotide sequences that are produced infrequently and then joined
collectively by the DNA ligase enzyme
Lagging strand
-
a single DNA strand that replicates in the 5′ - 3′ orientation when DNA is copied
DNA ligase
-
a particular kind of enzyme called a ligase (EC 6.5.1.1) that makes it easier to link DNA strands
together by facilitating the creation of a phosphodiester bond
3.2 VIDEO RESOURCES
Video #1:
The Structure of DNA:
https://youtu.be/o_-6JXLYS-k
Video #2:
DNA Replication:
https://youtu.be/9kp9wiYMQUU
Video #3:
Mechanisms of DNA damage and Repair:
https://youtu.be/sX6LncNjTFU
Unit III. GENETIC AND MOLECULAR BIOLOGY
Topics
3.1
Chromosomes and Meiosis
3.2
DNA as Genetic Information
3.3
Gene Expression
3.4
Genomics and Bioinformatics
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