Heparin Drip Calculation Reference (sample calculations for reference only!)



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Heparin Drip Calculation Reference 

(sample calculations for reference only!) 

 

Heparin Infusion Rate:  Total Units (in IV bag) = Units/hour  

                                          Total Volume (ml)         X (ml/hour) 

 

Your patient has a DVT is ordered for a heparin infusion to start at 18 units/kg/hour 

per the practitioner’s order.  His weight is 75kg.  The heparin infusion comes in a 

500ml bag with 25,000 units.  Calculate the starting rate of the infusion (ml/hour). 

 

Step 1:  Calculate the starting units per hour

.   

 

 

 

18 units X 75 kg = 1350 units/hour 

 

Step 2:  Calculate the starting rate of the Infusion (solve for X). 

 

 

         Heparin Infusion Rate:  25,000 units =  1350 units/hour  



                                                   500ml                 X (ml/hour) 

                                                

    

 

 



25,000 units (X ml/hr) = 675,000 

 

 

 

 

 

X ml/hr = 675,000 

 

 

 

 

 

     25,000 

 

 

   X 



27 

ml/hour 

 

Your patient’s PTT result is 55.  Per the Intravenous High Intensity Heparin 



Nomogram (for DVT/PE), the infusion dose should be increased by 2 units/kg/hour.  

Your patient is currently receiving an infusion based on 18/units/kg/hour.  What is the 

new rate for the infusion (note:  use the same initial weight to calculate the new rate). 

 

Step 1:  Calculate the new units per hour. 

 

 

 

 

18 units/kg/hour + 2 units/kg/hour = 20 units/kg/hour 

 

 

 

 

20units X 75 kg = 1500 units/hour 

 

Step 2:  Calculate the new rate of the infusion (solve for X). 

 

        Heparin Infusion Rate:  25,000 units = 1500 units/hour  



                                                  500ml                 X (ml/hour) 

                                                



    

 

 



25,000 units (X ml/hr) = 750,000 

 

 

 

 

 

X ml/hr = 750,000 

 

 

 

 

 

     25,000 

 

 

   X 



30 

ml/hour 



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