Msc in Diabetes a population approach Type 1 Diabetes

MSc in Diabetes A population approach

Type 1 Diabetes

• An auto immune disorder characterised by islet cell destruction

• Used to equate to insulin dependent diabetes mellitus (IDDM)

Diagnosis?

• Insulin dependent diabetes associated with auto antibodies e.g Islet Cell Antibodies (ICA) Insulin Autoantibodies (IAA) and Glutamic Acid Decarboxylase Antibodies (GADA) - 90% of white children with newly diagnosed diabetes have auto antibodies

• Some apparent type 1 diabetics have no demonstrable auto antibodies - 10%

• Epidemiological definition is IDDM developing in people before age of 35 years

Prevalence

Prevalence of Type 1 diabetes per 1000