Organizing co mmittee

 
 

---

Poster presentation 
222 
EVALUATION OF INSECTICIDAL POTENTIAL OF
1,3,4-OXADIAZOL-2-THIONS 
 
S.M. Turaeva, D.S. Ismailova, M.Sh. Ibragimova
 
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of the 
Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail] 
One of the dominant cotton pests in Uzbekistan is the cotton bollworm. Cotton 
bollworm, a widespread dangerous pest, is a polyphage that damages many fodder and 
technical plants. The main period of its harmfulness occurs during the development in 
the caterpillar phase, which develops inside the buds, flowers, ovaries, and fruit 
elements of cotton. It is reported that, on average, 88,000 tons of raw cotton crops are 
lost in the country annually due to the cotton bollworm [1]. 
A big problem in the use of chemicals is the development of pest resistance to them 
with constant use. The search for new types of insecticides with high activity, and low 
toxicity, and preventing the emergence of resistance and low residue content has 
become an urgent task for scientific researchers. 
Alkyl derivatives of 5-(
p
-aminophenyl)-1,3,4-oxadiazol-2-thione are reported to be 
highly toxic to sap-sucking pests such as 
Macrosiphum rosae
and 
Aphis pomi
[2]. 
In this regard, the study aims to assess the insecticidal potential of 1,3,4-oxadiazol-2-
the derivatives against the quarantine pest - cotton bollworm (
H. armigera
) in the 
natural conditions of the Tashkent region. 
To evaluate the biological effectiveness of 2-benzylthio-5-(4-aminophenyl)-1,3,4 
oxadiazole, laboratory experiments were carried out on the cotton bollworm caterpillar. 
According to the results of the studies, it was shown that the effectiveness of the 
studied substance at a dose of 0.1 mg/ml was 65.5% at a 24-hour incubation, and at a 
48-hour incubation - 69.0% against the caterpillar 
H. armigera
. Under the influence of 
the insecticide Bagira 20%, the efficiency reached up to 68.0% and 72.0%, respectively. 
Field trials showed that the biological effectiveness of 2-benzylthio-5-(4-
aminophenyl)-1,3,4 oxadiazole on day 7 was higher than 56.0% compared to control 
and 11.0% compared to insecticide BI -58. When spraying plants with the test 
substance, the efficiency for 14-21 days remained up to 58.0% -58.5%. 
Thus, the insecticidal potential of 1,3,4-oxadiazol-2-thione derivatives was 10.5% 
higher than that of the BI-58 insecticide and 18.5% higher than that of Entospilan. 
References 
1. Khodjaev Sh.T. Modern methods and means of integrated protection of plants 
from pests - Tashkent 2015, pp. 574. 
2. Turaeva S.M., Ismailova D.S., Muratova S.Kh., Allokulova S.B. Insecticidal 
activity of alkyl derivatives of 5-(p-Аminophenyl)-1,3,4-oxadiazole-2-thione. Siberian 
Journal of Life Sciences and Agriculture, 2021, vol. 13, no. 3, pp. 74-88. DOI: 
10.12731/2658-6649-2021-13-3-74-88