Organizing co mmittee

 

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Poster presentation 
305 
PROSPECTS OF USING Cistanche salsa
IN MEDICINE 
A.B. Bazarbaeva, G.B. Satimov, B. Nigmatullaev, A. Egamberdiev 
 
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of the 
Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail]
,
 
phone: [phone] 
Cistanche salsa
(C.A.Mey) Beck. – salt marsh cistanche, a perennial plant from the 
Orobanchaceae family. It looms in April and bears fruit in May-July. 
It is found mainly on sandy-clay and clay-saline soils and salt marshes in the desert 
zone, in the Bukhara, Navoi regions of Uzbekistan and Karakalpakstan. It parasitizes 
the roots of perennial plants from the genera 
Anabasis, Calligonum, Haloxylon 
and 
Salsola
. 
The main type of raw material is the underground mass of the plant – roots, the so-
called stolons, the harvesting of which begins after the fruiting of the plant, before 
retiring, when the content of biologically active substances is maximum. At this time, 
the plant is easily recognizable due to the presence of an aboveground part, which 
completely disappears after some cattle run and strong winds. Harvested stolons are 
cleaned from soil and other mineral impurities. The end of drying is determined by the 
fragility of the stolons. The raw materials are packed in bags of 15-20 kg or in bales of 
30 kg, stored in dry, ventilated rooms on racks protecting them from insect pests. 
We have studied the chemical composition of a sample of 
C.salsa
collected in the 
Bukhara region. The raw materials were crushed and extracted four times for 8 hours at 
room temperature with 70% aqueous alcohol, the resulting mass was mixed with KSK 
grade silica gel, fractionated on a chromatographic column and eluted sequentially with 
extraction gasoline, chloroform, ethyl acetate, isopropyl alcohol and a mixture of 
isopropanol : water (1:1). A compound was isolated from the fraction of isopropyl 
alcohol by chromatography on a column with silica gel and sephadex LH-20. Based on 
the study of spectral data of 1H and 13 C NMR, this compound was identified as 
betaine (trimethylglycine) 178-180
0
C. According to the literature, betaine has 
hepatoprotective properties and may be a source of a therapeutic drug. 
In the Central Asia the decoction is used for syphilis, water extracts show 
bactericidal activity, and it is recommended to use in the male and female genital areas, 
disorders of the musculoskeletal system, urinary system and circulatory disorders. 
Cistanche
is widely used in traditional medicine in China, as well as in Japan and 
Taiwan to create tonic drinks and remedies for the treatment of diseases of the urinary 
system, including chronic kidney failure. However, mainly, the plant 
Cistanche
is 
positioned as a remedy for the treatment of impotence and infertility. Many years of 
experience in using 
Cistanche
confirms the extraordinary properties of this plant. This is 
truly the "desert ginseng". At the same time, cistanche acts very gently, has no side 
effects and is suitable for long-term use. Indeed, numerous preclinical studies conducted 
in China and Japan have confirmed the antioxidant, anti-inflammatory, neuroprotective 
and immunostimulating properties of 
Cistanche 
extract. 
In the field research by O. Xojimatov (2018), it was found that the salt marsh 
Cistanche
parasitizes the host plant, and sometimes forming significant populations. In 
the average yield of raw materials of stolons of cistanche saline was 1.88 kg/ha, in air-
dry weight. Thus, 
Cistanche salsa
is a potential source of medicinal products and has 
good prospects for use in medicine.

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Poster presentation 
306