PHYTOCHEMICAL STUDIES OF BIOLOGICALLY ACTIVE SUBSTANCES OF THE AERIAL PART OF Daphne altaica A. Musagalikyzy 1 , Zh.Zh. Akzhigitova 1 , Ye. Shybyray 1 , J. Jenis 1 1 The Research Center for Medicinal Plants of Al-Farabi Kazakh National University*e- mail: janarjenis@kaznu.kz, arailym.musagalikyzy@icloud.com Daphne is a genus of 70 to 95 species of deciduous and evergreen shrubs in the
Thymelaeaceae family.
Daphne altaica is a rare endemic species to the north of Jungar
Basin of Xinjiang, Chine, Altai, Manrak and Tarbagatai Mountains of Kazakhstan, and
Altai region of Russia, as well as northwest Mongolia.
D. altaica is an insufficiently
explored rare endemic species from East Kazakhstan.
D. altaica is a medicinal herb
used in traditional Kazakh medicine for the treatment of numerous diseases, including
cancer of the digestive tract, tracheitis, common cold, sore throat, rheumatism and
snakebite. The plant is known for its anticancer properties. The Kazakh added the peel
of stem barks of
D. altaica to lamb broth and drank it against cancer
In this work, the quantative and quantative analysis of phytochemical constituens of
medicinal plant
Daphne altaica from Kazakhstan has been made for the first time. Total
bioactive components of
D. altaica such as organic acids (0.24%), flavonoids (0.223%),
coumarins (0.9848%) and together with moisture content (4.9%), total ash (4.27%), and
extractives content (11.36%), were determined. Eleven macro-micro elements from the
ash of the plant were identified, main contents of them were K (250.25mg/ml), Mg
(78.565mg/ml), Ca (71.88mg/ml) by using the method of multi-element atomic
emission spectral analysis. In addition, 20 amino acids and 8 fatty acids were studied
from the plant. Glutamine (2360), asparatic acid (2360) and alanine (625) predominated
among amino acids. Oleic (55.7) and linoleic (27.3) acids were contained in large
amounts compared to other fatty acids.