Poster presentation
42
STUDY OF THE ESSENTIAL OIL FRACTION FROM FERULA
PERSICA
E.G. Karimli
1,2
1
Azerbaijan Medical University, Baku, Azerbaijan
2
Institute of Botany, Ministry of Science and Education of the
Republic of Azerbaijan
Introduction.
The genus Ferula
belongs to the celery family, unites 130 species distributed in
Central Asia, Siberia, China (Xinjiang), Afghanistan, Iran and North Africa, 10 species
in the Caucasus and 8 species in Azerbaijan.
The chemical constituents from
F. persica
include volatile compounds, sesquiterpene
coumarins, sulfur-containing compounds, and sesquiterpene coumarin glycosides.
Osthole, sitosterol, L-chimgin, L-chimganin were obtained from
F. persica
growing in
Azerbaijan.
The roots of
Ferula
species contain large amounts of sesquiterpene
coumarin ethers
F. persica
contains biologically active sesquiterpene coumarins
including umbelliprenin, farnesiferols A and B. Umbelliprenin
has shown anti-
inflammatory, apoptotic and anti-pigmentation properties. Farnesiferols A and B
indicated reversal of multi-drug resistance and cytotoxic properties. Isolated
sesquiterpene coumarins and polysulfides from
F. persica
have cytotoxic, antibacterial,
antifungal.
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