Name of journal: World Journal of Transplantation esps manuscript no: 18452 Manuscript Type: Original Article Retrospective Study



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Research frontiers

By now, the first steps to develop new restorative therapy of SCI have been made, and the cell transplantation is the most obvious choice, although no universally acknowledged methods to restore spinal cord after the injury are observed. The methods of transplantation and the types of cells significantly vary; the evidence gathered is mostly limited by a one or two years follow up. Being involved into stem cell transplantation for SCI for about 25 years in research and in clinical practice we have accumulated substantial experience of achievements and failures in stem cell therapy. In the current work we describe the cell therapy that proved the safest and the most effective both in the short-term period and in long-term follow-up.



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