Develop an understanding of Midazolam and how it works
Develop an understanding of Midazolam and how it works
Develop an awareness of the Epilepsy emergency medication plan/ care plan
Demonstrate the correct procedure for the safe and effective administration of Midazolam
Demonstrate appropriate first aid for seizures and knowledge of when to call an ambulance
Used to prevent epileptic seizures developing into status epilepticus
First line treatment for prolonged seizures in the community (NICE 2012)
Prescribed on a named patient basis by Consultant Paediatrician, Consultant Neurologist, Consultant Psychiatrist or GP
Passes across the mucosal membranes and is absorbed into the blood stream
Passes across the mucosal membranes and is absorbed into the blood stream
Travels directly to the brain
Works at nerve cell junctions
Reduces brain excitability
Suppresses seizure activity
Acts within approximately 5 minutes
80% seizures stop within 10 minutes
Has a half life of 90 minutes
Almost completely cleared from body within 6 hours
Common side effects can include:
Common side effects can include:
Drowsiness
Disorientation
Agitation
Amnesia
Rare side effects can include:
Excessive sleepiness
Hypotension (low blood pressure)
Shallow breathing
Prolonged seizures
Prolonged seizures
When seizure lasts longer than normal for the person
Recurring seizures
When one seizure follows another without the person regaining consciousness
Seizure clusters
Recurring seizures over a time with person regaining consciousness in between
Can continue all day
Not a medical emergency but requires treatment
Depending on time between seizures Midazolam may be needed
The Epilepsy Emergency Medication plan should include:
Individual’s details
Usual seizure type requiring emergency medication
When to give emergency medication
Dose of medication
When to call 999
Consent and agreement by appropriate persons
Should be available for all staff to view and agreed by:
Should be available for all staff to view and agreed by:
Person with parental responsibility/carer
School teacher, respite/day centre manager etc.
Doctor/named nurse
Copy to be held parent/carer & named nurse
Copy must be kept with the emergency medication in a safe place, at room temperature.
Updated yearly or more frequently if required by the Named Nurse.
Only those staff trained in administration of rescue medication can give this to the individual. A list of these names must be kept by the manager/ principle.
Provide appropriate First Aid and Time the seizure.
Provide appropriate First Aid and Time the seizure.
Check the airway and clear any excess saliva away with a tissue (or nasal secretions if using intranasally)
Check the individual’s details with their emergency medication plan and product available.
Check Expiry date of midazolam solution
Check If using midazolam solution that it is clear and there are no white particles.
Remove cap from prefilled syringe. If using midazolam solution draw up prescribed amount.
Remove cap from prefilled syringe. If using midazolam solution draw up prescribed amount.
Insert the syringe into the space between the inside of the cheek and the teeth (Buccal cavity)
Slowly administer approx. half the liquid
Repeat the process in the opposite side
If the individual is lying on their side, insert all the midazolam into the lower side
Gently hold lips together for approximately 30 seconds
Record time midazolam was administered
Place in the recovery position as soon as seizure has stopped
Stay with the individual and provide reassurance
You think the individual needs urgent medical assistance
You think the individual needs urgent medical assistance
If the emergency medication fails to have effect, any breathing difficulties, recovery is slow or an injury is sustained.
Do not give a second dose of midazolam unless this has been indicated by a consultant and documented within the EEMP/ careplan.
Observe individual:
Observe individual:
Breathing & colour
Response to medication
Any injuries
Remain with individual & offer reassurance
Dispose of equipment safely & wash hands
Inform parent/carers as per plan
Record all details as per local policy
www.medicinesforchildren.org.uk
www.medicinesforchildren.org.uk
www.youngepilepsy.org.uk
www.epilepsyaction.org.uk
www.nice.org.uk The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. NICE guidelines [CG137]
www.medicinesforchildren.org.uk
www.medicinesforchildren.org.uk
www.youngepilepsy.org.uk
www.epilepsyaction.org.uk
www.nice.org.uk The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. NICE guidelines [CG137]