Obstruction/Congestion
tarix 07.03.2017 ölçüsü 478 b. #10727
Obstruction/Congestion Obstruction/Congestion Discharge/Purulence +/- Pain/Pressure +/-Hyposmia/Anosmia
Moderate-severe Moderate-severe . abnormal sleep . impairment of daily activities, sport, leisure . abnormal work and school . troublesome symptoms
History is often very suggestive History is often very suggestive
“no published prospective reports on the incidence of infective rhinosinusitis in populations with and without clearly defined allergic rhinosinusitis” EPOS 2007
Acute
Obstruction/Congestion Obstruction/Congestion OR Discharge/Purulence +/- Pain/Pressure +/-Hyposmia/Anosmia
Obstruction/Congestion Obstruction/Congestion Discharge/Purulence +/- Pain/Pressure +/-Hyposmia/Anosmia
54% Sensitivity and 46% Specificity in sinusitis (Kuhn, 1986) 54% Sensitivity and 46% Specificity in sinusitis (Kuhn, 1986) 75% of Plain X-Rays do not correlate with CT (McAlister and Lusk, 1989)
Aspergillosis Blastomycosis Aspergillosis Blastomycosis Rhinosporoidosis Cryptococcosis Phycomycosis Actinomycosis Candidiasis Hisptoplasmosis Sporotrichosis Mucormycosis
Non-invasive Non-invasive Fungal ball (mycetoma) Allergic fungal sinusitis (AFS) Invasive
Non-invasive Non-invasive Fungal ball (mycetoma) Allergic fungal sinusitis (AFS) Invasive Chronic invasive (indolent) fungal rhinosinusitis Acute invasive (fulminant) fungal rhinosinusitis
Type I Hypersensitivity Type I Hypersensitivity 80% of Patients Have Diffuse Polyps Thick Greenish Secretions with Fungal Hyphae
Sinus opacification Sinus opacification Expansion Bony erosion No tissue invasion
Acute
Dextrocardia Dextrocardia Rhinosinusitis Bronchiectasis Infertility
Infective Rhinosinusitis (Pseudomonas) Infective Rhinosinusitis (Pseudomonas) 37% of Patients Have Polyps Polyps in Children
Deviation of nasal septum Deviation of nasal septum Nasal polyps Hypertrophy of inferior turbinates Enlarged adenoids Foreign bodies Choanal atresia
Nasal obstruction Anosmia Postnasal drip
Gray-pink glistening structures Insensitive
36% of Patients Have Diffuse Polyps 36% of Patients Have Diffuse Polyps Bone Expansion High Recurrence Rate
Idiopathic Idiopathic NARES Occupational Hormonal Drugs Food Irritants Emotional
Nasal Hyperactivity to Nasal Hyperactivity to Cold air Temperature changes Tobacco, pollutants Perfumes, bleach
Neuronal markers in allergic rhinitis: expression and correlation with sensory testing. Neuronal markers in allergic rhinitis: expression and correlation with sensory testing. S O’Hanlon, P Facer, K Simpson, G Sandhu, HA Saleh , P Anand. Laryngoscope 2007 Sep;117(9):1519-27. Increased Nerve Fiber Expression of Sensory Sodium Channels Nav1.7, Nav1.8, and Nav1.9 in Rhinitis. SM Keh , P Facer, K Simpson, G Sandhu, HA Saleh , P Anand. Laryngoscope . 2008; 118(4):573-9. The role of neuronal mechanisms in allergic rhinitis. S O’Hanlon, SM Keh, HA Saleh Otorinolaringologia. 2008;58: 17-30.
Non-atopic Females > males Eosinophilia Steroid responsive
Symptoms improve in weekends and holidays Allergic Non-allergic
storage mites storage mites grain latex glues and guar gum rats, mice, guinea pigs basilis subtilis enzymes wood dust e.g. mahogany, western red cedar isotonic acid hydrazine/trimellitic anhydride
Pregnancy Pregnancy Puberty Premenstrual Hypothyroidism Acromegaly Old man’s drip
Local Local Systemic Antihypertensives Aspirin Contraceptive pill
Benzoates, salicylates Benzoates, salicylates Tetrazine Colourings
Pollution
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