1 friday, april 19 Biochemistry and Molecular Biology asbmb graduate and postdoctoral travel award keynote lecture special Session
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E. Glasgow and T. Weaver. Univ. of Wisconsin-La Crosse. C122
996.13 Contribution of an inner core hydrogen-bonding network to b-helix stability within the two-partner secretion exotoxin family. T.M. Weaver. Univ. Wisconsin-La Crosse. C123
996.14 Production and characterization of oxidation- resistant variants of the human ribonuclease inhibitor. A.W. Uebersohn and K.A. Dickson. Lawrence Univ., WI. C124
996.15 Analysis of the yeast de novo protein YNR034W-A. A. Shi and M. Cordes. Univ. of Arizona. C125
996.16 Mortal Kombat: modeling amyloid fibrils and health implications. M. Smaoui, F. Poitevin, M. Delarue, P. Koehl, H. Orland and J. Waldispuhl. Sch. of Computer Sci., McGill Univ., Inst. Pasteur, Univ. of California, Davis and CEA- Saclay, Gif-sur-Yvette, France.
333 T U E C126
996.17 ER stress-independent noncanonical UPR activation under phenformin treatment. L. Yang, H. Sha, Z. Xue and L. Qi. Cornell Univ. 997. MASS SPECTROSCOPY Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 1:05 pm -2:35 pm C127
997.1 A systematic study of the chemical stress response induced by bleach and vinegar in E. coli on viability and protein expression profiles using plating assays and matrix-assisted laser desorption ionization Biotyper™ system.
C128
997.2 Mass spectrometric immunoassay for insulin- like growth factor 1.
Fisher Scientific, Tempe, AZ and Cambridge, MA. C129
Muscle fiber typing by identification of the myosin heavy chain using LCMS.
C130
997.4 Development of LCMS method for monitoring the effects of meat feasting, fasting, and exercise on urinary 3MH levels. S. Fenstermacher, K. Cleary, E. Hayes and D. King. Taylor Univ. , IN. 998. CATALYTIC MECHANISMS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C131
998.1 Design and characterization of Thermotoga maritima glycerol dehydrogenase to reduce inactivation by dihydroxyacetone. P.G. Gross, J. Beauchamp and C. Vieille. Michigan State Univ. C132
The structure, regulation and activity of non- canonical inteins.
the Holy Cross. C133
Rational enzyme redesign for enhancing activity and selectivity of heterologous taxane oxidation in engineered
C134
998.4 Towards the nitric oxide reductase mechanism of flavodiiron proteins.
Texas at San Antonio. C135
The structural basis of the secondary function of PMM1 in the presence of IMP.
C136
998.6 Experimental and computational evidence that ribonuclease A alters the transition state for RNA 2’-O-transphosphorylation. M.E. Harris, H. Gu, K-Y. Wong, B. Radak, T. Dissanayake, D. Kellerman, S. Zhang, Q. Dai, M. Miyagi, V.E. Anderson, D. York and J. Piccirilli. Case Western Reserve Univ. Sch. of Med., Rutgers Univ., Piscataway and Univ. of Chicago. C137
998.7 Kinetic mechanism of human DNA ligase I. P.J. O’Brien. Univ. of Michigan Med. Sch. C138
998.8 Ligand binding and conformational change coupling in the HAD superfamily.
Harvard Univ. and Univ. of New Mexico. 999. MOLECULAR MOTORS - FORCE AND WORK AS PRODUCTS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C139
999.1 Plasticity of the kinesin-microtubule interaction is encoded by the motor domain beta-sheet.
C140
999.2 ATPase coupling in the processive RNA helicase NS3 from hepatitis C virus.
Inst. of Technol., Sanford-Burnham Med. Res. Inst., La Jolla and HHMI, New Haven. C141
999.3 Unraveling the architecture of the A1 complex of the Nanoarchaeum equitans A1A0 ATP synthase.
C142
999.4 A search for novel substrate activity in mutants of L-alanine dehydrogenase.
Vassar Col. and Hofstra Univ. C143
Electron transfer without metal:. how amino acid radicals (mis)behave.
t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C144
1000.1 Identification of the DNA binding surface on the SIRV capsid protein. H.E. Allgaier, R.E. Taurog, J.E. Johnson, C.E. Rohlman and B.R. Szymczyna. Albion Col., MI, The Scripps Res. Inst. and Western Michigan Univ. 1001. MOLECULAR MOTOR PROTEINS AND PUMPS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C145
1001.1 Myo1c, an unconventional motor that maintains glomerular filtration function. E. Arif, L. Mallik, Y.S. Rathore, B. Kumari, M. Ostap, F.N.U. Ashish, L.B. Holzman and D. Nihalani. Univ. of Pennsylvania and CSIR-Inst. of Microbial Technol., India. C146
b and delta subunits of ATP synthase in Escherichia coli? C.S. Gajadeera and J. Weber. Texas Tech Univ. and Texas Tech Univ. Hlth. Sci. Ctr. TUESDAY BIOCHEMISTRY 334 C147
1001.3 Structural model of a2-subunit N-terminus and its binding interface for cytohesin-2: implication for regulation of V-ATPase function.
Sch., State Res. Ctr. Virol. Biotech., Kolatsovo, Russia and Nanyang Technol. Univ., Singapore.
t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C148
1002.1 C1- tetrahydrofolate synthase contribution to 1C metabolism. D. Blemur , M. Field and P. Stover. Cornell Univ.
C149 1002.2 NMR studies of the N-terminal domains of E2 component of human pyruvate dehydrogenase complex. S. Kumaran, B. Birkaya, M. Patel and F. Jordan. Rutgers Univ. and Univ. at Buffalo SUNY. C150
the pyruvate dehydrogenase complex from Escherichia coli by hydrogen/deuterium exchange mass spectrometry.
C151
1002.4 Develop spatially-interactive multienzyme complex on selfassembled DNA nanostructures. J. Fu. Biodesign at Arizona State Univ. 1003. PROTEIN INTERACTIONS IN CATALYSIS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C152
1003.1 Thermodynamics and kinetics of the interactions of calmodulin with Orai. C-C. Wei, S. Shakya, D. Jensen and K. Bennett. Southern Illinois Univ. Edwardsville. 1004. REGULATION AND ALLOSTERISM Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C153
1004.1 The allosteric regulation of phenylalanine hydroxylase provides a foundation for new PKU therapies. E.K. Jaffe, L. Stith, S.H. Lawrence, M. Andrake and R.L. Dunbrack. Fox Chase Cancer Ctr., Temple Hlth. C154
1004.2 Probing the effects of cofactor and substrate on conformation and flexibility of human pGDH. C. Roach and E. Bell. Univ. of Richmond. C155
1004.3 Regulation of assembly of bipolar myosin II filaments. A. Kandel, R. Frei and K. Prehoda. Univ. of Florida and Univ. of Oregon. C156
amaurosis disrupt retinal guanylate cyclase interaction with rhodopsin in vitro; involvement in phototransduction.
Univ. Nevda Col. of Osteo. Med. C157
variant of PLA2g6, and regulation of its catalytic activity by Ca 2+
2+ influx factor. S. Korolev, P. Csutora, K. Peter, O. Koroleva, P. Subramanya, K. Malley and V.M. Bolotina. Saint Louis Univ. Sch. of Med. and Boston Univ. Sch. of Med.
C158 1004.6 Structure-function studies of the ADPglucose pyrophosphorylase from Thermodesulfovibrio yellowstonii. M. Susoeff, E. Yik, S. Kaur, G. Dua, M. Badal, A. Orry and C.R. Meyer. California State Univ., Fullerton and Molsoft LLC, San Diego.
C159 1004.7 Use of recombinent casein peptides as inhibitors of spPEP. S. Basak and B. Clack. Stephen F. Austin State Univ. C160
secondary activator of the Escherichia coli ADP-glucose pyrophosphorylase.
Argentina. C161
operator. J.D. Williams, D. Jackson and R. Villafane. Alabama State Univ. and Huntingdon Col. C162
apparent affinity and allosteric activation of Escherichia coli ADP-glucose pyrophosphorylase.
C163
1004.11 Probing the role of E304 in the allosteric site of ADPglucose pyrophosphorylase from Agrobacterium tumefaciens. S. Bor, H. Karzai, K. Chastain, A. Orry and C.R. Meyer. California State Univ., Fullerton and Molsoft LLC, San Diego.
C164 1004.12 Small crosslink may stabilize P22 tail protein at N-terminus. C. Palmer, S. Johnson, D. Dean and R. Villafane. Alabama State Univ. and Huntingdon Col. 1005. ROLE OF DYNAMICS IN ENZYME CATALYSIS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C165
1005.1 Structural analysis of an intein from an extreme thermophile. J.E. Williams, J.N. Reitter and K.V. Mills. Col. of the Holy Cross. C166
stabilizing the structure of a thermophilic intein. K.M. Colelli, J.M. Pusztay, J.N. Reitter and K.V. Mills. Col. of the Holy Cross.
BIOCHEMISTRY TUESDAY 335 T U E 1006. BIOPHYSICAL METHODS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C167
1006.1 Measurement of urinary catecholamines for mice.
E.A. Smith, A.L. Schwartz, T.L. Garrett and J.B. Lucot. Wright State Univ. C168
in macromolecular assemblies. K.C. Anthony, C. You, J. Piehler and D. Pomeranz Krummel. Brandeis Univ. and Univ. of Osnabrück, Germany. C169
carbon nanoparticles in sock fabric. Y.G. Gete and R. Walker. Metropolitan State Univ. of Denver. C170
butyrate induced differentiation in colon cancer cells in a time- dependent manner.
C171
1006.5 Neuronal networks on the nano alumina templates. A. Islam. Northeastern Univ. 1007. CYTOCHROME P450 Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 12:25 pm -1:55 pm C172
1007.1 Metoclopramide is a substrate but not an inactivator of CYP2D6. A.K. Bolles, E.D. Briggs, M.R. Livezey, L.D. Nagy and L.L. Furge. Kalamazoo Col. C173
1007.2 CYP2D6 is the major metabolizing enzyme of metoclopramide. E.D. Briggs, A.K. Bolles, M.R. Livezey and L.L. Furge. Kalamazoo Col. C174
1007.3 Interaction of mechanism-based inactivators with modified CYP2D6. M.R. Livezey, M.J. Hicks and L.L. Furge. Kalamazoo Col. C175
1007.4 Covalent modification of CYP2D6 following inactivation by SCH66712. M.J. Hicks, M.R. Livezey and L.L. Furge. Kalamazoo Col. C176
1007.5 Regio- and stereo-selective oxidation of fluorinated substrates by recombinant cytochrome P450 BM3 variants.
Taipei, Natl. Cheng Kung Univ. and Natl. Taiwan Univ. of Sci. and Technol., Taiwan. C177
1007.6 Regulation of phase I and phase II enzyme gene expressions and their activities by caffeic acid, major compound of Perilla frutescens.
C178
1007.7 Metabolism of cyclophosphamide by CYP2B6 and associated polymorphisms. J.M. Abbott, D. Calinski and P. Hollenberg. Kalamazoo Col. and Univ. of Michigan Med. Sch.
C179 1007.8 Cytochrome P450 autophagy: activation by acute hepatic heme depletion. Y. Liu and M.A. Correia. UCSF. 1008. METABOLIC NETWORKS Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 1:05 pm -2:35 pm C180
1008.1 Metabolic responses of the aerobic anoxygenic phototrophic bacterium Roseobacter denitrificans during photoheterotrophic and heterotrophic growth.
Clark Univ., MA. 1009. METABOLIC REGULATION Poster t ue . 7:30 am —B oston C onvention & e xhiBition C enter
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a-B Presentation time: 1:05 pm -2:35 pm C181
1009.1 Sickle hemoglobin disturbs normal coupling between erythrocyte O 2 content, glycolysis and antioxidant capacity. S.C. Rogers, J. Ross, A. d’Avignon, L. Gibbons, M. Hassan, D. McLaughlin, S. Griffin, T. Neumayr, M. DeBaun, M. DeBaun and A. Doctor. Washington Univ. in St. Louis and Vanderbilt Univ. C182
mouse model. K. Mukherjee, L.L. Ballantyne, A. Sin, T. St. Amand and C.D. Funk. Queen’s Univ., Canada. C183
1009.3 Hyperargininemia in an inducible arginase-1- deficient mouse model. A. Sin, L.L. Ballantyne, K. Mukherjee, T. St. Amand, C. McCracken, V. Levandovskiy, A. Schulze and C.D. Funk. Queen’s Univ., Canada and The Hosp. for Sick Children, Toronto. C184
expression. J.M. Boylan, D.W. Lamming, N. Neretti, J. Ferreira, D.M. Sabatini and P.A. Gruppuso. Brown Univ. and Whitehead Inst. for Biomed. Res., Cambridge, MA. C185
of intracellular ferritin in mosquito cells. Z.R. Conley, D. Geiser and J. Winzerling. Univ. of Arizona. C186
1009.6 Structure of the carnitine palmitoyltransferase- 1A gene in rats, mice and humans. G.A. Cook and E.A. Park. Univ. of Hlth. Sci. Ctr. Yüklə 5,12 Mb. Dostları ilə paylaş:
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