1 friday, april 19 Biochemistry and Molecular Biology asbmb graduate and postdoctoral travel award keynote lecture special Session
Yüklə 5,12 Mb. Pdf görüntüsü
|
|
Y-Q. Cao and M.R. Bruchas. Washington Univ. Sch. of Med. W68
1173.5 Phosphorylation and internalization of short splicing variant of the omega 3 fatty acid sensor,GPR120. O.B. Sanchez-Reyes, J.A. Castillo-Badillo, M.T. Romero-Avila, Y. Takei, A. Hirasawa, G. Tsujimoto, R. Villalobos-Molina and J.A. García-Sáinz. UNAM, Mexico City, Grad. Sch. of Pharmaceut. Sci. , Kyoto Univ. and Col. Fac.-Iztacala, UNAM, Tlalnepantla. W69
1173.6 Visualizing trafficking of the adenosine-A 3
receptor using a fluorescent agonist: a tool for delineating intracellular signaling. S. Briddon, L. Stoddart, A. Vernall, B. Kellam and S. Hill. Univ. of Nottingham, U.K. W70
1173.7 ADAM17 regulates sphingosine 1 phosphate receptor 1 cell surface expression and downstream signaling. B.V. Desai, A. Ludwig, A.B. Malik and D. Mehta. Univ. of Illinois at Chicago and RWTH Aachen Univ., Germany. PHARMACOLOGY WEDNESDAY 415 W E D W71
1173.8 PDZ ligand-dependent phosphorylation of Ser
336 in the C-terminal tail of the P2Y 1 receptor blocks agonist- promoted internalization in HEK293 cells. R.A. Nicholas, K. Harden and A-D. Qi. Univ. of North Carolina at Chapel Hill and Vanderbilt Univ. W72
activity in the regulation of neuromedin U receptor re- sensitization and ERK signaling.
Arabia and Univ. of Leicester, U.K. W73
b1-adrenergic receptor resensitization and recycling.
Tennessee, Memphis. W74
regulates CB1 receptor trafficking. L.C. Blume, G.D. Dalton, D.E. Selley and A.C. Howlett. Wake Forest Baptist Hlth. and Virginia Commonwealth Univ. W75
pharmacological chaperones to rescue the plasma membrane expression of a mutant muscarinic M 1 receptor. G.W. Sawyer and C. Shults. Oklahoma State Univ. W76
1173.13 Mouse Flower-like, a membrane protein involved in endocytosis? S. Mannebach-Götz, K. Frohnweiler, U. Wissenbach and V. Flockerzi. Univ. of Saarland, Germany. 1174. RECEPTOR NEUROPHARMACOLOGY Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W77
1174.1 A new potent and specific 5-HT2C receptor agonist with preclinical anti-psychotic and anti-obesity properties.
W78
1174.2 Selective allosteric modulation of the 5-HT3A receptor by halogenated indole derivates. N. Barnes, A. Chiarenza, S. Gambassi, A. Powell and G. Grafton. Univ. of Birmingham Med. Sch., U.K. W79
receptors with selectivity for the NR1A/2A subtype. K. Sugunan, S. Downing, T.T. Gibbs and D.H. Farb. Boston Univ. Sch. of Med.
W80 1174.4 Affinity and selectivity of luzindole analogs in mouse and human MT1 and MT2 melatonin receptors transiently expressed in mammalian cells.
Buffalo, SUNY. W81
on the sigma1 receptor. J.M. Schrock, M.M. Islam, F.J. Kim, S.G. Grinnell and G.W. Pasternak. Mem. Sloan Kettering and Drexel Col. of Med. W82
3 H] D-aspartate release from isolated bovine retina by 5-epi-5-F 3t - isoprostane: role of prostanoid receptors. C.A. Opere, J. Jamil, A. Salvi, P. Bankhele, A. Flowers, N. Floyd, T. Durand, J-M. Galano, A. Guy, C. Oger, Y.F. Njie-Mbye, M. Kulkarni and S.E. Ohia. Creighton Univ., Biomolec. Inst. Max Mousseron, Montpellier and Texas Southern Univ. 1175. CELLULAR NEUROPHARMACOLOGY Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W83
1175.1 Characterization of Src and EGFR protein expression in chronic morphine treated SH-SY5Y cells. K. Randell, R. Prenus and C.B. Goodman. Florida A&M Univ. W84
1175.2 SN79, a sigma receptor ligand, mitigates methamphetamine-induced astrocyte and microglial activation. M.J. Robson, R.C. Turner, Z.J. Naser, J.D. Huber, C.R. McCurdy and R.R. Matsumoto. West Virginia Univ. and Univ. of Mississippi. W85
cells by altering the expression cell cycle regulatory protein. J. Triplett, R. Badisa and C.B. Goodman. Florida A&M Univ. W86
1175.4 Opioid-immune crosstalk: role of microRNA regulation following opioid and cytokine treatment in normal human astrocytes.
W87
1175.5 The role of a- and b-estrogen receptors on neurite outgrowth in Neuro-2A cells.
W88
1175.6 Prenatal cocaine exposure inhibits neurite outgrowth through rage pathway and activates altered expression of pro-addictive cytokines in primary neuronal and glial cell cultures. M.L. Johnson, T. Womble and T.L. Jackson. Florida A&M Univ. W89
idebenone and ferulic acid, in MPTP/MPP + intoxicated PC12 cells as a model of Parkinson’s disease. S. Gupta and K. Benzeroual. Long Island Univ. W90
1175.8 Neuroprotective effects of fisetin and diosmetin, alone and in combination, on lipopolysaccharide-induced neuronal cells.
Univ.
W91 1175.9 The influence of methadone on Toll-like receptor 4 and human mu opioid receptor expression. S. Dodson, S. Das, R. Davis and C.W. Stevens. Oklahoma State Univ. Ctr. for Hlth. Sci. 1176. SYSTEMS NEUROPHARMACOLOGY Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W92
1176.1 Feedback control of upstream 5-hydroxytryptamine (5-HT) in the dorsal raphe nucleus by downstream 5-HT2A and AMPA receptors in the prefrontal cortex.
Z. Zhou, P.G. Chan, J. Sun and J.A. Uchizono. Univ. of Pacific and Western Univ. of Hlth. Sci. W93
dorsal hippocampus in the hypophagic effect caused by fluoxetine in rats.
W94
1176.3 Uridine enhances in vivo acetylcholine release in rat striatum. M. Cansev, E. Orenlili Yaylagul, F. Orhan and M. Turkyilmaz. Uludag Univ., Turkey. WEDNESDAY PHARMACOLOGY 416 W95
1176.4 Effects of parabolic flight on serotonin- related gene expression in the mouse brain. M. Yoshioka, T. Yamaguchi, H. Ohta and T. Ochiai. Hokkaido Univ., Nagasaki Intl. Univ., Torii Pharmaceut. Co. Ltd. and Mitsubishi Heavy Industry, Kobe, Japan. W96
1176.5 Presence of octopamine and octopamine receptors in ganglia and tissues of Crassostrea virginica. C. Welsh, F. Bess, E.J. Catapane and M.A. Carroll. Medgar Evers Col., CUNY. W97
neuromedin B receptors in the neurotransmission of itch in the spinal cord of mice.
Michigan Med. Sch. 1177. NEURODEGENERATION/NEUROREGENERATION Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W98
1177.1 Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease.
W99
1177.2 AAV2/1-mediated gene delivery of CD200 into the hippocampus enhances neurogenesis and amyloid clearance in the APP mouse.
and Univ. of Nebraska Med. Ctr. W100
expression, microglial activation, and impaired spatial memory. S.A. Austin, A.V. Santhanam, D.J. Hinton, D-S. Choi and Z.S. Katusic. Mayo Clin. W101
1177.4 The science of repurposing drugs in Alzheimer’s disease therapeutics: the tale of rexinoid receptor ligand IRX4204.
W102
1177.5 Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer’s disease.
W103
1177.6 Repurposing anti-hypertensive drugs for Alzheimer’s disease. G.M. Pasinetti. Mount Sinai Sch. of Med. W104
1177.7 Chocolate may attenuate cognitive deterioration in Alzheimer’s disease through prevention of gene expression related to depressive disorder.
Sch. of Med. W105
neuroprotection in a murine model of traumatic brain injury. I. Paterniti, R. Crupi, M. Campolo, R. Di Paola, S. Cuzzocrea and E. Esposito. Univ. of Messina, Italy. W106
1177.9 Dopamine transporter affects cellular localization of a-synuclein. B. Butler, S. Goodwin, M. Zarindast,
Florida, Meharry Med. Col. and Tehran Univ. of Med. Sci. W107
steps in preclinical development. B.L. Waszczak, L. Wachtman, G.C. Newsome, A. Aly, N. Silva, S. Westmoreland, J. Rowlett and M.M. Migliore. Northeastern Univ., Harvard Med. Sch., Southborough and Massachusetts Col. of Pharm. and Hlth. Sci. W108
a 1A adrenergic receptor influences on progenitor cell fate in the adult hippocampus. K. Collette, A. Nielsen, D. Perez and V. Doze. Univ. of North Dakota and Cleveland Clin. Fndn. W109
exposure on neurogenesis in mouse hippocampus. C. Nguyen, T. Carter, C. Carothers, A. Hanley and B.B. Pond. Bill Gatton Col. of Pharm., East Tennessee State Univ. W110
derived neurotrophic factor production and neurogenesis in the hippocampus following ischemic brain injury.
W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W111
1178.1 Hydrogen sulfide increases aqueous humor outflow in porcine trabecular meshwork. J.D. Robinson, Y.F. Njie-Mbye, A. Okpobiri, M. Chitnis, C.A. Opere and S.E. Ohia. Texas Southern Univ. and Creighton Univ. W112
1178.2 Effect of hydrogen sulfide on isolated bovine ocular smooth muscle. A.C. Okpobiri, Y.F. Njie-Mbye, J. Robinson, M. Chitnis, C. Opere and S. Ohia. Univ. of Texas at Austin, Texas Southern Univ. and Creighton Univ. W113
of Ca
2+ , ATP and cytokines from RPE cells. C.H. Mitchell, S. Guha, J.M. Beckel and A.M. Laties. Univ. of Pennsylvania. W114
1178.4 Prenatal hypoxia causes long-term retina dysfunction in rats. S.L. Bourque, S. Kuny, Y. Sauve and S.T. Davidge. Univ. of Alberta. W115
1178.5 Role of the Krebs cycle metabolites in retinal angiogenesis. F. Duhamel, K. Zaniolo, H. Tahiri and S. Chemtob. Univ. of Montreal and CHU Ste-Justine Res. Ctr., Montreal. W116
axon retraction induced by retinal detachment. W. Wang and E. Townes-Anderson. UMDNJ, Newark. 1179. GENERAL TOXICOLOGY Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W117
1179.1 Safety evaluation of a second generation enzyme replacement therapy. A.L. D’Angona, P. Finn, J. Murray, A. McVie-Wylie and L. Andrews. Genzyme, Framingham, MA. W118
prostate carcinoma DU145 cells. V. Idikuda, M. Lai, J. Pfau, A. Bhushan, S. Leung and J. Lai. Idaho State Univ. W119
1179.3 Chelating agents reverse neurotoxic effects of manganese on dopaminergic innervation of gill of the bivalve mollusc Crassostrea virginica.
W120
1179.4 Mrp1 protects against doxorubicin-induced cardiotoxicity in vitro. W. Zhang, D. Coy, J. Deng and M. Vore. Univ. of Kentucky. PHARMACOLOGY WEDNESDAY 417 W E D W121
1179.5 Cleavage of ROCK II: as a common phenomenon in cell death. A. Ozdemir, B. Ibisoglu, Y.D. Simay, B. Mitrovic Yaren and M. Ark. Gazi Univ. Fac. of Pharm., Turkey. W122
insights into Parkinson’s disease therapy. E.M.G. Allen and J.J. Mieyal. Case Western Reserve Univ. and Louis B. Stokes VA Med. Res. Ctr. W123
lysine deacetylation, with no change in sirtuin expression, in the heart and liver of fasted animals.
Wingate Univ. Sch. of Pharm., NC. 1180. GENE REGULATION AND EXPRESSION Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W124
1180.1 PKC phosphorylation of Med25 is critical for mediator assembly: implications for HNF4 a signaling in drug metabolism. S-Y. Zhang, S. Surapureddi and J.A. Goldstein. NIEHS, NIH, Research Triangle Park. W125
tamoxifen, pterostilbene, raloxifene and clomiphene fail to stimulate the hepatic expression of estrogen responsive genes encoding the avian apolipoprotein II and vitellogenin. V.D. Bhatt and W.N. Ratna. Arnold & Marie Schwartz Col. of Pharm., Long Island Univ. W126
CYP2A13/2B6/2F1-transgenic mouse model. Z. Liu, L. Li, H. Wu and X. Ding. New York State Dept. of Hlth. and SUNY at Albany.
W127 1180.4 Regulation of MOR-1A, an intron-retention splice variant of the mu opioid receptor (OPRM1) gene, by miR-107.
Mem. Sloan-Kettering Cancer Ctr. W128
proteins that mediate alternative polyadenylation in cardiac myocytes.
of Cincinnati and Xavier Univ., OH. W129
expression and drug metabolism. Q-Y. Zhang, P. Zhang, K. Jia, C. Fang, X. Zhou and X. Ding. NYS Dept. of Hlth., Albany and SUNY at Albany. W130
on liver metabolic gene expression. V.E. Wotring. NASA, Houston.
W131 1180.8 A novel redox-based epigenetic signaling mechanism for opioids. M. Trivedi, N. Hodgson, J. Shah and R. Deth. Northeastern Univ. W132
1180.9 A major compound isolated from Undaria pinnatifida downregulates CYP3A4 and MDR1 expression by antagonizes pregnane X receptor activation. Y.P. Lim, C.L. Liu and M.L. Hu. China Med. Univ. and Natl. Chung Hsing Univ., Taiwan.
W133 1180.10 Alternative polyadenylation mediated shortening of the Hsp70.3 3’UTR increases polyribosome loading of the mRNA transcript.
W134
1180.11 Transcription factor BCL11B enforces asymmetric enamel-secreting cell development in the mouse incisor by bidirectional regulation of gene expression.
State Univ. 1181. STEM CELLS AND REGENERATIVE MEDICINE Poster W eD . 7:30 am —B oston C onvention & e xhiBition C enter
, e xhiBit h alls
a-B Presentation time: 12:30 pm -2:30 pm W135
1181.1 MALT lymphoma stem cell and its niche in Helicobacter heilmannii-infected mice stomach. M. Nakamura, H. Matsui, T. Takahashi, K. Tsuchimoto and S. Takahashi. Kitasato Univ. and Kyorin Univ., Tokyo and Mitaka, Japan. W136
Yüklə 5,12 Mb. Dostları ilə paylaş:
|