1 friday, april 19 Biochemistry and Molecular Biology asbmb graduate and postdoctoral travel award keynote lecture special Session

335.1 

Glycan-dependent control of myelopoiesis. 

J. 

Lowe, D. Yao, B. Petryniak, J. Shim, P. Stanley and L. Zhou. 

Genentech Inc., Case Western Reserve Univ. and Albert 

Einstein Col. of Med.

4:15   

TDX, a galectin-1 and galectin-3- specific 

inhibitor, mitigates VEGF-A-induced angiogenesis. 

W-S. Chen, 

H. Leffler, U.J. Nilsson and N. Panjwani. Tufts Univ. and Univ. 

of Lund, Sweden. 

(828.1)

4:30 

335.2 

Post-transcriptional regulation of lunatic 

fringe provides a critical mechanism to control Notch pathway 

signaling during somitogenesis. 

S.E. Cole, M.F. Riley, D.R. 

Williams and E.T. Shifley. The Ohio State Univ.

4:55 

 

A defined glycosaminoglycan-binding surface 

facilitates endoderm differentiation of human embryonic stem 

cells. 

B.A. Hernandez, P.J. Wrighton, J.R. Klim and L.L. 

Kiessling. Univ. of Wisconsin-Madison. (594.5)

5:10   

Truncated O-glycans enhance tumorigenicity 

of pancreatic tumors. 

P. Radhakrishnan, J.A. Grunkemeyer, 

H. Clausen and M.A. Hollingsworth. Univ. of Nebraska Med. 

Ctr. and Panum Inst., Univ. of Copenhagen. 

(592.7)

5:25 

335.3 

Site-specific analysis of O-fucose and 

O-glucose glycans on Notch. 

R.S. Haltiwanger, N. Rana, S. 

Kakuda, G-R. Hwang, E. Tan and H. Takeuchi. Stony Brook 

Univ.

5:50 

 

Discussion and closing remarks.

336.  LIPID TRAFFICKING AND SORTING

Symposium

(Supported by an educational grant from Avanti Polar 

Lipids, Inc.)

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This symposium features the Walter A. Shaw Young 

Investigator in Lipids Award lecture.

3:45 

 

Chair’s introduction.

3:50 

 

Introductory remarks. 

P. Espenshade.

3:55 

 

Cell biology of neutral lipid storage. 

T. Walther. 

Yale Med. Sch. 

(333.1)

4:25 

336.1 

The role of lipid transfer proteins in membrane 

trafficking and signal transduction. 

S. Lev, S. Kim, A. Kedan, 

M. Selitrennik and O. Keinan. Weizmann Inst. of Sci., Israel.

TUESDAY BIOCHEMISTRY

90

4:50 

336.2 

Molecular dynamics of endomembrane 

structure and function. 

J.A. Lippincott-Schwartz. NICHD, 

NIH.

5:15  

a-TTP-expressing astrocytes regulate 

a-tocopherol homeostasis in the CNS. L.M. Ulatowski, J. 

Atkinson and D. Manor. Case Western Reserve Univ. and 

Brock Univ., Canada. 

(814.2)

5:30 

336.3 

Endocytic membrane traffic and cell signaling. 

M. von Zastrow, P. Temkin, A. Henry and R. Irannejad. UCSF 

and Stanford Univ.

5:55 

 

Discussion and closing remarks.

337.  COOL CATALYSIS AND RADICALLY NEW 

REACTION MECHANISMS

Symposium

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3:45 

 

Chair’s introduction.

3:50 

337.1 

Novel enzymatic transformations in secondary 

metabolism and tRNA modification. 

V. Bandarian. Univ. of 

Arizona.

4:15 

 

Completing our understanding of tetracycline 

biosynthesis: the enzymatic basis of the F420-dependent final 

reduction step. 

Y. Tang and P. Wang. UCLA. (788.1)

4:30 

337.2 

Investigating roles of reader domains in 

regulating activity of jumonji histone demethylases. 

D.G. 

Fujimori. UCSF.

4:55   

Nitrile-synthetic enzyme involved in the 

formation of a carbon-nitrogen triple bond. 

M. Kobayashi, J. 

Nomura and Y. Hashimoto. Grad. Sch. of Life & Envrn. Sci., 

Univ. of Tsukuba, Japan. 

(788.2)

5:10 

 

Kinetic mechanism of human DNA ligase I. 

P.J. 

O’Brien. Univ. of Michigan Med. Sch. (998.7)

5:25 

337.3 

Radicals: your life is in their hands. 

J. Stubbe. 

MIT.

5:50 

 

Discussion and closing remarks.

338.  G-PROTEINS IN CELLULAR REGULATION

Symposium

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3:45 

 

Chair’s introduction.

3:50 

338.1 

RhoA and Rap1 mediate GPCR crosstalk to 

integrins and cell growth. 

J.H. Brown, O. Yu, D. Stupack and J. 

Sayyah. UCSD Sch. of Med.

4:15 

 

Structural basis of human cannabinoid CB1 G 

protein-coupled receptor activation. 

C.E. Scott, R. Abrol, K.H. 

Ahn, Y. Huang, D.A. Kendall and W.A. Goddard III. Caltech 

and Univ. of Connecticut. 

(831.4)

4:30 

338.2 

Lysophospholipid GPCRs in medical 

therapeutics and disease mechanisms. 

J. Chun. The Scripps 

Res. Inst.

4:55 

 

Thyroid hormone induction of adult stem cell 

formation during postembryonic development: an essential role 

of sonic hedgehog signaling mediated cell-cell interaction. 

Y-B. 

Shi. NICHD, NIH. (831.1)

5:10 

 

Insight into the involvement of G

bg in nuclear 

G protein-coupled receptor signaling. 

B.D. Spiegelberg, A. 

Cymerman, L. Ripley and B. Enalls. Rider Univ., NJ. (831.11)

5:25 

338.3 

Novel G protein- and GPCR-regulated 

oncogenic signaling circuitries. 

J.S. Gutkind. NIDCR, NIH.

5:50 

 

Discussion and closing remarks.

339.  ASBMB WOMEN SCIENTISTS’ NETWORKING 

EVENT/RECEPTION

Special Event

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Each year, ASBMB sponsors a session where women 

scientists reflect on some aspect of their careers or general issues 

surrounding women’s participation in science. This year, we will 

explore the challenges and transitions that women experience in 

the different stages of their scientific careers (early, mid, and late 

career).

Are you Tweeting about  

EB 2013?

To Tweet use #EB2013

Be sure to follow EB on Facebook  

  

and Twitter 

.

POSTER PRESENTERS:  

UPLOAD YOUR POSTER

Where: E-Poster Counter, Sun. – Tue. Hall A; 

Wed. Hall C

Deadline: Tue., April 23, 5:00 

pm

 

Wed., April 24, 3:00 

pm

Uploaded posters will be available online to 

all registered attendees following the meeting 

at www. experimentalbiology.org

BIOCHEMISTRY TUESDAY

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Nutrition

342.  LIPIDOMICS TECHNOLOGIES AT THE 

BEGINNING OF THE NEXT DECADE

Workshop

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Biochemical, Molecular and Genetic Mechanisms

8:00 

Our perception of the lipidome after the first decade of 

lipidomics. 

E. A. Dennis. UCSD.

8:30 

Lipid analysis by multiple “omic” mass spectrometry 

platforms. 

J. McDonald. Univ. of Texas Southwestern 

Med. Ctr.

9:00 

Lipidomics databases and other online tools. 

E. Fahy. 

UCSD.

9:30 

Lipidomics comes of age in nutrition and other 

translational sciences. 

A. H. Merrill. Georgia Tech.

343.  ASSESSMENT OF CHILD AND ADOLESCENT 

NUTRITIONAL STATUS, GROWTH AND OBESITY

Minisymposium

(Sponsored by: Nutritional Epidemiology RIS)

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8:00 

343.1 

A prospective study of global DNA methylation 

and development of adiposity in Colombian schoolchildren. 

W. Perng, M. Mora-Plazas, L.S. Rozek, C. Marin, A. Baylin 

and E. Villamor. Univ. of Michigan Sch. of Publ. Hlth. and Res. 

Fndn. in Nutr. Hlth., FINUSAD, Bogota.

8:15 

343.2 

Tracking of serum lipid levels and 

anthropometric measures from 3-4y to 7-8y. 

M.R. Vitolo and 

P.D.B. Campagnolo. Fed. Univ. of Hlth. Sci. of Porto Alegre 

and Univ. do Vale do Rio dos Sinos, Brazil.

8:30 

343.3 

Vitamin C intake, lead exposure, and oxidative 

stress in Uruguayan school children. 

A. Roy, E. Queirolo, F. 

Peregalli, N. Mañay and K. Kordas. Penn State and Catholic 

Univ. and Univ. of Republic, Montevideo, Uruguay.

8:45 

343.4 

Three-year incidence of obesity among U.S. 

children aged 0-23 months living in low-income families. 

L. 

Pan, A. May, H. Wethington, K. Dalenius and L. Grummer-

Strawn. Ctrs. for Dis. Control and Prevent.

9:00 

343.5 

Beverage consumption among young children 

of different race/ethnic backgrounds from the National Health 

and Nutrition Examination Survey. 

E.E. Quann, N. Auestad 

and V.L. Fulgoni III. Natl. Dairy Council, Rosemont, IL and 

Nutr. Impact LLC, Battle Creek, MI.

9:15 

343.6 

The effect of eating frequency on total energy 

intake, BMI z-score and diet quality in children and adolescents. 

E.W. Evans, P. Jacques, G.E. Dallal, J. Sacheck and A. Must. 

Friedman Sch. of Nutr. Sci. and Policy, USDA and Sch. of Med., 

Tufts Univ.

340.  PUBLIC-PRIVATE PARTNERSHIPS: THE 

EVOLVING ROLE OF INDUSTRY FUNDING IN 

NUTRITION RESEARCH

Symposium

(Sponsored by: Dairy Research Institute)

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Research Methods and Funding

Career Development

8:00 Introduction. 

E. Hentges. Natl. Life Sci. Inst., North 

America.

8:24 

Public-private research funding from an academic 

perspective. 

J. O. Hill. Univ. of Colorado Sch. of Med.

8:48 

Industry funded research: opportunities and challenges. 

R. Black. Kraft Foods Inc.

9:12 

Alternative models to traditional research funding: 

key learning from the Foundation for the National 

Institutes of Health. 

M. Vassileva. Fndn. for NIH.

9:36 

Panel discussion moderated by the chairs of the 

Session. 

J. Zachwieja. Dairy Res. Inst.

341.  BUILDING EVIDENCE FOR SUSTAINABILITY 

OF FOOD AND NUTRITION INTERVENTION 

PROGRAMS IN DEVELOPING COUNTRIES

Symposium

(Sponsored by: Global Nutrition Council)

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Global and Public Health Nutrition

8:00 

Overview of frameworks for conceptualizing program 

sustainability. 

S. S. Kim. Natl. Food Policy Res. Inst.

8:24 

Promoting sustainability in food aid programs: results 

from Bolivia and Honduras and lessons learned for 

future programming. 

B. L. Rogers. Tufts Univ.

8:48 

Key factors for promoting sustainability in food aid 

programs: hypotheses and results from Kenya. 

J. 

Coates. Tufts Univ.

9:12 

Sustainability of impact: adoption and consumption of a 

biofortified crop in Uganda. 

D. O. Gilligan. Natl. Food 

Policy Res. Inst.

9:36 

Modeling impact of a pro-sustainability investment 

strategy in a child survival project in Guinea: 

applications for sustainability planning of health, food 

security and nutrition programs. 

E. Sarriot. CEDARS, 

ICF Natl.

TUESDAY NUTRITION

92

9:30 

343.7 

Body fat distribution in preterm and term born 

children at school age. 

E. Landmann, V. Huke, M. Brugger, 

K. Strauch, L.D. Berthold and S. Rudloff. Justus Liebig Univ. 

Giessen, Helmholtz Ctr. Munich and Ludwig Maximilian Univ., 

Neuherberg.

9:45 

343.8 

Association of fat distribution with changes in 

bone outcomes in young girls. 

D. Laddu, V.R. Lee, R.M. Blew 

and S.B. Going. Univ. of Arizona.

344.  NUTRITION EDUCATION IN DIVERSE 

POPULATIONS

Minisymposium

(Sponsored by: Nutrition Education RIS)

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8:00 

344.1 

Understanding dietary behaviors of children 

with type 1 diabetes using theory of planned behavior. 

S-K. 

Lee, N-Y. Noh, S-Y. Nam, H-S. Kang and J-E. Lee. Inha Univ. 

and Inha Univ. Hosp., South Korea.

8:15 

344.2 

Impact of “en balance” culturally sensitive 

educational program on lifestyle changes among Hispanics 

with type 2 diabetes. 

A.A. Al Abdrabalnabi, A.A. Marghalani, 

L. Beeson, A. Firek, E. Schulz, M. De Leon, H. Balcazar and 

Z.R. Cordero-MacIntyre. Loma Linda Univ. Sch. of Publ. Hlth. 

and Sch. of Med. and Univ. of Texas Sch. of Publ. Hlth., El Paso.

8:30 

344.3 

Using a culturally-tailored sugar screening tool 

to give dietary recommendations for reducing sugar intake in 

Mexican-American adults. 

A. Chavez, A.E. Parra, M. Robles, 

L.R. Flores, L. Leander and S. Vega-López. Sch. of Nutr. and 

Hlth. Promotion, Arizona State Univ.

8:45 

344.4 

Caregiver’s knowledge of sugar sweetened 

beverages is associated with availability of this type of 

beverages in the home. 

C. Quesada, E. Schilling, A. Ferris 

and K. Lora. Univ. of Connecticut Hlth. Ctr., East Hartford and 

Univ. of Oklahoma Hlth. Sci. Ctr.

9:00 

344.5 

An Italian obesity prevention intervention study 

in teenagers: the EAT project. Effectiveness of a school-based 

program on measures of fatness and behavior over 2 school 

years. 

M.M. Corsi Romanelli, A.E. Malavazos, S. Briganti, F. 

Ermetici, R. Zelaschi, C. Oggioni, S. Goggi, D. Ignaccolo, M. 

Kapeoldasi, G. Romeo, S. Vazzoler, E. Dozio, L. Morricone 

and G. Pelissero. Univ. of Milan and IRCCS Polyclin. San 

Donato, Milan.

9:15 

344.6 

Ghanaian caregivers’ opinions on feeding 

2- to 5-year-old children varies by agro-ecological zone. 

A.K. 

Christian, E. Colecraft, G.S. Marquis, A. Lartey, O. Sakyi-

Dawson, L.M. Butler, B. Ahunu, M.B. Reddy, H.H. Jensen 

and E.J. Huff-Lonergan. Univ. of Ghana, McGill Univ., Ste. 

Anne de Bellevue and Iowa State Univ.

9:30 

344.7 

Acculturation and food label use among Korean 

immigrants in New York City. 

H.J. Shim, C. Doak and S. Jasti. 

Queens Col., NY and VU Univ., Amsterdam.

9:45 

344.8 

Effect of web-based self-reporting of dietary 

intake on college students’ self-efficacy. 

J. Leibowitz, B. 

Cunningham, A. Dols, E. Dumm, A. Eng, K. Franke, A. Gross, 

J. Helinek, J. Indig, A. O’Connor, T. Russell, A. Sharma and 

N. Sahyoun. Univ. of Maryland College Park.

345.  ANIMAL RESEARCH MODELS FOR 

MACRONUTRIENT METABOLISM

Minisymposium

(Sponsored by: Experimental Animal Nutrition RIS)

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8:00 

345.1 

Effect of gender on long-term effects of catch-

up growth in neonatal rats. 

E. Ebanks, B. Lonnerdal and I.J. 

Griffin. Univ. of California, Davis and Sacramento.

8:15 

345.2 

Food intake modulation by hop phytoestrogen 

in overweight neutered cats. 

R.C. Backus, G.E. Rottinghaus, 

D.P. Shaw and I. Jeusette. Univ. of Missouri-Columbia and 

Affinity-Petcare, Barcelona.

8:30 

345.3 

Lean body mass and loci containing genes 

involved in insulin and glucose regulation are associated 

with calorie intake in dogs. 

D.E. Jewell, J.A. Brockman, M.J. 

Huentelman, C.B. Kingsley, A.L. Siniard, R. Richholt and 

J.A. Hall. Hill’s Pet Nutr., Topeka, Translational Genomics Res. 

Inst., Phoenix and Oregon State Univ.

8:45 

345.4 

Effect of dietary mannoheptulose on whole 

body glucose and energy metabolism in adult neutered male 

Labrador Retrievers. 

L.L. McKnight, E.A. Flickinger, G. 

Davenport, J. France and A.K. Shoveller. Univ. of Guelph, 

Canada and Procter & Gamble Pet Care, Mason, OH.

9:00 

345.5 

Consumption of different sources of omega-3 

fatty acids alters lipogenic gene expression in growing rats. 

K. 

Mock, J. Tou, V. Benedito and J. Gigliotti. West Virginia Univ.

9:15 

345.6 

The effect of non-marine versus marine 

sources of the omega-3 fatty acids, DHA and EPA, on serum 

lipoproteins. 

M.C. Rodavich, J.S. Ketz and K.M. Barnes. West 

Virginia Univ.

9:30 

345.7 

Biochemical and metabolomic effects of 

perinatal choline deficiency in the piglet. 

C.M. Getty and R.N. 

Dilger. Col. of Vet. Med., Univ. of Illinois, Urbana.

9:45 

345.8 

Protein turnover in pregnant pigs at amino 

acid intake in excess of requirements. 

S. Moehn, M. Rafii, P.B. 

Pencharz and R.O. Ball. Univ. of Alberta and The Hosp. for 

Sick Children, Toronto.

346.  NUTRITION AND COGNITION ACROSS THE 

LIFESPAN

Minisymposium

(Sponsored by: Aging and Chronic Disease RIS)

(Cosponsored by: Nutritional Epidemiology RIS)

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346.1 

Infant iodine supplementation and motor 

and cognitive development: a randomized controlled trial.