I 640.1 ALOX5 gene variations modulate
plasma triglyceride levels during an n-3 polyunsaturated fatty
acid supplementation.
H. Cormier, I. Rudkowska, P. Julien,
P. Couture, S. Lemieux and M-C. Vohl. Laval Univ. and Laval
Univ. Med. Ctr., Canada.
D404
II 640.2 Adult-onset obesity induced by early life
overnutrition could be reversed by caloric restriction.
H-W. Liu,
S. Mahmood, M. Srinivasan, D.J. Smiraglia and M. Patel.
Univ. at Buffalo and Roswell Park Cancer Inst.
D405
I 640.3 Polyunsaturated fatty acids (pufa)
modulate association between PIK3CA-KCNMB3 variants and
insulin resistance.
J-S. Zheng, D.K. Arnett, L.D. Parnell, Y-C.
Lee, Y. Ma, C.E. Smith, K. Richardson, D. Li, I.B. Borecki,
K.L. Tucker, J.M. Ordovás and C-Q. Lai. Zhejiang Univ.,
China, USDA at Tufts Univ., Univ. of Alabama at Birmingham,
Washington Univ. Sch. of Med. and Northeastern Univ.
D406
II 640.4 Oral administration of nutrients recovers
intestinal functions in total parenteral nutrition model of rats.
T. Suzuki, A. Kasahara, A. Keta, A. Sato and Y. Mayanagi.
Yamagata Univ., Japan.
D407
I 640.5 Zinc supplementation increases
expression of transcription factors PU.1, KLF4, and Nrf2 in the
lungs of alcohol-fed rats.
P.C. Joshi, X. Fan, M. Koval and D.M.
Guidot. Emory Univ. Sch. of Med. and Atlanta VA Med. Ctr.
D408
II 640.6 In vivo regulation of gene transcription
by alpha and gamma-tocopherol in murine T lymphocytes.
J-M.
Zingg, S.N. Han, E. Pang, M. Meydani, S.N. Meydani and A.
Azzi. USDA at Tufts Univ. and Seoul Natl. Univ.
D409
I 640.7 Association of dietary and supplemental
folate intake and polymorphisms of the MTHFR, MTHFD1, and
TYMS genes and colorectal cancer in a population-based study.
J.H. Ashmore, A. Berg, C. Gallagher, P. Miller, J. Muscat, J.
Zhu, T. Hartman, P. Lazarus and S. Lesko. Penn State, Penn
State Col. of Med., Exponent Inc., Chicago and Northeast Reg.
Cancer Inst., Scranton, PA.
D410
II 640.8 Conjugated linoleic acid reduces
adiposity and increases markers of browning and inflammation
in white adipose tissue of mice.
W. Shen, C-C. Chuang, K.
Martinez, T. Reid, J.M. Brown, L. Xi, L. Hixson, J. Starnes
and M. McIntosh. Univ. of North Carolina at Greensboro,
Wake Forest Sch. of Med. and North Carolina State Univ.
D411
I 640.9 Effects of Cfh genotype and dietary
glycemic index on age-related macular degeneration in mice.
S. Rowan, K. Weikel, M-L. Chang, B. Nagel, J. Thinschmidt,
M. Grant, S. Fliesler and A. Taylor. USDA at Tufts Univ., Saint
Louis Univ., Univ. of Florida and Univ. at Buffalo SUNY.
D412
II 640.10 Cardiometabolic risk factors are
influenced by stearoyl-CoA desaturase-1 polymorphisms
and n-3 polyunsaturated fatty acids supplementation.
I.
Rudkowska, P. Julien, P. Couture, S. Lemieux and M-C.
Vohl. Laval Univ. and Laval Univ. Med. Ctr., Canada.
D413
I 640.11 Effects of acute Pils-beer consumption
on alcohol-induced liver steatosis in a mouse model.
M.
Landmann, G. Kanuri and I. Bergheim. Inst. of Nutr. Med.,
Stuttgart and Inst. of Nutr., Jena, Germany.
SUNDAY NUTRITION
186
D414
II 640.12 One-carbon metabolism related
B-vitamins alter the expression of microRNAs associated with
the Wnt pathway in mouse colonic epithelium.
E. Mohn, X. Ma,
B. Lee, S-W. Choi, J.W. Crott, C-q. Lai and Z. Liu. Friedman
Sch. of Nutr. Sci. and Policy and USDA at Tufts Univ. and Univ.
of Massachusetts Amherst Sch. of Publ. Hlth. and Hlth. Sci.
D415
I 640.13 Genome-wide association study on
coffee intake in Korea population.
J.K. Lee, J. Sung, K. Kim
and J.E. Lee. Sookmyung Women’s Univ., South Korea and
Grad. Sch. of Publ. Hlth., Seoul Natl. Univ.
D416
II 640.14 High ferritin and low folate increases
PBMCs genomic DNA methylation in association with SHMT1-
1420TT variant.
S. Moruzzi, P. Guarini, S. Udali, O. Olivieri,
D. Girelli, P. Pattini, F. Pizzolo, S.W. Choi and S. Friso. Univ.
of Verona and USDA at Tufts Univ.
D417
I 640.15 Chronic alcohol consumption has
greater impact on hepatic DNA hydroxymethylation in young
mice relative to old.
S.A. Tammen, G.G. Dolnikowski, L.M.
Ausman, J. Sauer, S. Friso and S-W. Choi. Friedman Sch. of
Nutr. Sci. and Policy and USDA at Tufts Univ. and Sch. of Med.,
Univ. of Verona.
D418
II 640.16 Vitamin A-mediated inhibition of cell
cycle progression proteins and cell growth requires protein-
bound retinol in a prostate cancer cell line.
C.E. Schulte and
M.J. Rowling. Iowa State Univ.
D419
I 640.17 Selection of reference gene for qPCR
analysis of hypothalamic appetite regulation.
D.L. Colley and
T.W. Castonguay. Univ. of Maryland College Park.
D420
II 640.18 Effects of
g-glutamyl hydrolase
modulation on CpG promoter DNA methylation and gene
expression in human colon cancer cells.
S-E. Kim, T. Hinoue,
M. Kim, K-J. Sohn, R. Cho, D. Weisenberger, P.W. Laird and
Y-I. Kim. Univ. of Toronto, Univ. of Southern California and St.
Michael’s Hosp., Toronto.
D421
I 640.19 Genetic regulation of impaired fasting
glucose in congenic mice.
J.H. Kim, X. Mao, T. Stewart and K.
Dillon. Marshall Univ. Sch. of Med.
D422
II 640.20 Differential gene regulation by nutrient
restriction and hypoxia in cultured human placental extravillous
trophoblasts (HTR-8/SVneo).
S. Jones and P.M. Brannon.
Cornell Univ.
D423
I 640.21 SELP variant modulates plasma HDL-C
responses in subjects with moderate cardiovascular risk after
skimmed milk consumption.
P. Casas-Agustench, S. Molina,
I. Espinosa-Salinas, M. Olivares, G. Reglero, J.M. Ordovás
and A. Ramírez de Molina. USDA at Tufts Univ., UAM+CSIC,
Madrid, Puleva Biotech SA and Biosearch SA, Granada, Spain.
D424
II 640.22 Effect of early life Ca and P restriction
on renal transporters gene expression in post-weaning piglets.
D.E. Graugnard, M.L. Spry, R.S. Samuel, J.S. Jolliff, D.C.
Mahan and K.M. Brennan. Alltech Inc., Nicholasville, KY and
The Ohio State Univ.
D425
I 640.23 Development of respiratory tract
infection could be modified by the interactions between maternal
diet during pregnancy and offspring’s CD14 (rs#2569190) and
VDR (rd#7975232) polymorphisms.
S.A. Hong, S.O. Kwon,
K.W. Kim, Y.H. Shin, K.M. Ahn, J. Yu, J-Y. Kwon, S-J. Choi,
K-J. Lee, H-S. Won, S-y. Oh and S-J. Hong. Univ. of Ulsan Col.
of Med., Kyung Hee Univ., Yonsei Univ., Pochon CHA Univ. Col.
of Med., Sungkyunkwan Univ. Sch. of Med., South Korea.
D426
II 640.24 A bioinformatic rational gene targeting
approach to treating pathologies with healthy diet.
A. Saxena,
L. Gao and D. Crawford. RPI and Albany Med. Col.
D427
I 640.25 Identification of variants in the fatty
acid desaturase gene cluster associated with total cholesterol
and HDL-C in young Mexican college students: UP-AMIGOS
study.
I. Vazquez-Vidal, M. Teran-Garcia, F.C.D. Andrade, C.
Aradillas-Garcia and J.M. Vargas-Morales. Univ. of Illinois,
Urbana and Sch. of Med. and Sch. of Chem., Autonomous Univ.
of San Luis Potosi, Mexico.
641. NUTRIENT EFFECTS ON STEM CELL
DIFFERENTIATION AND GENE EXPRESSION
Poster
(Sponsored by: Nutrient-Gene Interactions RIS)
s
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. 7:30
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Presentation time: 12:45
pm
-1:45
pm
(I); 1:45
pm
-2:45
pm
(II)
D428
I 641.1 Accelerated growth during infancy
alters bone characteristics and the activity of mesenchymal
stem cells in neonatal piglets.
B. Seabolt, Y. Li and C. Stahl.
North Carolina State Univ.
D429
II 641.2 Intestinal adaptation to diet-induced
obesity involves an increase in intestinal epithelial stem cells
but impaired stem cell function.
A. Mah, L. Van Landeghem,
H. Gavin and P.K. Lund. Univ. of North Carolina at Chapel Hill.
D430
I 641.3 Identification of miR-26b and miR-203
gene targets in colon cancer cells.
M.S. Shah, L.A. Davidson
and R. Chapkin. Texas A&M Univ.
D431
II 641.4 Acetyl-CoA carboxylases are
checkpoints in adipocyte differentiation.
E.L. Cordonier, D.
Camara Teixeira, Z. Han, A.K. Pannier and J. Zempleni. Univ.
of Nebraska-Lincoln.
642. REGULATION OF INTESTINAL NUTRIENT
METABOLISM AND GENE EXPRESSION
Poster
(Sponsored by: Nutrient-Gene Interactions RIS)
s
un
. 7:30
am
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C
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& e
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C
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Presentation time: 12:45
pm
-1:45
pm
(I); 1:45
pm
-2:45
pm
(II)
D432
I 642.1 Dietary protein diet prevents high fat-
induced intestinal adaptation and thereby increases intestinal
lipid uptake rates in mice.
J. Schwarz, D. Tomé, M.R. Müller
and G.J.E.J. Hooiveld. Wageningen Univ., Netherlands and
AgroParisTech INRA.
D433
II 642.2 Ca
v
1.3 does not contribute to active
1,25D-regulated intestinal Ca absorption.
P.C. Reyes
Fernandez, R.A. Replogle, Q. Li and J.C. Fleet. Purdue Univ.
D434
I 642.3 High intestinal calcium absorption
efficiency is positively associated with bone mass in a
genetically diverse population of mice.
R.A. Replogle, Q. Li
and J.C. Fleet. Purdue Univ.
NUTRITION SUNDAY
187
S
U
N
643. NUTRITIONAL IMMUNOLOGY
Poster
(Sponsored by: Nutritional Immunology RIS)
s
un
. 7:30
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C
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Presentation time: 12:45
pm
-1:45
pm
(I); 1:45
pm
-2:45
pm
(II)
D435
I 643.1 Epithelial transport of immunogenic and
toxic gliadin peptides in vitro.
C.A. Zimmermann, S. Arampatzi,
W. Maison, G. Lochnit, K-P. Zimmer and S. Rudloff. Univ. of
Giessen, Germany.
D436
II 643.2 Circulating pro-inflammatory cytokines
are elevated and peak power output correlates with
25-hydroxyvitamin D in vitamin D insufficient adults.
T. Barker,
B.M. Dixon, E.D. Schneider and L.K. Weaver. Orthoped.
Specialty Hosp., Murray, USANA Hlth. Sci. Inc., Salt Lake City
and LDS Hosp. and Intermountain Med. Ctr., Murray, UT.
D437
I 643.3 Fish oil differentially regulates B cell and
dendritic cell activation in response to a T-independent antigen.
H. Teague, B.D. Rockett, M. Harris and S.R. Shaikh. East
Carolina Univ.
D438
II 643.4 EPA and DHA do not exert equivalent
effects on B lymphocyte plasma membrane organization:
implications for developing biomarkers of fish oil for targeting B
cell immunity.
H. Teague, E. Gurzell, B.D. Rockett, J. Fenton
and S.R. Shaikh. East Carolina Univ. and Michigan State Univ.
Col. of Osteo. Med.
D439
I 643.5 Modulating dietary vitamin A altered the
pathogenicity of Citrobacter rodentium in mice.
A.D. Smith and
L. Cheung. USDA, Beltsville.
D440
II 643.6 Nutritional and immunological lessons
learned from the porcine genome.
H.D. Dawson. USDA,
Beltsville.
D441
I 643.7 Immuno-stimulating activities of
polysaccharides from Korean red ginseng in cyclophsphamide-
treated immunosuppressed mice.
C-W. Cho, C-j. Han, H-D.
Hong, Y.K. Rhee, S-H. Nam, S-K. Sung, J. Rho, S.Y. Choi
and Y-C. Lee. Korea Food Res. Inst., seongnam-si and Col. of
Med., Yanbian Univ., China.
D442
II 643.8 Immune-enhancing effects
of polysaccharides isolated from Cheonggukjang in
immunosuppressed mice.
H-D. Hong, C-J. Han, C-W. Cho,
Y.K. Rhee, S-H. Nam, S-K. Sung, Y-C. Kim and K. Kim. Korea
Food Res. Inst., Seongnam and Col. of Med., Yanbian Univ.,
China.
D443
I 643.9 Effects of frequent sweetener intake
on murine splenic T lymphocyte surface marker expression.
M. Sánchez-Delgado, J.A. Estrada, J. Serrano-Váldes, R.
Váldes-Ramos and I. Contreras. Fac. of Med., Autonomous
Univ. of Mexico State, Toluca.
D444
II 643.10 Changes in leukocyte populations
among children receiving a follow-on cow’s milk-based formula
containing beta-glucan.
N. Sarvetnick, K. Murphy, R. Pauley-
Hunter and D. Scalabrin. Univ. of Nebraska Med. Ctr., Boys
Town Natl. Res. Hosp., NE and Mead Johnson Pediat. Nutr.
Inst., Evansville.
D445
I 643.11 Changes in leukocyte populations
among children receiving a follow-on cow’s milk-based formula
containing Lactobacillus rhamnosus GG.
N. Sarvetnick,
K. Murphy, R. Pauley-Hunter and D. Scalabrin. Univ. of
Nebraska Med. Ctr., Boys Town Natl. Res. Hosp., NE and Mead
Johnson Pediat. Nutr. Inst., Evansville.
D446
II 643.12 Microbial metabolites produced by the
colonic microbiota as drivers for immunomodulation in the host.
K. Venema. Top Inst. Food & Nutr., Wageningen, Netherlands.
D447
I 643.13 The influence of type II diabetes on the
immune response of obese adults.
H.A. Paich, P.A. Sheridan,
T.L. Noah, S.S. Weir and M.A. Beck. Univ. of North Carolina at
Chapel Hill.
D448
II 643.14 Consumer knowledge, attitudes and
behaviors about foods that have immune benefits: focus on
mushrooms.
C. Tejera, L.A. House and S.S. Percival. Univ. of
Florida.
D449
I 643.15 Consumption of Lentinula edodes
modulates human immune function by altering cytokine
secretion of PBMC ex vivo.
X. Dai, J.M. Stanilka, C.A. Rowe,
R.A. Creasy and S.S. Percival. Univ. of Florida.
D450
II 643.16 Inhibitory effects of resveratrol on IgE-
mediated degranulation and anaphylactic reaction in basophilic
mast cells and mice.
S-Y. Han and Y-H. Kang. Hallym Univ.,
South Korea.
D451
I 643.17 Lentinula edodes consumption:
proliferation, activation and modification of memory and naive
innate immune cell populations.
J.M. Stanilka, C.A. Rowe,
R.A. Creasy, X. Dai and S.S. Percival. Univ. of Florida.
D452
II 643.18 Chronic administration of low dose
EGCG inhibits TNF-
a-induced IL-6 and IL-8 production in
rheumatoid arthritis synovial fibroblasts.
S. Riegsecker and S.
Ahmed. Univ. of Toledo.
D453
I 643.19 The effect of calorie restriction with and
without curcumin supplementation on inflammatory and T cell-
mediated immune responses of obese mice.
J. Wang, S.M.
Vanegas, X. Du, T. Noble, J-M.A. Zingg, M. Meydani, S.N.
Meydani and D. Wu. USDA at Tufts Univ.
D454
II 643.20 The role of insulin in glucose transporter
expression, proliferation and effector function in human CD4
+
and CD8
+
T cells.
H. Meng, A.J. Black and C.J. Rogers. Penn
State.
D455
I 643.21 Natural killer cell cytotoxicity is reduced
in aged female mice fed a high folic acid diet.
H. Sawaengsri,
J. Wang, N. Desautels, J. Steluti, A. Histed, D. Smith, D. Wu,
S.N. Meydani, J. Selhub and L. Paul. USDA and Friedman
Sch. of Nutr. Sci. and Policy, Tufts univ.
644. NUTRIENT-GENE INTERACTION IN
NEURODEGENERATIVE DISEASES: ROLE OF
VITAMIN D
Poster
(Sponsored by: Nutrient-Gene Interactions RIS)
s
un
. 7:30
am
—B
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C
onvention
& e
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Presentation time: 12:45
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pm
(I); 1:45
pm
-2:45
pm
(II)
7:30 AMD456
I 644.1 Dietary vitamin D 3
supplementation at 50x the adequate intake decreases
calbindin d28k and endoplasmic reticulum stress and increases
apoptosis, suggesting toxicity, in the female transgenic G93A
mouse model of amyotrophic lateral sclerosis.
S. Taheri-
Shalmani, S. Shahsavar, A. Gianforcaro, J.A. Solomon and
M.J. Hamadeh. Sch. of Kinesiol. and Hlth. Sci., York Univ.,
Canada.
SUNDAY NUTRITION
188
7:31 AMD457
II 644.2 Sexual dichotomy in
calcium buffering capacity may be dependent on the severity
of endoplasmic reticulum stress in the skeletal muscle of
the vitamin D3-deficient transgenic G93A mouse model
of amyotrophic lateral sclerosis.
S. Shahsavar, S. Taheri-
Shalmani, J.A. Solomon, A. Gianforcaro and M.J. Hamadeh.
Sch. of Kinesiol. and Hlth. Sci., York Univ., Canada.
7:32 AMD458
I 644.3 Skeletal muscle vitamin D
receptor associated with serum 25-hydroxyvitamin D .
R.M.
Pojednic, L. Ceglia, A. Lichtenstein, B. Dawson-Hughes
and R. Fielding. USDA at Tufts Univ. and Tufts Med. Ctr.
Pathology
645. INFLAMMATION
Poster
s
un
. 7:30
am
—B
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C
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Presentation time: 11:45
am
-1:45
pm
A390
645.1
Lower natural killer cell cytotoxicity in smokers
may be mediated by epithelial cells.
L. Muller, L.E. Brighton
and I. Jaspers. Univ. of North Carolina at Chapel Hill.
A391
645.2
Human airway epithelial cells and alveolar
macrophages coordinate the innate immune response to acute
ozone exposure.
R.N. Bauer, K. Duncan, D. Diaz-Sanchez, M.
Hernandez and I. Jaspers. Univ. of North Carolina at Chapel
Hill and U.S. EPA, Chapel Hill.
A392
645.3
Modeling long-term host cell-Giardia lamblia
interactions in an in vitro 3D cell culture system.
B.S. Fisher, C.
Estrano and J. Cole. Univ. of Memphis.
A393
645.4
Cytokine profile in celiac disease: a laser
capture microdissection approach.
G. Iaquinto, V. Rotondi
Aufiero, M. Preziuso, A. Marano, I. Stillitano, N. Giardullo,
R.M. Bevilacqua, P. Iacomino and G. Mazzarella. San G.
Moscati Hosp. and Natl. Council Res., Avellino, Italy.
A394
645.5
Combined Foxp3 and IgG4 staining reveal
distinct subsets of inflammatory bowel disease.
M.A. Seidman
and A.M. Bellizzi. Brigham and Women’s Hosp., Harvard Med.
Sch. and Univ. of Iowa Hosps. and Clins., Carver Col. of Med.
A395
645.6
Identification and assessment of regulatory T
cells (Treg*) associated with inflammation and tumorigenesis
in inflammatory bowel disease patients.
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