OXYGEN CONSUMPTION IN THE LUNGS AND SYSTEMIC CIRCULATION – DIFFERENT METHODS OF
MEASUREMENT OF ONE DATA OR DIFFERENT DATA?
Perfilova A.V., Gromova T.A., Lebedinskii K.M., Zaichik A.M.
Mechnikov North-Western State Medical University, Saint-Petersburg, Russia
correspondence to: Perfilova Anna Vladimirovna
e-mail:
aperfilova@gmail.com
Abstract:
The article deals with calculation of oxygen consumption in the lungs by means of breathing gas
mixture analysis and in parallel – in the systemic circulation by reverse Fick method; 32 paired
measurements were performed in 8 patients after cardiac surgery with cardiopulmonary bypass. The mean
pulmonary oxygen consumption was higher than the same value calculated by the reverse Fick principle –
148.4±39.9 ml·min
−
1
·m
−
2
and 120±35.1 ml·min
−
1
·m
−
2
, respectively, the mean difference between two
methods was 28.4±18.4 ml·min
−
1
·m
−
2
. However, in two observations the interrelation was inversed. While
analyzing physiological and methodological reasons for these differences, the authors concluded that,
despite both methods can be used in monitoring systemic oxygen transport in the critically ill, they are not
interchangeable, and valuable additional data could be derived from fast changes in lungs oxygen uptake.
Key words:
oxygen consumption, reverse Fick principle, ventilation–perfusion relationship
AN-1401-047
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