Anthrax
Treatment
Acute
OR
» moxifloxacin
: 400 mg orally once daily
OR
» levofloxacin
: 750 mg orally once daily
OR
» doxycycline
: 100 mg orally twice daily
OR
» amoxicillin
: 1000 mg orally three times daily
Secondary options
» clindamycin
: 600 mg orally three times daily
»
After completing at least 2-3 weeks of
intravenous therapy, patients can be switched to
single-agent oral therapy if the patient is deemed
to be stable, to complete a total course of 60
days of treatment.
»
Amoxicillin should only be used if
B anthracis
is sensitive to penicillin.
adjunct
supportive care
»
Mechanical ventilation, haemodynamic
support, and adjunctive corticosteroid therapy
may be recommended depending on the clinical
presentation. There are limited data to support
the use of corticosteroids; however, intravenous
dexamethasone is the standard of care in
patients with bacterial meningitis, and it may
be considered in select patients with anthrax
meningitis.
[60]
TR
E
AT
M
E
N
T
This PDF of the BMJ Best Practice topic is based on the web version that was last updated: Aug 08, 2018.
BMJ Best Practice topics are regularly updated and the most recent version
of the topics can be found on bestpractice.bmj.com . Use of this content is
subject to our disclaimer. © BMJ Publishing Group Ltd 2018. All rights reserved.
Dostları ilə paylaş: 
