Organizing co mmittee

1
), gallic acid (
2
), digallic acid (
3
), quercetin (
4
), guajaverin (
5
), 
avicularin (
6
), hyperin (
7
), rutin (
8
), quercetin 3-O-robinobioside (
9
). 
The chemical structures of the isolated compounds were established based on the 
analysis of their spectral (UV, IR, 
1
H, 
13
C, and 2D NMR) data and comparison with 
literature data. 

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Poster presentation 
109 
CHEMICAL COMPONENTS OF Ferula tadshikorum 
 
Q.S. Juraev, 
Kh.I. Khasanova, 
B.J. Komilov, K.A. Eshbakova
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of the 
Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail] 
 
Ferula tadshikorum
belongs to the family 
Apiaceae
and is a widespread medicinal 
plant growing in Uzbekistan. 
F. tadshikorum
has been used as a medicinal plant in 
medicine since ancient times. The use of 
F.tadshikorum
in folkmedicine has also a 
centuries-old history. Since ancient times, the species has been used as an analgesic 
agent for arthritis and joint pain. Pharmacological studies have shown that the plant 
exhibits expectorant and anticonvulsant properties in exudativediathesis, pulmonary 
tuberculosis, otitis, lymphadenitis. Some studies have shown an effective effect of the 
plant in malignant tumors and syphilis, for which the leaves of the plant are mixed with 
acidic milk. In veterinary practice, a porridge obtained from the roots of 
F.tadshikorum
, 
prepared with boiling water, is used as a wound healing agent in skin diseases of 
domestic animals. The population also eats young stems in spring in the form of salads 
and as a filling of green dolma. Leaves in dry form are used to feed cattle [1].
We studed the roots (6,5 kg) of the 
F. tadshikorum
plant collected in the 
Surxandaryo region of Uzbekistan. Extracted with 70% alcohol at room temperature. 
The obtained alcohol extract was chromatographed on a silica gel column using a 
chloroform and methanol (9:1, 4:1, 2:1) gradient system were isolated scopoletin, 8-
hydroxycoumarin, 8-methoxycoumarin. The chemical structures of the isolated 
compounds were established on the basis of the spectral data of 
1
H, 
13
C NMR, 2D.
These compounds from 
F. tadshikorum
are isolated for the first time. 
Reference
1. Sharopov F.S, Khalifaev P.D, Satyal P, et al. The chemical composition and 
biological activity of the essential oil from the underground parts of 
Ferula tadshikorum
 
(
Apiaceae)
[J]. 
Records of Natural Products;
2019, 13: 18-23 
H
3
CO
O
O
HO
O
O
OH
O
O
OCH
3
Scopoletin
8-Hydroxycoumarin
8-Methoxycoumarin 

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Poster presentation 
110