1C352 Animal pathogens, as follows (see List of Items Controlled).
a. Viruses, as follows:
a.1. African swine fever virus as having high pathogenicity (HP), as follows:
a.2. Avian influenza (AI) viruses identified as having high pathogenicity (HP), as follows:
a.2.a. AI viruses that have an intravenous pathogenicity index (IVPI) in 6-week old chickens greater than 1.2; or a.2.b. AI viruses that cause at least 75% mortality in 4- to 8-week old chickens infected intravenously.
Note: Avian influenza (AI) viruses of
the H5 or H7 subtype that do not have either of
the characteristics described in 1C352.a.2
(specifically, 1C352.a.2.a or a.2.b) should be
sequenced to determine whether multiple basic
amino acids are present at the cleavage site of
the haemagglutinin molecule (HA0). If the
amino acid motif is similar to that observed for
other HPAI isolates, then the isolate being tested
should be considered as HPAI and the virus is
controlled under 1C352.a.2. a.3. Bluetongue virus;
organisms, as follows (see List of Items Controlled).
a. Genetic elements, as follows:
a.1. Genetic elements that contain nucleic acid sequences associated with the pathogenicity of microorganisms controlled by 1C351.a to .c, 1C352, or 1C354, acid sequences coding for any of the “toxins” controlled by 1C351.d or “sub-units of toxins” thereof.
b. Genetically modified organisms, as follows:
b.1. Genetically modified organisms that contain nucleic acid sequences associated with the pathogenicity of microorganisms controlled
by 1C351.a to .c, 1C352, or 1C354;
b.2. Genetically modified organisms that contain nucleic acid sequences coding for any of the “toxins” controlled by 1C351.d or “sub-units of toxins” thereof.
Technical Notes:
1. “Genetic elements” include, inter alia, chromosomes, genomes, plasmids, transposons, and vectors, whether genetically modified or unmodified, or chemically synthesized in whole or in part. 2. This ECCN does not control nucleic acid sequences associated with the pathogenicity of enterohaemorrhagic Escherichia coli, serotype O157 and other verotoxin producing strains, except those nucleic acid sequences that contain
coding for the verotoxin or its sub-units. 3. “Nucleic acid sequences associated with the pathogenicity of any of the microorganisms controlled by 1C351.a to .c, 1C352, or 1C354” means any sequence specific to the relevant
controlled microorganism that:
a. In itself or through its transcribed or translated products represents a significant hazard to human, animal or plant health; or
b. Is known to enhance the ability of a microorganism controlled by 1C351.a to .c, 1C352, or 1C354, or any other organism into
which it may be inserted or otherwise integrated, to cause serious harm to human, animal or plant health. 4. “Genetically modified organisms” include organisms in which the genetic material (nucleic acid sequences) has been altered in a way that does not occur naturally by mating and/or
natural recombination, and encompasses those produced artificially in whole or in part.
a.2. Xanthomonas axonopodis pv. citri (Xanthomonas campestris pv. citri A) (Xanthomonas campestris pv. citri); a.3. Xanthomonas oryzae [this species of proteobacteria is identified on the APHIS “select agents” list (see Related Controls paragraph for this ECCN), but only the pathovar Xanthomonas oryzae pv. oryzae (syn. Pseudomonas campestris pv. oryzae) is identified on the Australia Group (AG) “List of Plant Pathogens for Export Control”];
a.6. Raythayibactor toxicus [this bacterium is identified on the APHIS “select agents” list (see the Related Controls paragraph for this ECCN), but is not identified on the Australia Group (AG) “List of Plant Pathogens for Export Control”].
b. Fungi, as follows:
b.1. Colletotrichum kahawae (Colletotrichum coffeanum var. virulans);
b.12. Phoma glycinicola (formerly Pyrenochaeta glycines) [this fungus is identified on the APHIS “select agents” list (see the Related Controls paragraph for this ECCN), but is not identified on the Australia Group (AG) “List of Plant Pathogens for Export Control”].
2A226 Valves having all of the following characteristics
a. A “nominal size” of 5 mm or greater;
b. Having a bellows seal; and
c. Wholly made of or lined with aluminum, aluminum alloy, nickel, or nickel alloy containing more than 60% nickel by weight.
2A292 Piping, fittings and valves made of, or
lined with, stainless steel, copper-nickel alloy
or other alloy steel containing 10% or more
nickel and/or chromium.
a. Pressure tube, pipe, and fittings of 200 mm (8 in.) or more inside diameter, and suitable for operation at pressures of 3.4 MPa (500 psi) or greater;
b. Pipe valves having all of the following characteristics:
b.1. A pipe size connection of 200 mm (8 in.) or more inside diameter; and
b.2. Rated at 10.3 MPa (1,500 psi) or more.
2A994 Portable electric generators and specially designed parts.
The list of items controlled is contained in the
ECCN heading.
2A999 Specific processing equipment, n.e.s., as follows (see List of Items controlled).
Note:NP applies to measuring systems in 2B006.b.1.c that maintain, for at least 12 hours, over a temperature range of ± 1 K around a standard temperature and at a standard pressure, all of the following: a “resolution” over their full scale of 0.1 μm or less (better); and a “measurement uncertainty” equal to or less
(better) than (0.2 + L/2,000) μm (L is the measured length in mm). a. Computer controlled or “numerically controlled” Coordinate Measuring Machines (CMM), having a three dimensional length (volumetric) maximum permissible error of length measurement (E0,MPE) at any point within the operating range of the machine (i.e., within the length of axes) equal to or less (better) than (1.7 + L/1,000) μm (L is the measured length in mm) according to ISO 10360-2 (2009);
Technical Note: The E0,MPEof the most accurate configuration of the CMM specified by the manufacturer (e.g., best of the following:
Probe, stylus length, motion parameters, environment) and with “all compensations available” shall be compared to the 1.7 + L/1,000 μm threshold.
b. Linear and angular displacement measuring instruments, as follows:
b.1. ‘Linear displacement’ measuring instruments having any of the following:
Note: Displacement measuring “laser” interferometers are only specified by 2B006.b.1.c. Technical Note: For the purpose of 2B006.b.1 ‘linear displacement’ means the change of distance between the measuring probe and the measured object. b.1.a. Non-contact type measuring systems with a “resolution” equal to or less (better) than 0.2 μm within a measuring range up to 0.2 mm;
b.1.b. Linear voltage differential transformer systems having all of the following:
b.1.b.1. “Linearity” equal to or less (better) than 0.1% within a measuring range up to 5 mm; and
b.1.b.2. Drift equal to or less (better) than 0.1% per day at a standard ambient test room temperature ± 1 K;
b.1.c. Measuring systems having all of the following:
b.1.c.1. Containing a “laser”; and
b.1.c.2. Maintaining, for at least 12 hours, at a temperature of 20 ± 1ºC, all of the following:
b.1.c.2.a. A “resolution” over their full scale of 0.1 μm or less (better); and
b.1.c.2.b. Capable of achieving a “measurement uncertainty”, when compensated for the refractive index of air, equal to or less (better) than (0.2 + L/2,000) μm (L is the measured length in mm); or
7A001 Accelerometers
a. Linear accelerometers having any of the following:
a.1. Specified to function at linear acceleration levels less than or equal to 15 g and having any of the following:
a.1.a. A “bias” “stability” of less (better) than 130 micro g with respect to a fixed calibration value over a period of one year; or
a.1.b. A “scale factor” “stability” of less (better) than 130 ppm with respect to a fixed calibration value over a period of one year;
a.2. Specified to function at linear acceleration levels exceeding 15 g but less than or equal to 100 g and having all of the following:
a.2.a. A “bias” “repeatability” of less (better) than 1,250 micro g over a period of one year; and
a.2.b. A “scale factor” “repeatability” of less (better) than 1,250 ppm over a period of one year; or
a.3. Designed for use in inertial navigation or guidance systems and specified to function at linear acceleration levels exceeding 100 g;
Note: 7A001.a.1 and 7A001.a.2 do not apply to accelerometers limited to measurement of only vibration or shock. b. Angular or rotational accelerometers, specified to function at linear acceleration
2B229 Centrifugal multiplane balancing machines, fixed or portable, horizontal or vertical, as follows (see List of Items Controlled).
a. Centrifugal balancing machines designed for balancing flexible rotors having a length of 600 mm or more and having all of the following characteristics:
a.1. Swing or journal diameter greater than 75 mm;
a.2. Mass capability of from 0.9 to 23 kg; and a.3. Capable of balancing speed of revolution greater than 5,000 r.p.m.;
b. Centrifugal balancing machines designed for balancing hollow cylindrical rotor components and having all of the following characteristics:
b.1. Journal diameter greater than 75 mm; b.2. Mass capability of from 0.9 to 23 kg;
b.3. Capable of balancing to a residual imbalance equal to or less than 0.01 kg x mm/kg per plane; and
b.4. Belt drive type.
2B352 Equipment capable of use in handling biological materials, as follows (see List of Items Controlled).
a. Complete containment facilities at P3 or P4
containment level.
Technical Note: P3 or P4 (BL3, BL4, L3,
L4) containment levels are as specified in the
WHO Laboratory Biosafety Manual (3rd edition,
Geneva, 2004). b. Fermenters capable of cultivation of pathogenic microorganisms, viruses, or for toxin production, without the propagation of aerosols, having a capacity equal to or greater than 20 liters.
Technical Note: Fermenters include bioreactors, chemostats, and continuous-flow systems.
c. Centrifugal separators capable of the continuous separation of pathogenic microorganisms, without the propagation of aerosols, and having all of the following characteristics:
c.1. One or more sealing joints within the steam containment area;
c.2. A flow rate greater than 100 liters per hour; c.3. Components of polished stainless steel or titanium; and
c.4. Capable of in-situ steam sterilization in a closed state
Technical Note: Centrifugal separators include decanters.
d. Cross (tangential) flow filtration equipment and accessories, as follows:
d.1. Cross (tangential) flow filtration equipment capable of separation of pathogenic microorganisms, viruses, toxins or cell cultures having all of the following characteristics:
d.1.a. A total filtration area equal to or greater than 1 square meter (1 m2); and
d.1.b. Having any of the following characteristics:
d.1.b.1. Capable of being sterilized or disinfected in-situ; or
d.1.b.2. Using disposable or single-use filtration components.
N.B.: 2B352.d.1 does not control reverse osmosis equipment, as specified by the manufacturer. d.2. Cross (tangential) flow filtration components (e.g., modules, elements, cassettes, cartridges, units or plates) with filtration area equal to or greater than 0.2 square meters (0.2 m2) for each component and designed for use in cross (tangential) flow filtration equipment controlled by 2B352.d.1.
Technical Note: In this ECCN, “sterilized” denotes the elimination of all viable microbes from the equipment through the use of either physical (e.g., steam) or chemical agents.
“Disinfected” denotes the destruction of potential microbial infectivity in the equipment through the use of chemical agents with a germicidal effect. “Disinfection” and “sterilization” are distinct from “sanitization”, the latter referring to cleaning procedures designed to lower the microbial content of equipment without necessarily achieving elimination of all microbial infectivity or viability.
e. Steam, gas or vapor sterilizable freezedrying equipment with a condenser capacity of 10 kg of ice or greater in 24 hours (10 liters of water or greater in 24 hours) and less than 1000 kg of ice in 24 hours (less than 1,000 liters of water in 24 hours).
f.1. Protective full or half suits, or hoods dependant upon a tethered external air supply and operating under positive pressure;
Technical Note: This entry does not control suits designed to be worn with self-contained breathing apparatus. f.2. Class III biological safety cabinets or isolators with similar performance standards, e.g., flexible isolators, dry boxes, anaerobic chambers, glove boxes or laminar flow hoods (closed with vertical flow).
g. Chambers designed for aerosol challenge testing with microorganisms, viruses, or toxins and having a capacity of 1 m3 or greater.
g.2. Biocontainment chambers, isolators, or biological safety cabinets having all of the following characteristics, for normal operation: g.2.a. Fully enclosed workspace where the operator is separated from the work by a physical barrier; g.2.b. Able to operate at negative pressure; g.2.c. Means to safely manipulate items in the workspace; and g.2.d. Supply and exhaust air to and from the workspace is high-efficiency particulate air (HEPA) filtered. Note 1 to 2B352.g.2: 2B352.g.2 controls class III biosafety cabinets, as specified in the WHO Laboratory Biosafety Manual (3rd edition, Geneva, 2004) or constructed in accordance with national standards, regulations or guidance. Note 2 to 2B352.g.2: 2B352.g.2 does not control isolators ‘‘specially designed’’ for barrier nursing or transportation of infected patients.
h. Spraying or fogging systems and components therefor, as follows:
h.1. Complete spraying or fogging systems, specially designed or modified for fitting to aircraft, “lighter than air vehicles,” or “UAVs,” capable of delivering, from a liquid suspension, an initial droplet “VMD” of less than 50 microns at a flow rate of greater than 2 liters per minute;
h.2. Spray booms or arrays of aerosol generating units, specially designed or modified for fitting to aircraft, “lighter than air vehicles,” or “UAVs,” capable of delivering, from a liquid suspension, an initial droplet “VMD” of less than 50 microns at a flow rate of greater than 2 liters per minute; designed for fitting to the systems specified in paragraphs h.1 and h.2 of this ECCN.
g. * * * h. Aerosol inhalation equipment designed for aerosol challenge testing with microorganisms, viruses or toxins, as follows: h.1. Whole-body exposure chambers having a capacity of 1 cubic meter or greater. h.2. Nose-only exposure apparatus utilizing directed aerosol flow and having a capacity for the exposure of 12 or more rodents, or two or more animals other than rodents, and closed animal restraint tubes designed for use with such apparatus
Technical Notes:
1. “Aerosol generating units” are devices specially designed or modified for fitting to aircraft and include nozzles, rotary drum
atomizers and similar devices.
2. This ECCN does not control spraying or fogging systems and components, as specified in 2B352.h., that are demonstrated not to be capable of delivering biological agents in the form of infectious aerosols.
3. Droplet size for spray equipment or nozzles specially designed for use on aircraft or “UAVs” should be measured using either of the following methods (pending the adoption of internationally accepted standards):
a. Doppler laser method,
b. Forward laser diffraction method.
7A101 Accelerometers, other than those controlled by 7A001
a. Linear accelerometers designed for use in inertial navigation systems or in guidance missiles” having all of the following characteristics, and “specially designed” “parts” and “components” therefor:
a.1. ‘Scale factor’ “repeatability” less (better) than 1250 ppm; and
a.2. ‘Bias’ “repeatability” less (better) than 1250 micro g.
Note: The measurement of ‘bias’ and ‘scale factor’ refers to one sigma standard deviation with respect to a fixed calibration over a period of one year. b. Accelerometers of any type, designed for use in inertial navigation systems or in guidance systems of all types, specified to function at acceleration levels greater than 100
g.
Note to paragraph (b): This paragraph (b)
does not include accelerometers that are
designed to measure vibration or shock.
7A002 Gyros or angular rate sensors
a. Specified to function at linear acceleration levels less than or equal to 100 g and having any of the following:
a.1. A rate range of less than 500 degrees per second and having any of the following:
a.1.a. A “bias” “stability” of less (better) than 0.5 degree per hour, when measured in a 1 g environment over a period of one month, and with respect to a fixed calibration value; or
a.1.b. An “angle random walk” of less (better) than or equal to 0.0035 degree per square root hour;
or
Note: 7A002.a.1.b does not control ‘spinning mass gyros’. Technical Note: ‘Spinning mass gyros’are gyros which use a continually rotating mass to sense angular motion. a.2. A rate range greater than or equal to 500 degrees per second and having any of the following:
a.2.a. A “bias” “stability” of less (better) than 40 degrees per hour, when measured in a 1 g environment over a period of three minutes, and with respect to a fixed calibration value; or
a.2.b. An “angle random walk” of less (better) than or equal to 0.2 degree per square root hour; or Note: 7A002.a.2.b does not apply to ‘spinning mass gyros’. b. Specified to function at linear acceleration levels exceeding 100 g.
7A102 Gyros, other than those controlled by 7A002
a. All types of gyros, usable in rockets, missiles, or unmanned aerial vehicles capable of achieving a “range” equal to or greater than 300 km, with a rated “drift rate” ‘stability’ of less than 0.5 degrees (1 sigma or rms) per hour in a 1 g environment.
b. Gyros of any type, designed for use in inertial navigation systems or in guidance systems of all types, specified to function at acceleration levels greater than 100 g.
Technical Note: In this entry, the term ‘stability’ is defined as a measure of the ability of a specific mechanism or performance
coefficient to remain invariant when continuously exposed to a fixed operating condition. (This definition does not refer to
dynamic or servo stability.) (IEEE STD 528-2001 paragraph 2.247)
7A003 Inertial systems and “specially designed” “components
a. Inertial Navigation Systems (INS) (gimbaled or strapdown) and inertial equipment, designed for “aircraft,” land vehicles, vessels (surface or underwater) or “spacecraft,” for navigation,
attitude, guidance or control and having any of the following, and “specially designed” “components” therefor:
a.1. Navigation error (free inertial) subsequent to normal alignment of 0.8 nautical mile per hour (nm/hr) “Circular Error Probable” (“CEP”) or less (better); or
a.2. Specified to function at linear acceleration levels exceeding 10 g;
b. Hybrid Inertial Navigation Systems embedded with Global Navigation Satellite System(s) (GNSS) or with “Data-Based
Referenced Navigation” (“DBRN”) System(s) for navigation, attitude, guidance or control, subsequent to normal alignment and having an INS navigation position accuracy, after loss of
GNSS or “DBRN” for a period of up to 4 minutes, of less (better) than 10 meters “Circular Error Probable” (“CEP”);
c. Inertial measurement equipment for heading or True North determination and having any of the following, and “specially
designed” “components” therefor:
c.1. Designed to have heading or True North determination accuracy equal to, or less (better) than 0.07 deg sec(Lat) (equivalent to 6 arc minutes (rms) at 45 degrees latitude); or
c.2. Designed to have a non-operating shock level of 900 g or greater at a duration of 1 msec, or greater;
d. Inertial measurement equipment including Inertial Measurement Units (IMU) and Inertial
Reference Systems (IRS), incorporating accelerometers or gyros controlled by 7A001 or 7A002.
Note 1: The parameters of 7A003.a and 7A003.b are applicable with any of the following environmental conditions:
a. Input random vibration with an overall magnitude of 7.7 g (rms) in the first 0.5 hour and a total test duration of 1.5 hour per
axis in each of the 3 perpendicular axes, when the random vibration meets all of the following:
1. A constant Power Spectral Density(PSD) value of 0.04 g2/Hz over a frequency interval of 15 to 1,000 Hz; and
2. The PSD attenuates with frequency from 0.04 g2/Hz to 0.01 g2/Hz over a frequency interval from 1,000 to 2,000 Hz;
b. An angular rate capability about one or more axes of equal to or more than +2.62 rad/s (150 deg/s); or
c. According to national standards equivalent to a. or b. of this note. Note 2: 7A003 does not control inertial navigation systems which are certified for use on “civil aircraft” by civil authorities of a Wassenaar Arrangement Participating State, see Supplement No. 1 to Part 743 for a list of these countries. Note 3: 7A003.c.1 does not control theodolite systems incorporating inertial equipment “specially designed” for civil
surveying purposes. Technical Note: 7A003.b refers to systems in which an INS and other independent navigation aids are built into a single unit
(embedded) in order to achieve improved performance.
7A103 Instrumentation, navigation equipment and systems, other than those
controlled by 7A003,
a. Inertial or other equipment using accelerometers or gyros controlled by 7A001, 7A002, 7A101 or 7A102 and systems
incorporating such equipment, and “specially designed” “parts” and “components” therefor;
Note 1: 7A103.a does not control equipment containing accelerometers “specially designed” and developed as MWD
(Measurement While Drilling) sensors for use in down-hole well services operations.
Note 2: 7A103.a does not control inertial or other equipment using accelerometers or gyros controlled by 7A001 or 7A002 that are only NS controlled.
b. Integrated flight instrument systems, which include gyrostabilizers or automatic pilots, designed or modified for use in rockets, missiles, or unmanned aerial vehicles capable
of achieving a “range” equal to or greater than 300 km, and “specially designed” “parts” and “components” therefor.
c. Integrated Navigation Systems, designed or modified for use in rockets, missiles, or unmanned aerial vehicles capable of achieving a “range” equal to or greater than 300 km and capable of providing a navigational accuracy of 200m Circular Error Probable (CEP) or less.
Technical Note: An ‘integrated navigation system’ typically incorporates the following “parts” and “components”:
1. An inertial measurement device (e.g., an attitude and heading reference system, inertial reference unit, or inertial navigation
system);
2. One or more external sensors used to update the position and/or velocity, either periodically or continuously throughout the flight (e.g., satellite navigation receiver, radar altimeter, and/or Doppler radar); and
3. Integration hardware and software.
7A004 ‘Star trackers’ and “components” therefor
a. ‘Star trackers’ with a specified azimuth accuracy of equal to or less (better) than 20 seconds of arc throughout the specified lifetime of the equipment;
b. “Components” “specially designed” for equipment specified in 7A004.a as follows:
b.1. Optical heads or baffles;
b.2. Data processing units.
Technical Note: ‘Star trackers’ are also referred to as stellar attitude sensors or gyroastro compasses.
