Dr. Robert Edwards. Biosketch
Dr. Robert A. Edwards, B. Sc. D. Phil.
Professor of Computer Science and Biology
Department of Computer Science
GMCS411
5500 Campanile Drive
San Diego, CA 92182-7720
Tel: 619 594 1672
Fax: 619 594 6746
Email: redwards@mail.sdsu.edu
Web Site:
http://edwards.sdsu.edu/research
Google Scholar:
http://scholar.google.com/citations?user=e7fvl1kAAAAJ
Curriculo Lattes:
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4327547Y9
Positions and affiliations
Professor, Department of Computer Science, San Diego State University
Professor, Department of Biology, San Diego State University
Education, Positions, And Employment Experience
Year
Position
2015-
Professor, Department of Computer Science, San Diego State University
2015-
Professor, Department of Biology, San Diego State University
2015
Visiting Scientist, University of Queensland Diamantina Institute
2011-2015
Associate Professor, Department of Computer Science, San Diego State University
2011-2015
Associate Professor, Department of Biology, San Diego State University
2010-2015
Visiting Scholar, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
2007-2011
Assistant Professor, Department of Computer Science, San Diego State University
2007-2011
Assistant Professor, Department of Biology, San Diego State University
2007-2015
Visiting Scientist, Argonne National Laboratory, Argonne, IL
2004-
Fellow, Fellowship for Interpretation of Genomes
2004-2007
Adjunct Assistant Professor, Department of Biology, San Diego State University
2005-2007
Adjunct Assistant Professor, Computational Sciences Research Center, San Diego State
University, San Diego, CA
2004-2008
Adjunct Assistant Professor, The Burnham Institute for Medical Research, San Diego,
CA
2003-2004
Assistant Facility Manager, University of Tennessee BSL3 Laboratory
2001-2004
Director Bioinformatics, University of Tennessee Medical Resource Center
2001-
Fellow, Center for Microbial Sciences, San Diego, CA
2000-2004
Assistant Professor of Microbiology. Department of Molecular Sciences, University of
Tennessee Health Sciences Center, Memphis, TN.
1999-2002
Consultant, Integrated Genomics, Inc, Chicago, IL
1997-2000
Postdoctoral Researcher at the University of Illinois. Genetic and pathogenic studies on
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Dr. Robert Edwards. Biosketch
Salmonella enterica serovar Enteritidis
1994-1997
Postdoctoral Researcher at the University of Pennsylvania, Philadelphia. Molecular
genetic studies on the 987P fimbriae of enterotoxigenic E. coli.
1991-1994
D. Phil. Microbial Genetics. University of Sussex, Brighton, England.
1987-1991
B. Sc. Science and the Environment, De Montfort University, Leicester, England
Extramural Grants:
2013
NSF CNS 1305112: Computational Metagenomics (PI). $560,934 direct costs.
2013
NSF DEB 1321737. US/Indonesia Workshop on Biodiversity (PI). $62,402 direct costs.
2013
NSF MCB 1330800. Connecting Genotype and Phenotype (PI). $900,000 direct costs.
2013
NSF – TUES Type II: STEMM: Sequencing Technology Education Using Microbial
Metagenomes (Co-PI) $600,000 direct costs.
2011
USGS – Development of an interface of Prosilica GigE Cameras. $40,000 direct costs.
2010
Dept. Education – FIPSE-CAPES San Diego-Brazil Consortium on Marine Sciences (PI)
$250,000 direct costs.
2010
NSF – TUES Type I: Microbes, Metagenomes and Marine Mammals: Enabling the Next
Generation of Scientists to Enter the Genomic Era (Co-PI) $200,000 direct costs.
2010
NSF DEB 1046413 – Dimensions: Shedding Light on Viral Dark Matter - Genetic,
Taxonomic, and Functional Diversity of Coral Reef Viromes (Co-PI) $2,999,783 direct costs.
2008
NSF DBI 0850356 – Collaborative Research: PHANTOME: PHage ANnotation TOols and
Methods (PI) $873,111 direct costs.
2004
NSF – GE:GenEn: Solar Saltern Extremophage: Genomics and Population Modeling (Co-PI)
$1,652,581 direct costs.
REU Supplements: (support undergraduate research in my lab):
2014
Supplement to NSF MCB 1330800
2013
Supplement to NSF DEB 1046413
2011
Supplement to NSF DBI 0850356
2010
Supplement to NSF DBI 0850356
National Awards:
2011
Kavli Frontiers Fellow, National Academy of Sciences
Institutional Awards:
2015
San Diego Chapter Sigma Xi Award for Distinguished Achievement
2015
SDSU Outstanding International Scholar
2012
SDSU Most Influential Faculty Member
2009
SDSU Most Influential Faculty Member
2008
SDSU Teacher/Scholar Award
2004
UTHSC Award for Outstanding Teacher in the Graduate Health Sciences Program
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Dr. Robert Edwards. Biosketch
Meeting and Workshop Organizer:
2015
Genomics, Metagenomics, and Viromics, Flinders University, Adelaide, Australia
2015
Genomics, Metagenomics, and Viromics, San Diego State University
2015
High performance computing workshop, San Diego State University
2013
Scientific Chair, LIPI-NSF, Workshop on Dimensions of Biodiversity, Cibinong, Indonesia
2/2013
2002
Microbes: Invisible Invader...Amazing Allies. Public Exhibition. Pink Palace Museum,
Memphis
2002
UT Bioinformatics Retreat
2000
Salmonella Genome Annotation Meeting, University of Illinois
1999
Advanced Bacterial Genetics Conference for Young Investigators. With Dr. Mike Laird,
Genentech
Invited Advisor:
2013
ASM Viruses
2012
Gordon and Betty Moore Foundation Marine Microbial Initiative Review
2009
USDA Panel on Metagneomics, Maryland
2007
US/EU Workshop on Marine Genomics. Washington, DC.
2005
US/EU Workshop on Marine Genomics. Bremen, Germany
2005
National Academy of Sciences Panel on Metagenomics, Washington, DC.
2004
NIH review and update of the BMBL Handbook. NIH, Bethesda, Maryland
2003
American Society of Microbiology, Washington, DC
Peer Reviewer (2000-present):
Journals/Books:
AAAS
Genomics
Nucleic Acids Research
AEM
Infection and Immunity
PeerJ
ASM Press
Int. J. of Mol. Sci.
PLoS Biology
Bioinformatics
ISME J
PLoS Genetics
BioTechniques
J. Bacteriology
PLOS Genetics
BMC Bioinformatics
Microbial Ecology
PLoS One
BMC Genomics
Mol. Biol. Evol.
PNAS
BMC Research Notes
Molecular Microbiology
Res. Microbiology
Drug Discovery
Nature
TIM
Env. Microbiology
Nature Methods
Trends in Microbiology
Genome Research
Nucl. Acids Rev.
Grant Reviews:
Am. Assoc. Advancement of Science
National Science Foundation
American Cancer Society
US Dept. of Agriculture
National Institutes of Health
Dept. of Energy
Member, Professional Societies:
American Society for Microbiology
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Dr. Robert Edwards. Biosketch
International Society for Computational Biology
International Committee on the Taxonomy of Viruses, Bacteria and Archaeal Viruses Subcommitee
Society for General Microbiology (UK)
American Association for the Advancement of Science
Sigma Xi
Association of Computing Machinery
Institute of Electrical and Electronic Engineers
Outreach:
2014
Interviewed on Science Friday (broadcast on NPR) about our identification of a novel virus
2013
Particpant in the Line Islands Expedition, Rediscovering the Coral Reefs.
2011
ASM Branch Enhancement Activity Workshop Presenter
2010
Public Lecture on the Line Islands, San Diego Council of Divers
2007
Particpant in the Line Islands Expedition, Rediscovering the Coral Reefs.
2005
Particpant in the Line Islands Expedition, Rediscovering the Coral Reefs
2003
Registered with the FBI and CDC to ship, receive, and handle Select Agents and other
pathogens
2003
Certified to work in BSL-3 laboratory conditions.
2000
Interviewed on NPR about Salmonella infections.
Peer-Reviewed Publications
Citation metrics
As of January 1
st
, 2016. Updated citation metrics can be found at
http://scholar.google.com/citations?
user=e7fvl1kAAAAJ
All
Last 5 years
Citations
18,358 13,260
h-index
52
47
i10-index
93
88
Journal Manuscripts:
1.
Knowles B, Silveira CB, Bailey BA, Barott K, Cantu A, Cobián-Güemes AG, Coutinho FH,
Dinsdale E, Felts B, Furby KA, George EE, Green KT, Gregoracci GB, Haas AF, Haggerty
JM, Hester ER, Hisakawa NG, Kelly LW, Lim YW, Little M, Luque A, McDole-Somera T,
McNair K, de Oliveira LS5, Quistad SD, Robinett NL, Sala E, Salamon P, Sanchez SE,
Sandin S, Silva GGZ, Smith J, Sullivan C, Thompson C, Vermeij MJA, Youle M, Young C,
Zgliczynski B, Brainard R, Edwards RA, Nulton J, Thompson F, Rohwer F. Lytic to
Temperate Switching of Viral Communities. Nature. March 16th 2016.
2.
Lopes FAC, Catão ECP, Santana RH, Cabral A de S, Paranhos R, Rangel TP, Rezende CE de,
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Dr. Robert Edwards. Biosketch
Edwards RA, Thompson CC, Thompson FL, Kruger RH. 2016. Microbial Community
Profile and Water Quality in a Protected Area of the Caatinga Biome. PLoS ONE
11:e0148296.
3.
Edwards RA, McNair K, Faust K, Raes J, Dutilh BE. 2016. Computational approaches to
predict bacteriophage–host relationships. FEMS Microbiology Reviews fuv048. Editors
choice for 2016. Top three most downloaded articles in FEMS Micro. Rev.
4.
Yue M, Han X, Masi LD, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP,
Zhao S, McDermott PF, Weill F-X, Mainil JG, Arze C, Fricke WF, Edwards RA, Brisson
D, Zhang NR, Rankin SC, Schifferli DM. 2015. Allelic variation contributes to bacterial
host specificity. Nat Commun 6:8754.
5.
Kryshtafovych A, Moult J, Baslé A, Burgin A, Craig TK, Edwards RA, Fass D, Hartmann MD,
Korycinski M, Lewis RJ, Lorimer D, Lupas AN, Newman J, Peat TS, Piepenbrink KH,
Prahlad J, van Raaij MJ, Rohwer F, Segall AM, Seguritan V, Sundberg EJ, Singh AK,
Wilson MA, Schwede T. 2015. Some of the most interesting CASP11 targets through the
eyes of their authors. Proteins.
6.
Silva GGZ, Green KT, Dutilh BE, Edwards RA. 2015. SUPER-FOCUS: A tool for agile
functional analysis of shotgun metagenomic data. Bioinformatics btv584.
7.
McNair K, Edwards RA. 2015. GenomePeek—an online tool for prokaryotic genome and
metagenome analysis. PeerJ 3:e1025. Chosen as one of the top 10 genomics papers in PeerJ
2013-2015.
8.
Meirelles PM, Amado-Filho GM, Pereira-Filho GH, Pinheiro HT, de Moura RL, Joyeux J-C,
Mazzei EF, Bastos AC, Edwards RA, Dinsdale E, Paranhos R, Santos EO, Iida T, Gotoh K,
Nakamura S, Sawabe T, Rezende CE, Gadelha LMR Jr, Francini-Filho RB, Thompson C,
Thompson FL. 2015. Baseline Assessment of Mesophotic Reefs of the Vitória-Trindade
Seamount Chain Based on Water Quality, Microbial Diversity, Benthic Cover and Fish
Biomass Data. PLoS ONE 10:e0130084.
9.
Navarrete AA, Diniz TR, Braga LPP, Silva GGZ, Franchini JC, Rossetto R, Edwards RA, Tsai
SM. 2015. Multi-Analytical Approach Reveals Potential Microbial Indicators in Soil for
Sugarcane Model Systems. PLoS ONE 10:e0129765.
10.
Sanchez SE, Cuevas DA, Rostron JE, Liang TY, Pivaroff CG, Haynes MR, Nulton J, Felts B,
Bailey BA, Salamon P, Edwards RA, Burgin AB, Segall AM, Rohwer F. 2015. Phage
Phenomics: Physiological Approaches to Characterize Novel Viral Proteins. Journal of
Visualized Experiments.
11.
Matthews TD, Schmieder R, Silva GGZ, Busch J, Cassman N, Dutilh BE, Green D, Matlock B,
Heffernan B, Olsen GJ, Farris Hanna L, Schifferli DM, Maloy S, Dinsdale EA, Edwards
RA. 2015. Genomic Comparison of the Closely-Related Salmonella enterica Serovars
Enteritidis, Dublin and Gallinarum. PLoS ONE 10:e0126883.
12.
Adriaenssens EM, Edwards R, Nash JHE, Mahadevan P, Seto D, Ackermann H-W, Lavigne R,
Kropinski AM. 2015. Integration of genomic and proteomic analyses in the classification of
the Siphoviridae family. Virology 477:144–154.
13.
Aziz, R.K., Dwivedi, B., Akhter, S., Breitbart, M., and R.A. Edwards 2015. Multidimensional
metrics for estimating phage abundance, distribution, gene density, and sequence coverage
in metagenomes . Front. Microbiol. doi: 10.3389/fmicb.2015.00381.
14.
Brettin, T., J.J. Davis, T. Disz, R.A. Edwards, S. Gerdes, G.J. Olsen, R. Olson, R., Overbeek,
B. Parrello, G.D. Pusch, S. Maulik, J.A. Thomason, R. Stevens, V. Vonstein, A.R. Wattam,
Page 5 of 30
Dr. Robert Edwards. Biosketch
and F. Xia 2015. RASTtk: A modular and extensible implementation of the RAST algorithm
for building custom annotation pipelines and annotating batches of genomes. Nature Sci.
Rep. 5. doi: 10.1038/srep08365
15.
Thompson, C.C., Amaral, G.R., Campeão, M., Edwards, R.A., Polz, M.F., Dutilh, B.E., Ussery,
D.W., Sawabe, T., Swings, J., and Thompson, F.L. 2015. Microbial taxonomy in the post-
genomic era: Rebuilding from scratch? Arch Microbiol 1–12.
16.
G.G.Z. Silva
g
, B E. Dutilh, R A. Edwards. 2014. FORMAL: A model to identify organisms
present in metagenomes using Monte Carlo Simulation. biorxiv. doi:
http://dx.doi.org/10.1101/010801
17.
Dutilh BE, Cassman N
g
, McNair K, Sanchez S
g
, Silva GGZ
g
, Boling L
u
, Barr JJ
p
, Speth DR,
Seguritan V
g
, Aziz RK, Felts B, Dinsdale EA, Mokili JL, Edwards RA. 2014. A highly
abundant bacteriophage discovered in the unknown sequences of human faecal
metagenomes. Nature Communications 5:4498.
http://dx.doi.org/10.1038/ncomms5498
2014 journal impact factor 10.742. Cited by 1
18.
Cuevas, D.
g
, Garza, D., Sanchez, S.
g
, Rostron, J., Henry, C., Vonstein, V., Overbeek, R., Segall,
A., Rohwer, F., Dinsdale, EA., Edwards RA. 2014. Elucidating genomic gaps using
phenotypic profiles. F1000Research.
http://dx.doi.org/10.12688/f1000research.5140.1
(No
impact factor yet.)
19.
Lim YW
g
, Haas A
p
, Cuevas D
g
, Silva GGZ
g
, Dinsdale E, Lee C, Harkins TT, Rohwer F,
Edwards RA. Sequencing At Sea: Challenges and Experiences in Ion Torrent Sequencing
during the 2013 Southern Line Islands Research Expedition. PeerJ 2:e520
http://dx.doi.org/10.7717/peerj.520
(No impact factor yet.) This article was picked as one
of the PeerJ Top 20 articles for 2014.
20.
Dutilh BE, Tompson C, Vicente AC, Marin MA, Lee CF, Silva GGZ
g
, Schmieder R, Andrade
BGN, Chimetto L, Cuevas D, Garza DR, Okeke IN, Aboderin O, Spangler J, Ross T,
Dinsdale EA, Thompson FL, Harkins TT, Edwards RA. 2014 Comparative genomics of
274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions.
BMC Genomics 15:654
http://dx.doi.org/10.1186/1471-2164-15-654
2014 journal impact
factor 4.041
21.
Kelly LW
g
, Williams GJ
p
, Barott KL
p
, Carlson CA, Dinsdale EA, Edwards RA, Haas AF
p
,
Haynes M, Lim YW
g
, McDole T
g
, Nelson CE
g
, Sala E, Sandin SA, Smith JE, Vermeij MJA,
Youle M, Rohwer F. 2014. Local genomic adaptation of coral reef-associated microbiomes
to gradients of natural variability and anthropogenic stressors. Proc. Natl. Acad. Sci.
111:10227-10232
http://dx.doi.org/10.1073/pnas.1403319111
2014 journal impact factor
9.809. Cited by 1
22.
Silva GGZ
g
, Cuevas DA
g
, Dutilh BE, Edwards RA. 2014. FOCUS: an alignment-free model
to identify organisms in metagenomes using non-negative least squares. PeerJ 2:e425. (No
impact factor yet.).
http://dx.doi.org/10.7717/peerj.425
Cited by 1
23.
Overbeek R, Olson R, Pusch GD, Olsen GJ, Davis JJ, Disz T, Edwards RA, Gerdes S, Parrello
B, Shukla M, Vonstein V, Wattam AR, Xia F, Stevens R. 2014. The SEED and the Rapid
Annotation of microbial genomes using Subsystems Technology (RAST). Nucleic Acids
Res. 42:D206-14.
http://dx.doi.org/10.1093/nar/gkt1226
2014 journal impact factor 8.808.
Cited by 28
24.
Lim, Y.W., Schmieder, R., Haynes, M., Furlan, M., Matthews, T.D., Whiteson, K., Poole, S.J.,
Hayes, C.S., Low, D.A., Maughan, H., Edwards, R.A., Conrad, D., and F. Rohwer. 2013.
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Dr. Robert Edwards. Biosketch
Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung,
based on a genome reconstructed from metagenomic data. PLoS One 8:e64285.
http://dx.doi.org/10.1371/journal.pone.0064285
2014 journal impact factor 3.534. Cited by
6
25.
Lim, YW.
g
, Evangelista, J., Schmieder, R.
g
, Bailey, B., Haynes, M., Furlan, M., Maughan, H.,
Edwards, R., Rohwer, F., and D. Conrad. 2014. Clinical Insights from Metagenomic
Analysis of Cystic Fibrosis Sputum. J. Clin. Microbiol. 52:425-437.
http://dx.doi.org/10.1128/JCM.02204-13
2014 journal impact factor 4.232. Cited by 5
26.
Edwards RA, Haggerty JM
g
, Cassman N
g
, Busch JC
g
, Aguinaldo K
g
, Chinta S
g
, Vaughn MH,
Morey R, Harkins TT, Teiling C, Fredrikson K, Dinsdale EA. 2013. Microbes,
metagenomes and marine mammals: enabling the next generation of scientist to enter the
genomic era. BMC Genomics 14:600.
http://dx.doi.org/10.1186/1471-2164-14-600
2014
journal impact factor 4.041. Cited by 1
27.
Silva, G.G.
g
, Dutilh, B.E., Matthews, T.D.
p
, Elkins, K.
u
, Schmieder, R., Dinsdale E.A., and R.A.
Edwards. 2013. Combining de novo and reference-guided assembly with scaffold_builder.
Source Code for Biology and Medicine 2013, 8:23.
http://dx.doi.org/10.1186/1751-0473-8-
23
(No impact factor yet). Cited by 2
28.
Thompson, CC., Chimetto, L.
g
, Edwards, RA., Swings, J., Stackebrandt E., and FL Thompson.
2013. Microbial genomic taxonomy. BMC Genomics 2013, 14:913
http://dx.doi.org/10.1186/1471-2164-14-913
2014 journal impact factor 4.041. Cited by 6
29.
Thompson, C.C., Silva, G.G.Z., Vieira, N.M., Edwards, R., Vicente, A.C.P., and Thompson,
F.L. Genomic Taxonomy of the Genus Prochlorococcus. Microbial Ecology 1–11.
http://dx.doi.org/10.1007/s00248-013-0270-8
2014 journal impact factor 3.118. Cited by 6
30.
Dinsdale EA, Edwards RA, Bailey B, Tuba I, Akhter S
g
, McNair K, Schmieder R
g
, Apkarian
N
u
, Creek M
u
, Guan E
u
, Hernandez M
u
, Isaacs K
u
, Peterson C
u
, Regh T
u
, Ponomarenko V.
2013. Multivariate analysis of functional metagenomes. Front. Genet. 4::41.
http://dx.doi.org/10.3389/fgene.2013.0004
1
(No impact factor yet). Cited by 8
31.
Dutilh, B.E., Backus, L., Edwards, R.A., Wels, M., Bayjanov, J.R., and S.A.F.T. van Hijum
2013. Explaining microbial phenotypes on a genomic scale: GWAS for microbes. Brief
Funct Genomics. 2013 Jul;12(4):366-80.
http://dx.doi.org/10.1093/bfgp/elt008
2014 journal
impact factor 3.427. Cited by 2
32.
Dwivedi, B., Xue, B., Lundin, D., Edwards R.A., and Breitbart, M. 2013. A bioinformatic
analysis of ribonucleotide reductase genes in phage genomes and metagenomes. BMC
Evolutionary Biology.
http://dx.doi.org/10.1186/1471-2148-13-33
2014 journal impact
factor 3.407. Cited by 13
33.
Garcia GD, Gregoracci GB, de O Santos E, Meirelles PM, Silva GG, Edwards R.A., Sawabe T,
Gotoh K, Nakamura S, Iida T, de Moura RL, Thompson FL. 2013. Metagenomic Analysis
of Healthy and White Plague-Affected Mussismilia braziliensis Corals. Microb Ecol.
65:1076-1086
http://dx.doi.org/10.1007/s00248-012-0161-4
2014 journal impact factor
3.118. Cited by 13
34.
Frank JA, Lorimer D, Youle M, Witte P, Craig T, Abendroth J, Rohwer F, Edwards R.A., Segall
AM, Burgin AB Jr. 2013. Structure and function of a cyanophage-encoded peptide
deformylase. ISME J.
http://dx.doi.org/10.1038/ismej.2013.4
2014 journal impact factor
9.267. Cited by 3
35.
Akhter S
g
, Bailey BA, Salamon P, Aziz RK, Edwards RA. 2013. Applying Shannon’s
Page 7 of 30
Dr. Robert Edwards. Biosketch
information theory to bacterial and phage genomes and metagenomes. Nature Scientific
Reports. 3:1033
http://dx.doi.org/10.1038/srep01033
2014 journal impact factor 5.078.
Cited by 4
36.
Lim YW
g
, Schmieder R
g
, Haynes M, Willner D, Furlan M
g
, Youle M, Abbott K, Edwards R,
Evangelista J, Conrad D, Rohwer F. 2012. Metagenomics and metatranscriptomics:
Windows on CF-associated viral and microbial communities. Journal of Cystic Fibrosis.
http://dx.doi.org/10.1016/j.jcf.2012.07.009
2014 journal impact factor 3.82. Cited by 19
37.
Dutilh, B. E., Schmieder, R.
g
, Nulton, J., Felts, B., Salamon, P., Edwards R. A. and J. L.
Mokili. 2012. Reference-independent comparative metagenomics using cross-assembly:
crAss. Bioinformatics.
http://dx.doi.org/10.1093/bioinformatics/bts613
2014 journal impact
factor 4.621. Cited by 9.
38.
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