Outpatient antibiotic options
-Cipro (ciprofloxacin) and Augmentin (amoxicillin/clauvanate)- most recommended by the IDSA
-Other options (not as well studied)
-Ciprofloxacin monotherapy
-Ciprofloxacin plus clindamycin
-Levaquin (levofloxacin) monotherapy
Inpatient IV antibiotic options
-Broad spectrum coverage
-Cefepime 2 grams IV or
-Meropenem 2 grams IV or
-Zosyn (piperacillin/tazobactam) 3.375 grams IV
Gram positive coverage- not recommended by IDSA for routine use
-Consider in patients who are hemodynamically ill, have a port infection, pneumonia, a skin or soft tissue infection
-Dosing- 15 to 20 mg/kg IV- alternative 25 to 30 mg/kg first dose for critically ill patients to achieve rapid therapeutic levels
PEARL: Make sure to dose your vancomycin by weight. Unless your patient weight 50 kilograms then the “standard 1 gram of vanc” will be an underdose. Max single dose is 2 grams
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