General microbiology


A. Serological and gene diagnostics



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A. Serological and gene diagnostics
B. Virus isolation in cell culture and its identification by CPE
C. Detection of virions in blood by electron microscopy
D. Isolation of the virus in laboratory animals (Nt)
E. Isolation of the virus in chicken embryos
5. The donor who for a long time didn't donate the blood was investigated with IFA method. Anti-HBs antibodies were revealed. What does positive result of IFA in this case mean?
A. Chronic hepatitis В B. Acute hepatitis B
C. Acute hepatitis C D. Chronic hepatitis С E. Previous hepatitis B
6. Examination of a 27-year-old donor who had not donated blood for a long time revealed HBs antibodies detected by ELISA method. In this case, the positive ELISA results indicate that the donor:
A. Had hepatitis B
B. Has acute hepatitis B C. Has acute hepatitis C
D. Has chronic hepatitis B E. Has chronic hepatitis C
7. Immune-enzyme reaction revealed in blood serum HBs-antigen. What disease is this antigene associated with?
A. Viral hepatitis type B B. Viral hepatitis A
C. AIDS D. Tuberculosis E. Syphilis
8. Immune-enzyme assay has detected HBs antigen in blood serum. What disease is it characteristic of?
A. Viral hepatitis type B
B. Viral hepatitis type A
C. AIDS
D. Tuberculosis
E. Syphilis
9. During surgical operation a blood transfusion was made. The blood must be checked to find antigens of some disease. What disease is expected to be found?
A. Viral hepatitis B B. Viral hepatitis A
C. Adenovirus D. Enterovirus E. Viral hepatitis E
10. Hepatitis B is diagnosed through laboratory tests that determine the presence of HBA-DNA in blood serum of the patient. What reference method is applied for this purpose?
A. Polymerase chain reaction B. Hybridization method
C. Hybridization signal amplification method
D. Ligase chain reaction method E. ELISA diagnostic method
11. A patient has been hospitalized with provisional diagnosis of virus B hepatitis. Serological reaction based on complementation of antigen with antibody chemically bound to peroxidase or alkaline phosphatase has been used for disease diagnostics. What is the name of the applied serological reaction?

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