General microbiology

. Gel precipitation reaction
B. Agglutination reaction on a glass slide
C. Complement binding reaction
D. Hemolysis reaction E. Ring precipitation reaction
24. A 7 year old girl was taken to an infectious diseases hospital. She had complaints of high temperature, sore throat, general weakness. A doctor assumed diphtheria. What will be crucial proof of diagnosis after defining pure culture of pathogenic organism?
A. Toxigenity test B. Detection of volutine granules
C. Hemolytic ability of pathogenic orhanism
D. Cystinase test E. Phagolysability
25. A 7 y.o. girl was admitted to the infectious diseases hospital with fever, sore throat, common weakness. A doctor suspected diphtheria. What would be crucial for diagnosis confirmation after pure culture of causative agent had been singled out?
A. Toxigenity test B. Detection of volutine granules
C. Hemolytic ability of a causative agent
D. Cystinase test E. Phagolysability
26. A patient has pure culture of diphtheria corynebacteria. What immunological reaction should be used in order to determine bacteria toxigenity?
A. Precipitation in agar B. Agglutination
C. Complement binding D. Inhibition of hemagglutination
E. Indirect hemagglutination
27. In order to establish the level of antidiphtheritic immunity in a child it was decided to use a passive hemagglutination test. This task can be completed by the sensibilization of erythrocytes by:
A. Diphtheria anatoxin B. Diphtheria antitoxin
C. Diphtheria bacillus antigens
D. Antidiphtheric serum E. -
28. A patient with suspected diphtheria went through bacterioscopic examination. Examination of throat swab revealed rod-shaped bacteria with volutin granules. What etiotropic preparation should be chosen in this case?
A. Antidiphtheric antitoxic serum B. Bacteriophage
C. Diphtheria antitoxin D. Eubiotic E. Interferon
29. Bacterioscopic examination of a smear from the pharynx of a diphtheria suspect revealed bacilli with volutine granules. What etiotropic drug should be chosen in this case?
A. Antidiphtheritic antitoxic serum B. Bacteriophage
C. Interferon D. Eubiotic E. Diphtheritic anatoxin
30. A child with diphtheria 10 days after injection of antitoxic antidiphtherial serum has developed skin rash, accompanied by severe itch, rising temperature up to 38⁰C and joints pain. What is the cause of these symptoms?
A. Delayed type of hypersensitivity B. Anaphylacsis
C. Contact allergy D. Atopia E. Serum sickness
31. A 16-year-old adolescent was vaccinated with DTP. In eight days there was stiffness and pain in the joints, subfebrile temperature, urticarial skin eruption, enlargement of inguinal, cervical lymph nodes and spleen. What kind of allergic reaction is observed?
A. Immunocomplex B. Hypersensitivity of immediate type
C. Cytoxic D. Hypersensitivity of delayed type E. –
32. It is necessary to carry out preventive vaccination of a student group because of an occurrence of diphtheria. Which preparation should be used for the creation of the artificial active immunity?
A. Diphtheria anatoxin B. Specific immunoglobulin
C. DTP vaccine D. Inactivated bacteria vaccine
E. Anti-diphtheria serum
33. Vaccination is done by means of a toxin that has been neutralized by a formaldehyde (0,4%) at a temperature 37 – 40⁰C for four weeks. Ramond was the first to apply this preparation for diphtheria prophylaxis. What preparation is it?
A. Anatoxin B. Immunoglobulin C. Antitoxic serum
D. Adjuvant E. Inactivated vaccine
34. Diphtheria exotoxin had been treated with 0,3-0,4% formalin and kept in a thermostat for 30 days at a temperature of 40^oC.What preparation was obtained as a result of these manipulations?
A. Anatoxin B. Antitoxin C. Diagnosticum
D. Therapeutic serum E. Diagnostic serum
35. In an inhabited locality there is an increase of diphtheria during the last 3 years with separate outbursts in families. What measure can effectively influence the epidemic process of diphtheria and reduce the morbidity rate to single cases?
A. Immunization of the population
B. Hospitalization of patients C. Detection of carriers
D. Early diagnostics E. Disinfection in disease focus
36. An 11-year-old girl has been immunized according to her age and in compliance with the calendar dates. What vaccinations should the children receive at this age?
A. Diphtheria and tetanus B. TB
C. Polio D. Hepatitis B E. Pertussis
36. In a closed community it is necessary to determine community members immunity to diphtheria and verify the need for their vaccination. What investigation is necessary in this case?
A. Check medical records for vaccination.
B. Test community members for diphtheria bacillus carriage.