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TEST 10 - Dyslexia
People who left school unable to read were often dismissed as being lazy. Some probably were but
many were simply unable to learn because they were dyslexic. Four key findings now suggest that dyslexia
is an organic problem and not a motivational one. Firstly, the brain anatomy of dyslexics differs slightly
from those of non-dyslexics. Secondly their brain functions as measured by electrical activity are dissimilar.
Thirdly they have behavioral differences apart from an inability to read. Finally, there is more and more
evidence to suggest that their condition is linked to particular genes.
The anatomical differences between the brains of dyslexics and non- dyslexics were first noticed in
1979 by Albert Galaburda of Harvard Medical School. He found two sorts of microscopic flaws in the
language centres of dyslexic’s brains. These are called ectoplasts and microgyria.
The language centres form part of the cerebral cortex and are situated on the left side of the brain. The
cortex consists of six layers of cells. An ectopia is a collection of nerve cells that push up from the lower
layers of the cortex into the outer ones, where they are not normally found. A microgyrus
is a small fold in
the cortex which results in a reduction in the normal number of layers from six to four.
The formation of microgyria causes confusion in the neutral connections between the language
centres and other parts of the brain. Microgyria have been induced in rat embryos and as adults these rats are
found to have a reduced ability in distinguishing between two sounds played in quick succession. This
inability to distinguish between two sounds in quick succession is also a symptom of dyslexia in people.
Dyslexia not only affects language centres but also causes brain abnormalities in visual pathways as
well. One such abnormality is the reduction in the cell size in the layers of the lateral geniculate nucleus.
This is where the nerve tracts which transmit information from the eyes to the visual cortex at the back of
the brain are found. This is significant as dyslexia is essentially an inability to deal with linguistic
information in visual form.
This parallel failure of visual and auditory systems is seen elsewhere in the brain. Guinevere Eden
and Thomas Zeffiro, who work at Georgetown University in Washington D. C. have found an example of it
using a brain scanning technique called functional magnetic resonance imaging.(MRI)
A fundamental characteristic of dyslexia is difficulty in processing written phenomes. Phenomes are
the units of sound which make up a language. By giving dyslexic people tasks
such as removing phenomes
from the beginning of words, while at the same time monitoring brain activity with their scanner, Dr Eden
and Dr Zeffiro were able to stimulate both the visual and auditory pathways simultaneously. Their findings
demonstrated that dyslexics showed low activity in a part of the brain called Brodmann’s area 37, another
part of the brain where visual and auditory information are handled in close proximity.
Dr Eden and Dr Zeffiro have also compared the brain activity of dyslexic and non-dyslexic readers
who were given a task not related to reading. Another symptom of dyslexia is difficulty in detecting visual
motion. On this basis Dr Eden and Dr Zeffiro devised a task whereby people were
asked to look at dots on a
screen and identify which of them was moving and in which direction. While monitoring brain activity with
the scanner, it was found that dyslexics performing this task showed significantly less brain activity in
Brodmann’s area 37 than non dyslexics. As this task did not require reading skills it could be used to test
children for incipient dyslexia before they reach the reading age; then they could be given special tuition.
To broaden their investigation, Dr Eden and Dr Zeffiro teamed up with Frank Wood and his
colleagues at the Wake Forest University School of Medicine in North Carolina,
an institution specializing
in dyslexia. Dr Eden and Dr Zeffiro borrowed some of its patients and monitored them in the fMRI machine
at Georgetown University. This was done both before and after the individuals had participated in an
intensive programme designed to improve their reading. Non- dyslexics were also scanned and used as
controls in the investigation.
The results were significant. After the programme, the participants showed enhanced brain activity
while reading. However this activity was not on the left side of the brain but in areas on the right side,