Miyastenia gravis prof. Dr. Aytekin Akyüz

IVIG

Timektomi

• displazi varsa jeneralize MG’de, timoma varsa tüm miyasteniklerde

Miyopatiler

• Largest group of neuromuscular diseases

• Most diverse group

• All show a loss of muscle fibers

• Proximal more than distal

• No involvement of the anterior horn cell, nerve axon, or neuromuscular junction

Miyopatiler

• Includes 6 subcategories

• 1. Endocrine Disorders

• 2. Metabolic Disorders

• 3. Myotonias

• 4. Periodic Paralysis

• 5. Polymyositis

• 6. Muscular Dystrophy

Endocrine Disorders

• • Myopathies caused by some malfunction of the endocrine system

• • Chronic

• • Examples: – Addison’s Disease – Cushing’s Syndrome – Thyrotoxic Myopathy

• • Respond to drug therapy – Consists primarily of replacing the deficient hormones

Metabolic Disorders

• Myopathies characterized by a deficiency of a specific enzyme resulting in muscle weakness

• Examples:

• McArdle’s Disease: Deficiency of the muscle enzyme myophosphorylase
• Pompe’s Disease: deficiency in Acid Maltase