Organizing co mmittee

partially exported abroad. (Registration certificate RUz - DV/M 03313/06/20, 
Registration certificate RF - No. FS-000247). As we all know, special attention is 
currently being paid to the production of medicines based on international GMP 
requirements, and to the creation of analytical methods based on the requirements of the 
USP international standard in terms of quality and quantity. 
Taking into account the above, we have conducted scientific research to increase the 
export potential of galantamine hydrobromide medicinal substance and to create a 
production technology of galantamine hydrobromide substance produced from the raw 
materials of 
Ungernia Victoris
that meets the requirements of international standards in 
terms of quality and quantity. As a result of our research, in the production of a high-
purity substance, alkaloids are extracted from plant raw materials using weak solutions 
of mineral acids, alkaloids are purified from the extract using the ion exchange method, 
the main substance is eluted from cations using an ethyl alcohol solution containing 
alkali, and galantamine alkaloid is extracted from the eluate, and its hydrobromide salt 
is extracted, the amount of additives in the substance has achieved the reduction 2 times 
with the help of recrystallization. At present, research is being conducted to study the 
chemical composition and harmlessness of small amounts of additional substances in 
the substance. As a result of the ongoing research, the possibility of producing a 
substance that meets the requirements of international standards will be created and the 
export potential of the product will be increased.
References 
1. Patent RUz №IAP 03421. Sposob polucheniya galantamine hydrobromide / 
Sadikov A.Z., Sagdullaev Sh.Sh., Azimova Sh.S., Abduazimov X.A. // Official 
newsletter. – 2007. – No. 4. 
2. Mullabaeva Z.U., Sadikov A.Z., Sagdullaev Sh.Sh. Development of a new method 
for quantification of galantamine hydrobromide in drug substance by HPLC // 7th 
International Symposium of the Chemistry of Natural Compounds. - Tashkent, 2007.- 
p.161.