Organizing co mmittee

 
phlojosibiriside 
IV 
ferulopsin A 
levistiside B 
References 
1.
Olennikov D.N., Kashchenko N.I., Chirikova N.K., 
et al.,
Molecules
, 
24
, 
2286 (2019). 
2.
Olennikov D.N., Chirikova N.K., 
Chem. Nat. Compd
., 
56
, 628 (2020) 
3.
Olennikov D.N., 
Metabolites
, 
13
, 3 (2023) 
The study was funded by a grant of the Ministry of Education and Science of Russia 
№ 121030100227-7, FSRG-2023-0027. 
O
O
O
H
O
H
O
O
O
O
O
O
H
O
H
OH
O
OH
OH
HO
OH
O
O
O
O
O
O
O
O
O
HO
HO
OH
O
O
O
O
O
OH

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Poster presentation 
50 
NEW ACYLATED C,O-GLYCOSYLFLAVONES AND ETHYL 
PHENOL GLUCOSIDES FROM CUCUMIS SATIVUS
Nina I. Kashchenko, Daniil N. Olennikov, Kristina V. Markova
Institute of General and Experimental Biology, Siberian Division, Russian Academy 
of Science, 6 Sakhyanovoy Street, 670047 Ulan-Ude, Russia 
 
Cucumber (
Cucumis sativus
L.) is a mass culture of greenhouse crop rotation; the 
amount of waste received from it is up to one million tons per year. Metabolites of 
vegetative green of 
C. sativus
are poorly studied and may be of practical importance as 
a source of biologically active agents for the treatment and prevention of socially 
significant diseases. Previous studies demonstrated the accumulation of the specific 
complex 
C
-glycosyl flavonoid phytoalexins cucumerins in leaves of cucumber infected 
by powdery mildew 
Podosphaera xanthii
[1], lately found in tissues of healthy plants 
[2]. Continuing our findings of cucumber bioactive metabolites, we used flash, column 
and preparative chromatography on NP- and RP-SiO
2
, polyamide, Sephadex LH-20 for 
the bioactivity-guided separation of phenolic components with pancreatic lipase 
inhibitory activity. Methanolic extract of 
C. sativus
non-infected leaves firstly yielded 
known acylated isovitexin derivatives isovitexin 2′′-
O
-(6′′′-
p
-coumaroyl/feruloyl)-
glucosides and isovitexin 4′-
O
-glucoside-2′′-
O
-(6′′′-
p
-coumaroyl/feruloyl)-glucosides 
[3] as well as new compounds