Poster presentation
135
FLAVONOIDS OF Oxytropis rosea
Sh.A. Sulaymonov
1
, B.D. Komilov
2
, K.A. Eshbakova
2
, G.O. Mamajanov
1
,
Sh.V. Abdullayev
1
1) Namangan State University, Namangan, Uychi st., 316, 160119
2) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent
e-mail: e_komila@yahoo.com
There are 606 species of
Oxytropis rosea
in the world flora. Of which there are 28
species in Uzbekistan and about 15 species in the Fergana Valley. It blooms in May and
june, bears fruit in june and july. About more than 127 substances have been isolated
from
Oxytropis
species given in the literature. Some species of this plant have been used
in medicine since ancient times to treat colds, skin tumors and tumors, as well as
various types of bleeding. In addition, it has been shown to be effective against
inflammation, neuroendocrine effects, and immune disorders.
Crushed and air-dry raw material (2000 g) was extracted exhaustively with 70%
alcohol at a room temperature. The combined extracts were distilled in vacuo, the
thickened residue was diluted with water (1:1) and shaken successively with extraction
gasoline, chloroform, ethyl acetate, and
n
-butanol.
The ethyl acetate extract was chromatographed on a silica gel column in a
chloroform-methanol (25:1-6:1) gradient system. As a result of chromatographic
separation, four compounds apigenin (
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